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Granisetron is a drug that works by blocking serotonin that can cause vomiting. The drug is used for cancer patients treated with chemotherapy or those who have vomiting after surgery.
1. What is the effect of Granisetron?
Granisetron is used alone or with other drugs to prevent nausea and vomiting caused by chemotherapy treatment for cancer patients. Another use of Granisetron is to prevent and treat nausea and vomiting in adults after surgery. Granisetron can block serotonin, which causes vomiting, in the body.
2. How to use Granisetron.
How to administer Granisetron is by direct injection into a vein over 30 seconds or it can be mixed in intravenous fluids and injected into a vein over a longer period of about 5 minutes. The time of injection is before cancer chemotherapy or before, during and after surgery
If you are self-administering Granisetron at home you need to learn all instructions for use from your healthcare professional. Before use, inspect the medication visually for particles or discoloration. If you see such phenomena, do not use the drug. Do not mix granisetron with other drugs in the same injection or inject other drugs into the same vein at the same time.
Dosage is based on an individual's medical condition, response to treatment, and body weight. Use this medication exactly as directed to get the most out of it. Follow the prescribed treatment and do not arbitrarily increase the dose or use it more often than prescribed. If your nausea doesn't improve or if it gets worse, tell your healthcare provider for further assistance.
Thuốc Granisetron được tiêm trực tiếp vào tĩnh mạch
3. Side effects of drugs
You may experience headache, diarrhea, dizziness, fever, or pain, redness, and swelling at the injection site while using Granisetron. If you notice any side effects that persist or get worse, tell your doctor for help.
If your doctor has prescribed this medicine for you, he or she has considered that the benefit to you outweighs the risk of side effects. Side effects are also rare, and many people use this medication without serious side effects.
Tell your doctor if you have any serious side effects such as stomach or stomach pain, chest pain, fast heartbeat, irregular heartbeat, severe dizziness and fainting.
Granisetron can increase serotonin and can also cause serotonin toxicity syndrome but it happens very rarely. However, this risk is increased if you are also taking other medications that also increase serotonin.
You can have an allergic reaction, but it happens very rarely. However, get medical help right away if you notice any symptoms of a serious allergic reaction such as rash, itching, swelling, and difficulty breathing.
4. Notes when using drugs
Before using granisetron, tell your doctor if you are allergic to it or you are allergic to other anti-nausea serotonin blockers such as dolasetron, ondansetron, or if you have any other allergies. This product may contain inactive ingredients that may cause allergic reactions or other problems. When you intend to use Granisetron, tell your doctor about your medical history, especially stomach and intestinal problems.
This medicine can make you dizzy so you should not drink alcohol or use marijuana while taking it as it can make you more dizzy. Do not drive, use machines, or do anything that requires alertness after taking this medicine.
Granisetron medicine may affect heart rhythm by causing tachycardia, severe irregular heartbeat and other symptoms such as severe dizziness, fainting.
Before using granisetron, tell your doctor if you have any medical conditions such as heart problems such as heart failure, slow heartbeat, family history of certain heart problems. Low levels of potassium or magnesium in the blood can also increase the long-term risk of medications affecting the heart.
Age can make you more sensitive to the side effects of medications. During pregnancy, this medicine should be used only when clearly needed and consult your doctor before taking if you are breast-feeding.
Thuốc Granisetron có thể gây ra tác dụng phụ khiến nhịp tim nhanh
5. Drug interactions.
Drug interactions can increase the risk of serious side effects and reduce the positive effects of medications. To avoid drug interactions while taking Granisetron, keep a list of all your products, including prescription, over-the-counter, and herbal products, and share it with your doctor. Do not start or stop taking or change the dose of any medicine without your doctor's approval.
The risk of serotonin toxicity is also increased if you are also taking other drugs that increase serotonin such as ecstasy, some antidepressants.
Let your doctor know if you miss your dose or do not take it at the exact time before your scheduled chemotherapy or surgery as treatment or surgery may need to be scheduled again.
When disposing of medication do not flush it down the toilet or down the drain unless instructed to do so. Dispose of this product appropriately when it has expired or is no longer needed.
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Reference source: webmd.com
