Mycophenolate Mofetil: Uses, indications and precautions when using

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Mycophenolate Mofetil is also known as MYCOPHENOLATE MOFETIL. The drug is prepared in the form of capsules with a weight of 250mg. This medication comes in the form of an oblong, caramel-blue capsule, printed with the words "54 848" and "54 848". The drug has an immunosuppressive effect, often used in patients who have recently received new organ transplants.

1. Uses of Mycophenolate Mofetil

Mycophenolate drugs work to keep your body from attacking and rejecting a newly transplanted organ (such as a kidney, liver, or heart), usually used in combination with certain medications. other drugs. Mycophenolate Mofetil belongs to the group of immunosuppressive drugs. This drug works by weakening your body's defense system (immune system) to help your body adapt to the new organ.

2. How to use mycophenolate mofetil

The drug mycophenolate Mofetil is taken orally. Dosage is usually twice daily on an empty stomach (1 hour before or 2 hours after a meal). When taking the medicine, swallow the tablets whole, do not crush or chew them in the mouth.
If the capsule is opened or if there is dust from the tablet, avoid inhaling the powder or dust and avoid direct contact with skin or eyes. If contact occurs, wash affected skin thoroughly with soap and water or rinse eyes with plain water.
Mycophenolate Mofetil is absorbed through the skin and lungs, so women who are pregnant or may become pregnant should not use this medicine or breathe dust from the tablets or powder from the capsules. Otherwise, it may affect the fetus.
The dose of the drug depends on the patient's health status and the body's ability to respond during treatment. In addition, for children, the dose must be based on the child's body weight.
You should strictly follow the doctor's instructions about the time to take the medicine and the dose to get the best effect for the treatment process. Do not stop taking mycophenolate without your doctor's approval. Keep using the medicine even if your body feels better.
Do not take this medicine at the same time as antacids containing aluminum and/or magnesium, cholestyramine, colestipol, or calcium-free phosphate binders (such as aluminum products, lanthanum, sevelamer). Combining them with the medicine mycophenolate Mofetil can make it harder for your body to absorb and reduce the effectiveness of the medicine.

3. Side effects

Mycophenolate has the ability to weaken the body's immune system. This means your body is more likely to get a serious infection or make any infection you have worse. However, deaths are very rare. Signs that you have some kind of infection (such as sore throat that doesn't go away, fever, chills, cough, burning or pain or urgency to urinate, change in the amount of urine).
During the use of the drug you may experience constipation, nausea, headache, diarrhea, vomiting, abdominal pain, flatulence, tremor, dizziness, or drowsiness. If these symptoms persist or worsen, take the patient to a medical facility immediately to receive prompt help from the doctor.
Some serious side effects may occur when using this medicine, including: unusual tiredness, fast or irregular heartbeat, easy bleeding or bruising, swelling of the feet or ankles. This medicine may increase your risk of a rare but very serious (possibly fatal) brain infection (progressive multifocal encephalopathy-PML). Patients need medical intervention when they have the following symptoms: clumsiness, loss of coordination or balance, weakness, sudden changes in your thinking (such as confusion, difficulty concentrating, memory loss) ), trouble speaking or walking, seizures, vision changes.
Some of the symptoms that indicate you have a serious allergic reaction include: redness, itching, swelling (especially of the face, tongue and throat), severe dizziness, difficulty breathing. However, deaths from allergies are very rare.

4. Precautions

Before taking mycophenolate mofetil, tell your doctor about any allergies you may have, especially to mycophenolic acid or sodium mycophenolate. There are some inactive substances in the ingredients that can affect your health (for example, serious side effects or allergic reactions).
Declare detailed medical history of you and your family, especially: cancer, liver disease (such as hepatitis B, hepatitis C), kidney disease, herpes or shingles diseases, stomach problems stomach or intestines, genetic disorder

Side effects of the medicine may make you feel dizzy or drowsy. With subjects using alcohol or marijuana, these symptoms will appear more severe. Do not drive or do any work that requires high concentration after taking the drug.
Since Mycophenolates weaken the body's immune system, they can make existing infections worse. Contact with patients with infectious diseases that can be spread (such as chickenpox, measles, influenza) should be limited. Absolutely do not self-inject the vaccine without the consent of the treating doctor.
Before surgery, give your doctor a list of all medications you are taking (including prescription drugs, over-the-counter drugs, and supplements).
Do not donate blood while using mycophenolate and for 6 weeks after stopping it. Pregnant women are advised not to use this medicine. It can harm an unborn baby. It is important to prevent pregnancy while taking this medicine and for 6 weeks after stopping it. Women of childbearing age, need to use a pregnancy test before each use of the drug. A reliable form of birth control should be used during treatment and for 6 weeks after stopping treatment in this case. Men with female partners of childbearing age should use reliable forms of birth control while using this medicine, especially 3 months after treatment.

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Reference source: webmd.com