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Posthappy is an emergency contraceptive that can prevent pregnancy if taken within 72 hours of unprotected intercourse. So what is Posthappy and how is it used?
1. What is Posthappy?
Posthappy contains the active ingredient Levonorgestrel 0.75mg and excipients such as Povidon, Lactose, Magnesium stearate just enough for 1 tablet. The drug is prepared for human consumption in the form of tablets. Posthappy is packaged in a box, each box includes 1 blister x 2 tablets.
2. Uses of the drug Posthappy
2.1. Indications Posthappy is indicated in the following cases:
Not using contraception during intercourse; Using contraceptive methods such as: condoms, diaphragms, IUDs, interrupted intercourse but not effective. 2.2. Contraindications Posthappy is contraindicated in the following cases:
Users are hypersensitive to Levonorgestrel or any of its ingredients. Women who are pregnant, or suspected of being pregnant, have unusual vaginal bleeding without a diagnosis. Thrombophlebitis or active thromboembolic disease, acute hepatitis, benign or malignant neoplasm, history of breast, ovarian and uterine cancer. In a previous pregnancy with persistent itching, jaundice. 2.3. Pharmacodynamics Levonorgestrel is a synthetic derivative of Nortestosterone. This is an ovulatory inhibitor. The drug converts the proliferative phase of estrogen to the secretory phase with the endometrium. Levonorgestrel works to prevent pregnancy by preventing the implantation of an egg due to changes in the structure of the endometrium, creating a barrier to prevent sperm movement into the uterus when changing fluid. cervical mucus.
2.4. Pharmacokinetics After oral administration, Levonorgestrel is rapidly and almost completely absorbed. In serum, Levonorgestrel binds to globulin, which binds sex hormones to Albumin. The serum concentration that can inhibit ovulation is 0.2 mcg/l. After oral administration, peak serum concentrations occur after 1.1 ± 0.4 hours, after which the concentration of Levonorgestrel decreases gradually through elimination. Levonorgestrel and its metabolites are eliminated in faeces and urine in comparable proportions. The rate of drug elimination varies between individuals and averages 36 ± 13 hours. The gut microbiota may alter the enterohepatic circulation of oral contraceptives. In plasma, sulfate and glucuronic acid can conjugate with Levonorgestrel. These conjugates are excreted in the bile and then in the intestine, where they can be hydrolyzed by enteric bacteria and release the drug intact. Antibiotics inhibit this effect of bacteria, reducing the concentration of hormones in the blood plasma.
3. Dosage and how to use Posthappy
3.1. How to use Posthappy is taken orally, 2 tablets 1 time. Users take the first pill between 48 hours and 72 hours after intercourse, taking it as soon as possible. The second pill should be taken 12 hours after the first, no later than 16 hours. Within 2 hours after taking the first or second tablet, if vomiting occurs, take another pill immediately. After taking emergency contraceptive pills, it is important to use a barrier method of contraception such as condoms until the next menstrual period. Note: The drug can be taken at any time during the menstrual cycle, except for delayed menstruation. Do not take Posthappy for daily contraception and do not take more than 4 pills in 1 month.
3.2. Overdose and treatment There have been no studies to show that an overdose of oral contraceptives causes serious adverse effects. If an overdose is detected early within 1 hour and with a large dose, it should be treated with gastric lavage or an appropriate dose of Ipecacuanha, and immediately notify the doctor for advice and timely intervention.
4. Posthappy drug side effects
Common undesirable effects of Posthappy drugs include:
Headache, dizziness, edema, breast pain and nausea; Depression ; Amenorrhea, the menstrual pattern may be transiently disturbed, but most often begin to normalize by the next menstrual period. Less common symptoms of Posthappy include:
Weight change; Decreased sex drive; Hairy, sweaty and bald.
5. Posthappy drug interactions
Some interactions with Posthappy oral contraceptives include:
Inducers such as liver enzymes such as Barbiturates, Phenytoin, Primidon, Phenobarbiton, Rifampicin, Carbamazepine and Griseofulvin may reduce the contraceptive effect of the drug. If you are taking long-term liver enzyme inducers, you should choose another method of contraception. Concomitant use of antibiotics may reduce the effect of Posthappy by interfering with the intestinal microflora.
6. Some notes when using the drug Posthappy
Levonorgestrel must be used with caution in patients with epilepsy, valvular heart disease, cerebrovascular disease, people with increased risk of ectopic pregnancy and diabetes. Levonorgestrel can cause fluid retention, so it is important to monitor weight when using it in people with asthma. Caution should be exercised when administering Posthappy to drivers and operators of machinery. Pregnant women do not use Posthappy Women who are breastfeeding can use Posthappy because it is not harmful to nursing babies, starting 6 weeks after birth, the drug does not reduce breast milk secretion. Hopefully, the information shared about the uses, usage and some necessary notes about Posthappy will help users understand and use birth control pills effectively and safely.
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