HBeAb test in the diagnosis of hepatitis B

This is an automatically translated article.

Hepatitis B is now very common and highly contagious. To accurately diagnose the course and extent of hepatitis B, it is necessary to have HBeAg and HBeAb tests.

1. HBeAb . test

HBeAb is a test to assess whether a patient infected with hepatitis B has viral activity if HBeAg Hepatitis B) is positive, on the other hand, also evaluate seroconversion after a period of hepatitis B treatment. If HBeAb is negative before, HBeAb positive after treatment indicates seroconversion.
HBeAb seroconversion occurs when HBeAb changes from (–) to (+) and HBeAg from (+) to (–). This phenomenon reflects the reduction or cessation of viral replication. HBeAb seroconversion can occur spontaneously (approximately 10%-15% per year) or seroconversion is accelerated by antiretroviral therapy.
However, some patients have had HBeAb seroconversion but HBeAg may re-emerge during episodes of hepatitis B reactivation. This phenomenon can occur in men who are homosexual, or receive chemotherapy for cancer, or receive corticosteroids.
In chronic hepatitis B, the presence of HBeAb indicates that the disease has progressed for a relatively long time, especially if it has progressed to cirrhosis, or primary liver cancer.
To understand their disease status as well as monitor the progress of the disease, patients should check their liver status and do tests to check the activity of the virus every 3 to 6 months, re-examination. periodically to see if medication is needed to treat it, to avoid serious illness that can cause bad complications.
The HBeAb test is important for early identification of potentially serious liver complications

2. How to take samples

Draw 2mL of venous blood into a tube without anticoagulant or tube with anticoagulant including: Li, Na, NH4- Heparin and K3- EDTA. The blood does not have broken red blood cells.
After blood collection, centrifuge at 4000 rpm for 5 minutes to separate serum or plasma.
Specimen is stable for 5 days, stored at 2 - 8°C, for 3 months at -20°C.
Specimens are thawed only once and must be allowed to reach room temperature before analysis. To avoid evaporation, samples, standards, and quality control substances should be analyzed within 2 hours.

3. Carrying out the technique

The analyzer needs to be ready to perform sample analysis: The meter has been calibrated with the Anti-HBe test, the quality check results with the successful Anti-HBe test are not out of range and do not violate quality control violations.
Staff performing sample analysis enter data about patient information and order tests into the analyzer or network system. Load the specimen into the analyzer. Instruct the machine to perform the analysis of the patient sample. Wait for the analyzer to analyze the sample according to its protocol. When the results are available, it is necessary to review and evaluate the results, then print the test results sheet to return to the patient.

4. What does the HBeAb . test mean?

When a person has chronic hepatitis B, the presence of HBeAb indicates that the disease has been developing for a long time. The disease may even have progressed to cirrhosis, or primary liver cancer. These are extremely dangerous complications of hepatitis B that need to be detected early.
Therefore, the HBeAb test is very meaningful in early identification of the possibility of serious liver complications when the patient has hepatitis B.
Vinmec International General Hospital is one of the diseases. The hospital not only ensures professional quality with a team of leading medical professionals, a system of modern equipment and technology, but also stands out with comprehensive and professional medical examination, consultation and treatment services; civilized, polite, safe and sterile medical examination and treatment space. Customers when choosing to perform tests here can be completely assured of the accuracy of test results.

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