This is an automatically translated article.
Crestor 5mg medicine is often used mainly to support the treatment of blood lipids, dyslipidemia or risk of stroke,... During the use of Crestor 5mg, patients should do it properly. instructions given by the doctor to maximize the effectiveness of treatment
1. What is Crestor 5mg?
Crestor 5mg drug belongs to the group of cardiovascular drugs, which is considered an effective solution to help reverse dyslipidemia, blood fat and improve the risk of stroke, stroke or myocardial infarction due to high blood fat. Crestor 5mg is a product of IPR Pharm Inc - USA, produced in the form of film-coated tablets and packaged in boxes of 2 blisters x 14 tablets.Crestor 5mg is a prescription drug, so patients are absolutely not allowed to use the drug without a prescription. In each Crestor 5mg tablet contains the following main ingredients:
Main active ingredient: Rosuvastatin calcium 5mg. Other excipients: Microcrystalline cellulose, Lactose monohydrate, Crospovidone, Magnesium stearate, Calcium phosphate, Hypromellose, Glycerol triacetate, Lactose monohydrate, yellow/red iron oxide (E172) and Titanium dioxide (E171).
2. What are the effects of Crestor 5mg?
2.1. Uses of the drug Crestor 5mg Active ingredient Rosuvastatin calcium acts as a selective and competitive inhibitor of HMG-CoA-reductase, which works to lower blood cholesterol levels for any patient of any age, gender, or age. gender or race. Even, Rosuvastatin calcium has the ability to reduce blood cholesterol even in people with diabetes, increased blood cholesterol levels with familial factors or with increased triglycerides. According to research, Rosuvastatin calcium has the effect of increasing the number of LDL receptors on the surface of liver cells, thereby increasing the absorption and catabolism of LDL, while inhibiting the synthesis of VLDL in the liver. Thanks to this effect, the components of LDL and VLDl are reduced. Approximately 5 hours after oral administration, Rosuvastatin calcium will reach peak plasma concentrations and absolute bioavailability of about 20%. The active ingredient Rosuvastatin calcium in Crestor 5mg is distributed mainly in the liver and is mainly bound to albumin. The major metabolites of Rosuvastatin calcium are Lactose and N-desmethyl. Approximately 10% of Rosuvastatin calcium will be metabolised via CYP 2C9 and to a small extent via 3A4, 2C19 and 2D6.
2.2. Indications for use of the drug Crestor 5mg Crestor 5mg is usually indicated for use in the following cases:
Treatment of primary hypercholesterolemia (type IIa) and mixed dyslipidemia (type IIb): Crestor 5mg drug indicated as adjunctive therapy for patients who have not responded adequately to diet and other non-pharmacological approaches, such as weight loss or exercise. Treatment of primary dyslipidemia (type III): Crestor 5mg is indicated as an adjunct to diet for patients being treated for primary beta-lipoproteinemia. Indicated as adjunct to diet for patients with hypertriglyceridemia (for adults). Treatment of homozygous familial hypercholesterolemia, dietary support and some other lipid-lowering measures such as LDL apheresis. Treatment of heterozygous familial hypercholesterolemia in pediatric patients aged 10 to 17 years. Adjunct to diet, which slows the progression of atherosclerosis in adults and serves as part of a therapeutic strategy to lower total cholesterol as well as LDL-C. Indication of Crestor 5mg for primary prevention of cardiovascular disease. Reduced risk of stroke, myocardial infarction, and risk of coronary revascularization procedures. 2.3. Contraindications to the use of Crestor 5mg Do not use Crestor 5mg in the following cases:
Patients with hypersensitivity or allergic reactions to Rosuvastatin ingredients or any other excipients of the drug. Patients with unexplained persistent elevations in serum transaminases, elevations of transaminases to 3 times the upper limit of normal, and patients with advanced liver disease. Crestor 5mg is contraindicated in patients with severe renal impairment, liver failure, muscle diseases or taking Cyclosporin. Do not use Crestor 5mg for pregnant and breastfeeding women.
3. Dosage and how to use Crestor 5mg
3.1. Dosage of Crestor 5mg The following is the recommended dose of Crestor 5mg by the doctor:
Initial dose: Take 15 to 10mg/time/day. After about 4 weeks of treatment consider increasing the dose as prescribed by the doctor and closely monitor the body's response, especially the muscle system. Dose for people with high blood cholesterol levels due to familial factors: Adjust the dose gradually to 40mg/day and monitor the body's response. Dose for pediatric patients aged 10 - 17 years with high blood cholesterol levels due to heterozygous age: Take 5 - 20mg/day. Dose for pediatric patients under 8 years of age with homozygous hereditary elevation of cholesterol and impaired renal function: It is necessary to consult a doctor carefully about the dosage before using Crestor 5mg. Dose for the elderly (> 70 years old): Take 5mg / time / day. In addition, Crestor 5mg is also applied in multi-therapy, specifically:
Combine Crestor 5mg with Gemfibrozil: Take the initial dose of 5mg / time / day, the maximum dose should not exceed 10mg. Combination Crestor 5mg with Lopinavir, Ritonavir or Atazanavir: Initial dose of 5mg once daily and not to exceed 10mg. 3.2. Instructions for use of the drug Crestor 5mg Crestor 5mg is made in the form of tablets that should be taken orally. Before starting treatment with Crestor 5mg, patients should follow a standard diet to lower blood cholesterol and must continue to maintain that regimen for the duration of treatment.
Crestor 5mg can be used at any time of the day, patients can take it during or away from a meal depending on individual needs. During treatment, the patient should follow all instructions given by the doctor to ensure safe and effective use of the drug.
4. Possible side effects when taking Crestor 5mg
When treating with Crestor 5mg, patients may experience some of the following adverse effects:
Neurological symptoms: Dizziness, headache, memory loss, polyneuropathy, sleep disturbance ( nightmares, insomnia), peripheral neuropathy or cognitive impairment. Gastrointestinal symptoms: Constipation, abdominal pain, nausea, diarrhea or pancreatitis. Immune system symptoms: Hypersensitivity reactions or angioedema (rare). Psychiatric symptoms such as depression. Endocrine symptoms such as diabetes. There is a risk of dyspnea or cough on the respiratory system, mediastinum and thorax. Skin or subcutaneous tissue manifestations such as rash, pruritus, urticaria or Steven-Johnson syndrome. Musculoskeletal, skeletal and connective tissue symptoms such as rhabdomyolysis, myopathy, myalgia, arthralgia, tendon injury, or immune-mediated myopathy. Systemic reactions such as asthenia. If any side effects appear during the use of Crestor 5mg, the patient should notify the doctor soon for support and treatment.
5. Things to keep in mind when using Crestor 5mg
5.1. What precautions should be taken while using Crestor 5mg Tablet? Care should be taken when administering Crestor 5mg to the following subjects:
Patients with hypothyroidism, impaired renal function or a history of myopathy due to previous use of Fibrates or Statins. The patient has a personal or family history of hereditary myopathy. The patient has a history of heavy drinking or liver disease. Elderly people have rhabdomyolysis factors. Children < 8 years old. Patients with conditions that increase Crestor 5 mg plasma concentrations. Patient is taking Fibrate. In case the patient has severe muscle reactions or has a CK index greater than 5 x ULN, Crestor 5mg should be discontinued immediately. If you have removed the outer packaging of the medicine, it should be used immediately, to avoid watery or moldy medicine. In addition, patients should also read the instructions carefully before starting Crestor 5mg to minimize the risk of side effects.
5.2. Interactions with other drugs Below is a list of drugs that may interact with Crestor 5mg at the same time, including:
Gemfibrozil. Cyclosporin drug. Coumarin anticoagulant. Protease inhibitor. Fenofibrate drug. Niacin drug. Colchicine drug. Ezetimibe drug. Erythromycin . Antacids. Ideally, when using Crestor 5mg, patients should tell their doctor a list of drugs currently taking for specific advice.
Above is all information about uses, dosage and notes when using Crestor 5mg medicine. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Crestor 5mg exactly as directed by your doctor.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
