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Adcetris 50 mg is an anticancer drug, made up of a monoclonal antibody that binds to a substance to kill cancer cells. Currently on the market there is a lot of information about the drug Adcetris 50 mg but it is still incomplete. To better understand the drug Adcetris, let's learn more in the article below.
1. What is Adcetris 50 mg?
Adcetris 50 mg (brentuximab vedotin) is a cancer medicine that interferes with the growth and spread of cancer cells in your body. Adcetris-Brentuximab Vedotin is an antibody drug conjugate (ADC) that binds to CD30-expressing cells leading to selective apoptotic cell death in CD30-expressing tumor cells.
2. What are the effects of Adcetris?
Adcetris is indicated in adult patients with previously untreated stage IV 30+ Hodgkin lymphoma in combination with doxorubicin, vinblastine and dacarbazine. Adcetris is indicated for the treatment of adult patients with CD30 + HL at risk of relapse or progression following autologous stem cell transplantation. Adcetris is indicated in the treatment of adult patients with relapsed or CD30+ Hodgkin lymphoma It is indicated in the treatment of adult patients with recurrent or refractory systemic anaplastic large cell lymphoma. Adcetris is indicated in the treatment of adult patients with CD30+ T-cell lymphoma (CTCL) after at least 1 prior systemic therapy.3. Dosage and how to use Adcetris effectively
3.1. How to use Adcetris is given as an intravenous infusion. Adcetris is usually given every 2 to 3 weeks. You may be given other medicines to help prevent serious side effects or allergic reactions. Keep taking these medicines until your doctor has prescribed them. Brentuximab vedotin can cause your blood cell count to drop. Your blood will need to be tested often. Your cancer treatments will likely be delayed based on the results. The dose of Brentuximab vedotin is based on weight. Your dosage needs will likely change if you gain or lose weight. If the patient needs surgery, tell the surgeon that you are currently taking this medicine. 3.2. Dosage Usual Adult Dose for Lymphoma:
Initial dose: 1.8 mg/kg IV over 30 minutes every 3 weeks Maximum dose: 180 mg IV over 30 minutes every 3 weeks until disease progression or unacceptable toxicity. When you miss a dose, don't worry. Usually medications can be taken within 1 to 2 hours of what is prescribed in the prescription. Unless there is a strict rule about the time of use, it is possible to take the medicine after a few hours of forgetting. However, if the time is too far from the time you need to drink, you should not take the supplement, which can be dangerous for the body. It is important to follow it properly or consult your doctor before you make a decision.
4. Adcetris 50 mg side effects
Adcetris 50 mg may cause some allergic reactions such as: rash, difficulty breathing, swelling in the face or throat, red or purple skin rash that spreads and causes blistering and peeling). Some side effects may occur during the injection or within 24 hours afterwards: dizziness, nausea, chills or fever, or if you have itching. Brentuximab vedotin can cause serious brain infections that can lead to disability or death. Call your doctor right away if you have problems with speech, thinking, vision, or muscle movement. These symptoms will likely start gradually and get worse quickly. Also, call your doctor if you have any of the following serious side effects, even if they occur several months after you take Adcetris:Numbness, weakness, burning pain, tingling, or loss of feeling in your arms or legs; sudden chest pain or discomfort, wheezing, dry cough, and feeling short of breath; Pain or burning when you are urinating; High blood sugar - increased thirst, increased urination, dry mouth, fruity breath; Ketoacidosis (too much acid in the blood) including nausea, vomiting, stomach pain, confusion, unusual sleepiness or trouble breathing Low blood cell counts: fever, chills, fatigue, mouth sores, sores skin ulcers, easy bruising, unusual bleeding, pale skin, cold hands and feet,.. Signs of tumor cell breakdown - confusion, weakness, muscle cramps, nausea, vomiting, fast heartbeat or slow, decreased urination, tingling in the hands and feet or around the mouth; Liver problems such as loss of appetite, stomach pain (upper right), fatigue, This is not a complete list of side effects and others are possible. Call your doctor right away for medical advice about side effects.
5. Notes before taking Adcetris 50 mg
You should not be treated with Adcetris if you are allergic to brentuximab vedotin, or if you are also receiving another cancer medicine called bleomycin. To make sure Adcetris is safe for you tell your doctor if you have ever had: Diabetes; Liver failure; Kidney disease; Peripheral vascular disease, such as Raynaud's syndrome.
Both men and women using this medicine should use effective birth control to prevent pregnancy. Brentuximab vedotin can harm an unborn baby or cause birth defects if the mother or father is using this medicine.
Continue to use birth control for at least 6 months after your last dose of Adcetris. Tell your doctor right away if pregnancy occurs while the mother or father is using this medicine.
6. What other drugs will affect Adcetris?
Other drugs may interact with brentuximab vedotin, including prescription and over-the-counter medicines, vitamins, and herbal products. Talk to your doctor about all of your current medications and any you start or stop using.
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