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Trajenta is a drug containing the active ingredient linagliptin, which is used in the treatment of type 2 diabetes, helping to control blood sugar well for patients. In addition, the drug can be prescribed as monotherapy or in combination with other hypoglycemic agents.1. Uses of the drug Trajenta
Trajenta is a drug containing the active ingredient linagliptin, commonly used in the treatment of type 2 diabetes. To control blood sugar for patients, the drug can be prescribed alone or in combination with other hypoglycemic agents. Trajenta drug is effective in the treatment of the following cases:
The patient has not well controlled blood sugar by diet and exercise. Patients are not suitable for treatment with metformin due to intolerance or contraindications due to renal failure. In addition, Trajenta is also used in combination therapy with:
In combination with metformin with the brand name Trajenta duo when diet, exercise and metformin monotherapy do not provide good control of blood sugar. Combination with sulfonylurea or pioglitazone when the patient does not respond well to the treatment regimen. The 3-drug combination regimen of Trajenta, metformin and a sulfonylurea when the two-drug regimen is not effective for the patient. Combination with insulin may or may not be combined with metformin when the combined treatment regimen with diet and exercise does not help control blood sugar.
2. How to use Trajenta
Trajenta is prepared in the form of film-coated tablets with a strength of 5mg. Dosage is divided according to each subject as follows:
For adults, the maximum recommended daily dose should not exceed 5mg of linagliptin. It is necessary to select the appropriate dose based on the current treatment regimen in combination with other active ingredients, effectiveness and tolerability of the drug in each patient. No dose adjustment is necessary for patients with hepatic impairment, renal impairment and the elderly. For children: According to research, Trajenta's use in children has not been fully reported. Therefore, the drug is not recommended for use in children under 18 years of age. Besides, if you use the tablet form, you should take it with food or with a meal, do not crush, break or chew the tablet. You should swallow the tablet whole with a certain amount of water. For injectable drugs, it will be done with medical staff and can be given intravenously or intramuscularly. Use Trajenta exactly as directed by your doctor, do not use more, smaller or longer than prescribed. Trajenta can be taken with or without food or as directed by your doctor.
Use Trajenta regularly to get the most benefit from it and can stop taking it if any new signs of abnormality appear or the condition does not improve after 7 days. Absolutely do not abuse the drug for too long for a long time. This does not make the patient's condition better, but also increases the risk of unwanted effects.
3. Undesirable effects when using Trajenta
Trajenta may cause some unwanted side effects. But most people who use Trajenta usually don't experience any serious side effects. A common condition is low blood sugar after taking the drug. Trajenta monotherapy is unlikely to cause an excessive decrease in blood sugar, however this can occur when used in combination with other antidiabetic drugs or with an inappropriate diet. . Some early warning signs of low blood sugar such as:
Fatigue Trembling Feeling of hunger Sweating Confusion Difficulty concentrating Besides, some side effects that may be experienced after using Trajenta include include:
Cough Nasopharyngitis Hypersensitivity: angioedema, rash, urticaria Weight gain Constipation Pancreatitis Before prescribing the drug, the doctor always considers the benefit and effectiveness that Trajenta drug when taking Trajenta may still occur. produce undesirable effects. Therefore, when unusual symptoms appear, especially when a severe allergic reaction occurs with accompanying signs such as severe dizziness, difficulty breathing, rash, swelling or itching of the face and throat. , tongue, ... In this case, the patient should immediately notify the doctor or nurse for immediate medical intervention.
4. Some notes when using Trajenta
Some notes when using Trajenta include:
Report a history of allergy to Trajenta or any other allergies. Trajenta may contain ingredients that don't work and could cause an allergic reaction or other serious problems. Notice the medications you are taking including prescription, nonprescription, herbal and dietary supplements. For women who are pregnant, planning to become pregnant in the near future or are breast-feeding, it is necessary to note the use of Trajenta. Contraindicated for patients with type 1 diabetes, caused by the body's inability to produce insulin, insulin deficiency, diabetic ketoacidosis, allergy or hypersensitivity to any ingredient. part of the drug. Trajenta should be used with caution in patients with pancreatitis or those with a history of pancreatic problems, who have low blood sugar. The possibility of hypoglycemia after using Trajenta may be increased if you have an unhealthy diet and lack of nutrients. In addition, alcohol is also one of the causes of low blood sugar, especially when drinking heavily and skipping meals. Therefore, during the treatment, make sure that all meals are complete, do not starve or skip meals. In case you plan to exercise more often than usual, you should eat carbohydrates such as bread, cereal, pasta before, during and after exercise. If you forget to take a dose of Trajenta, take it again as soon as possible. However, if it's almost time for your next dose, skip the missed dose and continue taking it as scheduled. Based on controlled clinical studies in healthy subjects, single doses of Trajenta up to 600 mg equivalent to 120 times the recommendation have been well tolerated. However, the potential risk associated with its use has not yet been determined. Do not take more medicine than prescribed. Trajenta overdose or ingestion can cause serious symptoms such as nausea, vomiting, abdominal pain, difficulty breathing, fainting,...
5. Drug interactions
Drug interactions can reduce the effect of Trajenta, or increase the effect of unwanted effects. Tell your doctor about all other medicines you are taking including over-the-counter medicines, vitamins, prescription drugs, and herbal products. Do not start, stop or change the dose of any medicine without your doctor's consent.
Drugs that can interact with Trajenta include:
Insulin or sulphonylureas antidiabetic drugs, eg glimepiride and glipizide, need to adjust the dose when combined to avoid causing too low blood sugar level. The anti-tuberculosis drug rifampicin
6. How to store Trajenta
Store Trajenta at a temperature not exceeding 30°C, protected from light and away from moisture. Do not store Trajenta in a humid place or in the freezer and keep away from heat and open flames. Different medicines will have different storage methods, so read Trajenta's storage instructions carefully on the packaging, or ask your pharmacist. Keep Trajenta out of the reach of children and family pets. When the medicine has expired or is damaged and cannot be used anymore, dispose of it and dispose of it properly. Do not arbitrarily dispose of Trajenta into an environment such as a water pipe or toilet unless requested to do so. Please consult your waste disposal company or pharmacist on how to safely dispose of Trajenta to help protect the environment. In short, Trajenta is a drug containing the active ingredient linagliptin, which is used in the treatment of type 2 diabetes, helping to control blood sugar well for patients. In addition, the drug can be prescribed as monotherapy or in combination with other hypoglycemic agents. However, Trajenta can cause some unwanted effects and drug interactions, so tell your doctor what medicines you are taking to reduce the risk of unwanted effects and at the same time increase effective for treatment.
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