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Medialeczan is a pain reliever, antipyretic of the non-steroidal anti-inflammatory group. The drug has the main ingredients Acetaminophen 325mg and Ibuprofen 200mg. For more information about the uses and indications for using Medialeczan, please read the following article.1. What disease does Medialeczan treat?
Acetaminophen helps to reduce body temperature in febrile patients and rarely lowers body temperature in normal people, because the drug acts on the hypothalamus to cause hypothermia, increased heat production due to vasodilation and increased peripheral blood flow.Active ingredient Acetaminophen or N - acetyl - p - aminophenol is an active metabolite of phenacetin, an effective analgesic and antipyretic that can replace aspirin. Ibuprofen is a propionic acid derivative with strong anti-inflammatory, analgesic and anti-inflammatory effects that appear maximum after 2 days of treatment. In addition, the drug has a mild antipyretic effect. However, because of its poor antipyretic effect, it is rarely used as a single antipyretic, but often used in combination.
The mechanism of anti-inflammatory action of Ibuprofen is to inhibit the synthesis of inflammatory chemical mediators, especially prostaglandins, by inhibiting the enzyme cyclooxygenase (COX) which is the enzyme that synthesizes prostaglandins. The drug also has mild and moderate analgesic effect by reducing the synthesis of prostaglandin F2, reducing the receptor area of sensory nerve endings with pain-causing substances of inflammatory response such as Bradykinin, serotonin...Anti-inflammatory effect platelet aggregation is weaker than aspirin. In addition, the active ingredient ibuprofen also antagonizes the proteolytic enzyme system, prevents the protein modification process to stabilize the lysosomal membrane and antagonizes the effects of chemical mediators such as bradykinin, serotonin, histamine, chemotaxis inhibition. leukocytes, inhibiting the migration of leukocytes to inflamed tissues.
Medialeczan is used to treat the following cases:
Synovial bursitis, arthritis, muscle pain Back pain, rheumatism Sports trauma Pain in dentistry, obstetrics, orthopedics. Headache, toothache, dysmenorrhea Cancer pain Fever Do not use the drug in the following cases:
Advanced liver disease, viral hepatitis or alcoholics Severe kidney failure Nasal polyps Bronchospasm Angioedema, anaphylaxis or allergy due to aspirin or other NSAID Progressive peptic ulcer
2. Dosage - How to use
Adults: take 1 tablet/time, every 4-6 hours/day, maximum dose of 8 tablets/day.
When taking an overdose of Medialeczan, patients may experience symptoms such as side effects that the drug causes, even death. Closely monitor patients who have overdosed on drugs and their manifestations, if suspected Medialeczan drug poisoning, immediately take the patient to the nearest medical facility for examination, monitoring and timely treatment.
During the course of taking Medialeczan if you forget a dose, do the following: Take the dose again as soon as possible and skip it if it is too close to the next dose. Continue to take the next dose as usual, never take a double dose to make up for the forgotten portion. Note, the dosing interval of Medialeczan should be every 4-6 hours. Except for the case that the doctor is only strict about the time of use, it is necessary to strictly follow the indications. Take the correct dose or consult your doctor before deciding to take a medicine if you have missed a dose.
3.Drug interactions
Alcohol: Do not take Medialeczan with alcohol or other alcoholic beverages. Anticoagulants, coumarins, indandion derivatives. Antihypertensive drugs, diuretics. Cardiovascular drugs: Digoxin. Diabetes medication: Insulin Gout medication: Colchicine. Other drugs: Lithium, methotrexate and probenecid.
4. Adverse effects of the drug Medialeczan
Common side effects: Stomach ulcer, hepatitis. Uncommon side effects: Dizziness, anxiety disorder, irritation or hypersensitivity, congestive heart failure, renal failure, cystitis, polyuria, atopic dermatitis, Stevens Johnson syndrome... To To ensure that Medialeczan is used safely, at the right dose, according to indications and to avoid other adverse interactions, the patient needs to follow the doctor's instructions. If you have any further questions about the drug, please consult your doctor/pharmacist for advice.
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