Indications for H.Pylori test in children and non-invasive diagnostic methods

This is an automatically translated article.

The article was written by Specialist Doctor II Bui Thu Huong - Head of Emergency, Day Treatment Unit, Pediatric Center - Vinmec Times City International Hospital.

HP test is indicated to perform when the patient has peptic ulcer with persistent signs, unusually severe progression. After treatment, the HP test is repeated to check whether the patient is completely cured or not.

1. Indications for testing for H.Pylori in children


Recurrent abdominal pain is not an indication for testing for H. pylori infection. Children with gastrointestinal symptoms should be excluded from other causes before testing for H. pylori infection is indicated. Iron deficiency anemia has no known cause. Autoimmune thrombocytopenic purpura of no known cause.

Trẻ thường xuyên đau bụng cần được làm xét nghiệm H.Pylori
Trẻ thường xuyên đau bụng cần được làm xét nghiệm H.Pylori

2. Non-Intrusive Diagnostic Methods


2.1 Serum Methods: Enzyme-linked immunosorbent assay (ELISA), Latex agglutination, Immunoblot (IM) Sensitivity: 83 – 99% Specificity: 79.2% - 92.4% Advantages: − Cost low
− Does not cause discomfort to the patient, can be used in young children
− Allows epidemiological studies to be conducted
Disadvantages − Cannot differentiate between new H. pylori infection or previous infection
− Degree of infection Accuracy of the test varies according to different commercial kits

Phương pháp chẩn đoán không xâm nhập bằng xét nghiệm huyết thanh
Phương pháp chẩn đoán không xâm nhập bằng xét nghiệm huyết thanh

2.2 Breathing test (UBT) Is an accurate method applied in diagnosis and treatment monitoring Is the gold standard for diagnosing H. pylori infection in non-endoscopic conditions Sensitivity: 96% - 98% Specificity : 96% - 99% The accuracy of breathing test is reduced if the patient takes PPIs, bismuth, antibiotics within 4 weeks before the test Advantages: does not cause discomfort to the patient, assesses the condition of the patient. bacterial infection, high sensitivity and specificity Disadvantages: C14UBT has radioactivity, C13UBT is expensive
2.3 Fecal antigen detection test Is as accurate as a breathing test for diagnosis and treatment monitoring Recommended for monitoring and treatment of H. pylori infection Sensitivity: 94% - 99 % Specificity: 94 - 97% Advantages: no discomfort to the patient, assessment of the status of bacterial infection, high sensitivity and specificity Cons: Expensive, mainly applied in research When babies have symptoms of abdominal pain, vomiting, bloating... they must go to the hospital to be diagnosed with the disease, do not self-treat.

Phương pháp test phát hiện kháng nguyên trong phân
Phương pháp test phát hiện kháng nguyên trong phân

Vinmec International General Hospital is one of the hospitals that not only ensures professional quality with a team of leading medical doctors, modern equipment and technology, but also stands out for its examination and consultation services. comprehensive and professional medical consultation and treatment; civilized, polite, safe and sterile medical examination and treatment space. Customers when choosing to perform tests here can be completely assured of the accuracy of test results.
Customers can directly go to Vinmec Health system nationwide to visit or contact the hotline here for support.
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