This is an automatically translated article.
Posted by Pharmacist Nguyen Thi Bich Phuong - Clinical Pharmacist - Faculty of Pharmacy - Vinmec Ha Long International Hospital
The drug has the active ingredient enoxaparin sodium which has anticoagulant effect and some other benefits. To ensure effective treatment, patients need to strictly follow the instructions of the doctor, pharmacist advising on the use of the drug.
1. Ingredients and uses of Lovenox
Lovenox has the active ingredient enoxaparin sodium, which is a low molecular weight heparin with anticoagulant effect. Lovenox is indicated in the following cases:Prophylaxis of venous thromboembolism in surgery with moderate or high risk. (Example: Knee, hip, or other surgery when the risk of venous thromboembolism is associated with the type of surgery (especially cancer surgery) and/or with increased patient involvement forward). Prophylaxis of deep vein thrombosis in bedridden patients with certain acute medical conditions: heart failure, acute respiratory failure, acute bacterial infection or acute rheumatic disorder associated with significant increased risk factors for thrombosis clear. Prevention of blood clotting in the extracorporeal circulation during dialysis. In addition, the drug is also prescribed by doctors on pregnant women in some special cases.
2. How to take Lovenox
The drug is administered subcutaneously except for the prevention of blood clots in the extracorporeal circulation during dialysis. However, Lovenox is contraindicated for intramuscular administration.
3. Some cases should not use Lovenox medicine and notes when using it
3.1. Contraindications to the use of Lovenox
The following cases are contraindicated to the use of Lovenox:
Allergy to preparations containing heparin or heparin derivatives including other low molecular weight heparins. The patient has a history of severe heparin-induced thrombocytopenia. Blood clotting disorder. Bleeding or risk of uncontrolled bleeding.
Bệnh nhân rối loạn động máu nên cân nhắc dùng lovenox 40mg
3.2. Who should not use the drug for?
The following subjects are often recommended by doctors not to use the drug:
Severe kidney failure. The first 24 hours after cerebral hemorrhage Over 65 years of age, taking in combination with aspirin (at analgesic and antipyretic doses), NSAIDs, Dextran. To avoid bleeding, it is important that the patient does not exceed the dose prescribed by the doctor. In addition, patients need to have their platelets monitored periodically while taking the drug. Accordingly, caution should be exercised when using the drug in the following subjects:
Elderly patients. Weight less than 40 kg Renal failure Patients taking in combination with some drugs that increase the risk of bleeding (aspirin, NSAIDs, dextran, oral anticoagulants...)
4. Lovenox side effects
Besides the therapeutic effect, Lovenox medicine can leave some side effects as follows:
Internal or external bleeding of different severity. In this case, the doctor should be informed immediately. Thrombocytopenia in the blood, in some cases can have serious consequences. Severe skin reactions are rare at the injection site. More commonly, there may be bruising or hematoma under the skin at the injection site. Local or systemic allergic reactions. Risk of osteoporosis with prolonged treatment. In addition, there are other side effects such as: Increased liver enzymes, hyperkalemia, eosinophilia, nerve damage in some anesthetic procedures...
Lovenox is indicated for the prevention of embolism Intraoperative venous thromboembolism at moderate or high risk. To ensure the effectiveness of treatment, drug users need to use drugs according to prescription or under the direction of a doctor or pharmacist.
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References:
SPC Product Information Sheet
