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The Bicarbonate test is a commonly used test to measure the electrolyte balance in the body. The reference level of the test result is around 22-26mmol/L.1. What is Bicarbonate Test?
Bicarbonate is a biochemical test used to measure the total amount of bicarbonate in the blood. Bicarbonate is a negatively charged ion that is excreted and reabsorbed by the kidneys. The effect of bicarbonate is to help the body balance PH in the body with sodium, potassium and chloride.If the results of the bicarbonate (alkaline reserve) test are in the range of 22-26mmol/L, the body has a safe electrolyte balance. If the test reading is lower or higher than the reference range, the body has not reached electrolyte balance and can be a sign of dysfunction.
Causes of low bicarbonate levels, can be because you are suffering from some diseases such as addison's disease, chronic diarrhea, diabetic ketoacidosis or metabolic acidosis, patients with kidney disease, methanol poisoning or due to overdose of aspirin,... some drugs also work to make your Bicarbonate test results drop like thiazide diuretics, methicillin,...
Causes of increased test index Bicarbonate testing can be caused by vomiting, lung disease, cushing's syndrome, Conn's syndrome, and metabolic alkalosis. In addition, some drugs also work to increase your Bicarbonate test results such as cyclic diuretics, steroid drugs,...
Xét nghiệm Bicarbonat giúp đo lường tổng lượng bicarbonat có trong máu
2. Indications for use of the Bicarbonate test
Bicarbonate test is commonly used in the following cases:Used together with potassium, sodium and chloride tests indicated as one of the important tests in the evaluation of chronic or acute diseases. Used in the monitoring of chronic diseases such as high blood pressure Used to evaluate the results of the treatment process Assess the degree of electrolyte imbalance in the body and determine the cause of the weight loss with electrolytes Bicarbonate test is often used in the following subjects:
Patients with periodic blood monitoring Who is suspected of water retention or dehydration Patients who need to be evaluated for electrolyte balance and the cause of the loss electrolyte balance.
3. What is Bicarbonate (HCO3-)?
Bicarbonate is the amount of HCO3 present in plasma, which includes true bicarbonate (actual bicarbonate = AB) and standard bicarbonate (standard bicarbonate = SB).True bicarbonate is an indicator of the actual concentration of bicarbonate in a blood sample taken under non-air conditions, it corresponds to the true pH and PaCO2 of the blood sample.
Normal: AB = 25 mmol/l. Standard bicarbonate is the index of the amount of HCO3- (mmol/l) of a plasma sample that has been reduced to standard conditions such as PaCO2= 40 mmHg, To= 37oC, pH = 7.40. Normal values are in the range SB = 24 ± 2 (mmol/l).
Bệnh nhân theo dõi máu định kỳ thường làm xét nghiệm Bicarbonat
4. Acid-base balance disorder
There are 3 groups of acid-base disorders: disorders caused by respiratory causes (due to changes in PaCO2), disorders due to metabolic causes (due to changes in HCO3_) and mixed disorders due to both metabolic and biological causes. respiratory causes.In clinical assessment of electrolyte imbalance, we can use Shneerson, Siggar Anderson, Davenport diagram, in which Davenport diagram is used more. There are 6 areas of acid-base imbalance on the Davenport diagram including respiratory acidosis, metabolic alkalosis, respiratory alkalosis, metabolic acidosis, mixed acidosis, and mixed alkalosis.
Thus, it can be seen that the Bicarbonate test (alkaline reserve) has great significance in the diagnosis and treatment of diseases. For accurate test results, you should choose reputable and good quality medical facilities to give accurate assessment results.
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