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Obesity, overweight is a common nutritional disorder today. In addition to the right diet and exercise, patients can use additional weight loss drugs such as Odistad 120mg. So what is odistad and what should be noted when using it?
1. What is Odistad?
Odistad is a weight loss drug, the main active ingredient is Orlistat 120mg in the form of orlistat pellets 50%. At the same time, the excipients of the weight loss drug odistad 120mg also include Lactose, croscarmellose sodium, sodium stearate, sodium lauryl sulfate povidone...
Active ingredient Orlistat belongs to the group of anti-obesity agents with peripheral effects. reversible inhibition of lipase. When the drug odistad enters the stomach and small intestine, it will bind with lipase (secreted in the stomach and pancreas). This inactivates the enzyme and makes it incapable of hydrolysing fats in food into other types of fats. absorbed by the body. Unabsorbed fat reduces the amount of calories in the meal, thus providing a positive effect in weight control.
When used at a dose of 120mg / time, 3 times / day, odistad inhibits the absorption of about 30% of fat in food. Unabsorbed fat is excreted in the stool, so the amount of fat in the stool will increase for 24-48 hours after taking odistad. When discontinuation of use, the amount of fat in the stool will return to normal within 48-72 hours.
2. Effects of Odistad
Weight loss drug Odistad 120 mg is indicated for use in combination with a low-calorie/restricted diet in the following conditions:
Treatment of obesity; Prevention of weight regain in patients with a body mass index (BMI) above 30 kg/m2 or in patients with a BMI above 28 kg/m2 with risk factors such as hypertension, diabetes mellitus, disorders blood lipids.
Thuốc Odistad được sử dụng với bệnh nhân béo phì
3. Dosage and how to use Odistad
As recommended, cases of needing to treat obesity and prevent weight gain in adults need to use 1 odistad 120 mg weight loss pill, 3 times a day with fatty meals.
3.1. About how to use Odistad Take the medicine with plenty of water just before, during or 1 hour after each main meal. If the meal is not eaten or the meal is fat-free, odistad may not be necessary;
Use in excess of 3 times per day has not been shown to provide additional benefit; If there is still no effect after 12 weeks of using odistad 120mg, the patient should consult a doctor or pharmacist and may discontinue treatment. 3.2. Some notes during the use of odistad Diet and exercise still play a very important role in the weight loss program. As recommended, patients should develop a diet and exercise regimen before starting odistad; The diet needs to ensure a balance of substances, reduce calories slightly and only about 30% of calories come from fat. At the same time, the amount of fat, carbohydrates and protein should be concentrated in 3 main meals; After discontinuing odistad, the patient should still maintain a regular diet and exercise regimen; The safety and effectiveness of odistad when taken for more than 4 years have not been evaluated. In addition, safety and efficacy in children under 12 years of age have not been established; Information and data on the effects of odistad on the elderly are still limited; There is no evidence of cases of liver failure, renal failure using odistad. However, the active ingredient orlistat is very little absorbed, so the dose may not be adjusted in the elderly or in cases of liver or kidney failure. 3.3. Contraindications to the use of weight loss pills odistad 120 mg History of allergy to orlistat or other ingredients contained in the drug; Chronic malabsorption syndrome or biliary obstruction; Concomitant treatment with Cyclosporin is required; Pregnant and lactating women; Concomitant use with warfarin or other oral anticoagulants.
4. Some warnings and cautions when using Odistad
Digestive disorders : Patients should maintain appropriate nutrition because the risk of digestive disorders may be increased when odistad is used with separate meals or high in fat; Reduced absorption of fat-soluble vitamins: Active ingredient orlistat reduces the absorption of fat-soluble vitamins (including A, D, E and K), so patients need to actively take multivitamin supplements at bedtime. ; Effects of drugs to treat diabetes, hypertension or dyslipidemia: Weight loss will partly help improve blood sugar levels, blood pressure values and blood lipid levels. Therefore, the case of using drugs to treat the above diseases should consult a doctor before using odistad 120 mg weight loss drug, if necessary, the dose of the drugs can be adjusted accordingly; Amiodarone: Patients who are being treated with the heart rate control drug amiodarone should consult their doctor when using odistad; Rectal bleeding: This condition has been reported in patients using odistad. Consult your doctor if rectal bleeding occurs; Oral contraceptives: It is recommended to use additional contraception to prevent possible failure of oral contraceptives, in case of severe diarrhea; Kidney disease: It is necessary to consult a doctor before using odistad 120mg for weight loss because the active ingredient orlistat is associated with oxalateuria or oxalate kidney disease and has the potential to cause kidney failure, especially high in people with a history of kidney disease. have chronic kidney disease and/or are dehydrated; Levothyroxine: Hypothyroidism and/or decreased control of hypothyroidism may occur with the combination of odistad and levothyroxine. Therefore, patients taking levothyroxine should be discussed with if they want to use odistad, it may be necessary to take 2 drugs at different times and adjust the levothyroxine dose; Antiepileptic drugs: Patients being treated for epilepsy should be careful when taking odistad. The doctor will monitor the frequency and severity of seizures, if they are more severe consider using antiepileptic drugs and odistad at different times; HIV antiretroviral drugs: Active ingredient Orlistat may reduce the absorption of HIV antiretroviral drugs, thereby negatively affecting the effectiveness of these drugs; Odistad 120 mg weight loss pill contains lactose, so it is not recommended for patients with hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption.
Người bệnh nên thận trọng khi sử dụng thuốc Odistad
5. Undesirable effects of the drug Odistad
Influenza virus infection; Lower blood glucose; Psychiatric disorders: Anxiety, restlessness; Headache; Have an upper respiratory tract infection or a lower respiratory tract infection; Discomfort, abdominal pain, increased mucus secretion in the rectum, acute diarrhea, fatty stools, flatulence, increased frequency of defecation; Rectal pain, bowel incontinence; Disorders of teeth and gums; Rectal bleeding, appendicitis, pancreatitis; Urinary tract infections; Oxalate kidney disease, the risk of kidney failure; Irregular menstrual disorders; Gallstones, hepatitis; Blistering blisters; Increased liver transaminases and alkaline phosphatase; Decreased prothrombin, increased INR and therapeutic imbalance of anticoagulants. It can be seen that Odistad is considered a safe weight loss aid. However, this drug may not have the best effect when there is no scientific diet or it is not suitable for many subjects. Therefore, before using the product, you need to consult your doctor for safe use.
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