Isradipine: Uses and dosages

This is an automatically translated article.

Isradipine is a calcium channel blocker antihypertensive drug of the dihydropyridine class. Calcium channel blockers on voltage-dependent L-type channels in arterial smooth muscle are more effective than those in cardiomyocytes.

1. Pharmacological information of the drug isradipine

Active ingredient : Isradipine
Class: Calcium channel blocker/antihypertensive
Legal group: ETC - (Ethical drugs, prescription drugs, Prescription only medicine)
ATC code (Anatomical Therapeutic Chemical): C08CA03.
Brand name: Dynacirc.
Generic : Isradipine
Dosage form – Content:
Capsules: 2.5 mg and 5 mg. Tablets: 2.5 mg. Slow-release tablets: 5 mg, 10 mg

2. What are the uses of Isradipine?

Isradipine works by helping the heart muscles and blood vessels to relax, especially the arteries in the brain and skeletal muscles, without impairing heart function, without having to work too hard, so it is usually prescribed by doctors. in the treatment of high blood pressure.
Regular use of medication helps control blood pressure and minimize possible serious complications. Isradipine can be used in combination with other antihypertensive drugs. The drug can also be used to treat other diseases as prescribed by your doctor.

3. Instructions for using the drug Isradipine

Dosage of Isradipine for adults: 2.5 mg at first, twice a day. Your doctor may increase your dose if necessary.
Use the initial dose with 2.5 mg / day, divided equally into 2 doses. The dose can then be increased if necessary. However, you should consult with your doctor or pharmacist before you intend to increase the dose. The manufacturer has not studied the safe dosage as well as the benefits of the drug for the group of children. In case of need to use medicine for children, it is necessary to consult a doctor.

4. What are the side effects when taking Isradipine?

Isradipine medicine can cause unwanted effects for patients such as:
Irregular, fast and difficult to control heartbeat. The body feels extremely tired. Digestive disorders: abdominal pain, nausea, vomiting, loss of appetite. There may be diarrhea. Frequent headaches and dizziness. Some side effects are more serious but very rare
Skin rash . Chest tightness, difficulty breathing. Swollen eyes, lips, tongue, hands or feet. In some cases, the patient may also have unusual fainting. To minimize possible side effects, users should absolutely follow the instructions and indications on how to use the drug in the treatment of the disease.

5. Precautions before taking Isradipine

In order to use Isradipine to achieve the best effect, people need to carefully pay attention to a few issues as follows:
Before using, should discuss with your doctor, do not arbitrarily use the drug if not approved. prescribed by doctors. Before taking this drug, you need to make a complete list of the drugs you are taking including functional foods, vitamins, herbs, herbs...so that the doctor can know from which to prescribe and review to refer to. determine the appropriate dose of the drug. Use extreme caution if you are allergic to any of the ingredients in Isradipine or are sensitive to any of the ingredients in other medicines. Care should be taken when administering Isradipine when administering Isradipine to children or the elderly. Talk to your doctor if you have ever had an intestinal blockage. Use the drug strictly according to the instructions and instructions of the doctor for patients with diseases related to arrhythmia, such as heart failure, heart valve regurgitation. Patients must absolutely not change the dosage or prolong the duration of the drug without consulting the doctor. Take the drug by drinking with a full glass of water, the drug is in capsule form, so it should be swallowed whole, not chewed, crushed, or bitten because it will affect the effect of the drug. Isradipine should be maintained and taken at a certain time of the day to avoid missed doses and should be taken before or after meals. Patients should continue to use the drug and do not stop the dose even if the blood pressure has stabilized and symptoms such as headache and dizziness have gradually disappeared. While taking the medicine you need to regularly measure your blood pressure to see if the correct Isradipine is working.
Because Isradipine can make users dizzy, it is important to drive carefully after taking the drug. Do not drink alcohol, smoke or use heavy stimulants while using Isradipine. In addition to you using this medicine properly, people also need to have a good way to control their weight, avoid being overweight, obesity or other problems by changing their diet. People can ask a doctor for advice on the most scientific eating problem.
In case the user has liver failure, heart failure, kidney failure or the subject is the elderly, the dosage should be adjusted. Patients who have sinus node syndrome or are suspected of having but not able to place pacing blood should consult their physician if they intend to use drugs in their treatment. Women who are pregnant or breastfeeding should weigh the benefits and risks of harm before taking the drug. To avoid harm to the health of children and unborn babies.

6. Isradipine should not be used with which drugs?

Isradipine has the potential to interact with some other drugs, if used at the same time, drug interactions will increase side effects that affect health. Some drugs will interact with Isradipine, such as:
Fentanyl : Anesthetic pain reliever Cimetidine: Medicines to treat stomach ulcers Antibiotics used to prevent tuberculosis: Rifampicin Medicines Itraconazole Carbamazepine and Phenytoin: These two drugs are often prescribed by doctors for patients who have frequent seizures or have epilepsy Rifabutin : commonly prescribed by doctors to treat some common bacterial infections such as tuberculosis, leprosy, ... Phenylephrine, Pseudoephedrine, Naproxen, Ibuprofen: These are non-steroidal anti-inflammatory drugs (NSAIDs).

7. How should Isradipine be stored?

Usually, the dosage forms of Isradipine only need to be stored at room temperature, away from moisture and away from light. Do not store in the bathroom or refrigerator. Remember to keep the medicine out of the reach of children and pets.
When overdosing or experiencing unwanted effects of the drug should notify the doctor or immediately go to the nearest medical facility for appropriate diagnosis and treatment plan.
Customers can directly go to Vinmec Health system nationwide to visit or contact the hotline here for support.

See more:
Benefits of buying medicine at Vinmec Hospital Pharmacy System Launching Vinmec Medicine Manual 2019 Using drugs safely