Haegarda drug: Uses, indications and notes when using

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Haegarda drug is produced from human plasma, which works to control swelling in the body in patients with hereditary angioedema.

1. What are the effects of Haegarda?

Haegarda is a prescription medication, used to prevent episodes of swelling and pain caused by a certain genetic disease (hereditary angioedema - HAE). Most people with this condition have very little C1-esterase inhibitors. In some cases, people with normal C1-esterase levels are abnormally active.
There are many causes of swelling in the human body. Parts where swelling can occur are the hands, feet, extremities, face, tongue, or throat. Abdominal swelling can cause symptoms such as severe pain, nausea, vomiting, or diarrhea. Haegarda works by increasing the amount of C1-esterase inhibitor in the body to treat sudden attacks of swelling caused by HAE.

2. How to use Haegarda thuốc

If you are using Haegarda at home, learn all the instructions you need to use it properly. If Haegarda and the solution used for reconstitution have been refrigerated, let both come to room temperature before reconstitution. Be careful not to heat the medicine in any other way (such as in the microwave or in hot water). Before use, inspect the product visually for microscopic particles or discoloration. If the drug is not sensory, it should not be used. After completing the preparation of Haegarda, it is necessary to administer subcutaneous injection in the abdomen or another location as directed by the doctor, usually every 3 or 4 days. Before injecting each dose, it is necessary to clean the injection site with alcohol. Change the injection site each time to minimize subcutaneous damage. Do not inject into skin that is itchy, swollen, painful, bruised, or red. Avoid injecting under skin with scars or stretch marks. The dose of Haegarda injection is based on the patient's medical condition, body weight, and response to treatment. Patients need to take the full dose to maximize the effectiveness of the drug. Talk to your doctor if your condition does not improve or gets worse after taking the medicine.

3. Side effects when using Haegarda

When using Haegarda, patients may experience pain/redness/swelling at the injection site, cold-like symptoms (such as watery eyes, sneezing, runny nose, stuffy nose, or dizziness). If any of these side effects persist or get worse, the patient should inform the doctor or pharmacist as soon as possible. Prescribing Haegarda should only be done after your doctor has judged that the benefits to you outweigh the risks from side effects. Most patients using this drug have no serious side effects. Haegarda has the potential to increase the risk of blood clot formation (such as pulmonary embolism, stroke, heart attack, deep vein thrombosis), especially when used in high doses. Therefore, the patient will be at increased risk of blood clots if there is a history of blood clots, heart disease / vascular disease, heart failure, stroke ... before. See your doctor right away if you notice any of the following side effects of Haegarda: Shortness of breath/fast breathing, chest/jaw/left arm pain, unusual sweating, confusion , sudden dizziness/fainting, pain/swelling/heat in the groin, calf, sudden or severe headache, trouble speaking, numbness, weakness on one side of the body, or sudden vision changes. Serious allergic reactions to Haegarda are very rare. However, in the event of a severe allergic reaction, the patient should seek immediate medical attention, such as a rash, itching, or swelling (especially in the face, tongue, and throat). , severe dizziness and difficulty breathing.

4. Caution when taking Haegarda

Before using Haegarda, talk to your doctor or pharmacist about your allergy to the drug. Before taking Haegarda, tell your doctor or pharmacist your medical history, especially of problems related to blood clots (such as blood clots in the lungs, legs). Haegarda has the potential to lead to vertigo. Therefore, patients should not drive, use machines, or perform any work that requires alertness, until you can do so safely. Haegarda is made from donor plasma. Even though it has been carefully tested and has gone through a special manufacturing process, it is still possible to contain viruses and cause drug-related infections (e.g. viral infections such as hepatitis). During pregnancy, pregnant women should only use this medicine when absolutely necessary. Discuss the risks and benefits with your treating physician for information. It is not known whether this medicine passes into breast milk. Consult your doctor before breast-feeding.

5. Interaction between Haegarda and other drugs

Drug interactions may change how Haegarda works or increase the risk of serious side effects. If possible, list all the products you are using to your doctor and pharmacist to avoid potential interactions. Do not take, stop or change the dose of any medicine without your doctor's approval.

6. Some other notes when using Haegarda

6.1. Overdose If you have overdosed on Haegarda and have severe symptoms such as fainting or difficulty breathing, call 911 immediately. To avoid the risk of overdose, do not take Haegarda with other drugs than prescribed by your doctor. Before you travel, talk to your doctor to make sure you get enough medication for the days you're away from home. 6.2. Missed dose Patients should receive each dose of Haegarda exactly as prescribed. If you miss a dose, ask your doctor or pharmacist right away for the next dosing schedule. Do not arbitrarily double the dose to supplement.
6.3. Storage Store unmixed vials in their original containers, refrigerated or at room temperature, away from light or moisture. Do not freeze during storage. After mixing, use this medicine immediately or within 8 hours. Do not refrigerate the reconstituted solution.
Knowing the information about Haegarda drug before using it always brings positive effects as well as reduces risks for patients.

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Reference source: webmd.com