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Gastrylstad is prescribed by doctors to relieve discomfort in disorders such as indigestion, gastroesophageal reflux disease. So is Gastrylstad an antibiotic, and what is the dose? What are the uses and side effects when using it? Let's find out information about the drug Gastrylstad in the following article.
1. Is Gastylstad an antibiotic?
Gastylstad has the main ingredient is Simethicone belonging to the group of digestive drugs, packaged in the form of a 15ml oral emulsion. Manufactured by a pharmaceutical company.
Mechanism of action:
Active ingredient Simethicone is a viscous, gray, translucent liquid containing 4 to 7% (kl/kl) Silicon dioxide. Simethicone's mechanism of action is to reduce the surface tension of gas bubbles in the stomach, causing them to clump together. Therefore, Simethicone is used to remove gas, vapor or foam in the gastrointestinal tract before gastrointestinal X-ray, and has the effect of relieving abdominal distension and indigestion. The drug is excreted unchanged in the faeces. Pharmacokinetics:
Physiologically Simethicone is an inert substance, so it is not absorbed from the gastrointestinal tract, hindering the secretion of gastric juice or the absorption of nutrients into the body. Toxicity:
As recommended, the active ingredient Simethicone should not be used to treat colic in infants and young children because there is not much information on the safety of the drug. According to clinical reports, due to the non-absorbable nature of simethicone, no clinically significant side effects or toxicity were observed. For the same reason, simethicone is often prescribed by doctors in combination with antacid preparations.
2. Gastrylstad uses, dosage and side effects
Indications of the drug Gastylstad:
Gastylstad is used as an adjunct to the treatment of many diseases, including post-operative gas obstruction, gas swallowing, functional dyspepsia, gastric ulcer, colon spasm or irritation; Postoperative flatulence and discharge; Support treatment of symptoms of flatulence, functional abdominal distension and gas pain after surgery; Used before gastroscopy to enhance imaging and before bowel radiographs to reduce air bubbles. The usual adult dose is 160-400 mg/day in divided doses, taken after each meal and at bedtime. Simethicone is also used in combination with antacids, antispasmodics, sedatives, and digestive agents.
Contraindications of the drug Gastrylstad:
Do not use the drug for patients who are allergic to any of the components of the drug Gastylstad; Self-administering Gastrylstad as an anti-flatulence medication to relieve symptoms of bloating (eg, flatulence, feeling of gas, bloating); Not recommended for the treatment of colic in infants; Abdominal pain right after eating; Enteritis. Precautions when using Gastylstad:
Do not use when the drug changes color or has a strange smell, when the emulsion is separated into 2 layers. Gastylstad contains sorbitol, which may affect the bioavailability of other medicinal products when taken concomitantly. Caution should be exercised for additive effects when taking drugs or diets containing sorbitol (fructose).
3. Gastylstad side effects
Although it may be rare, some people may experience very serious side effects when using the drug. Therefore, tell your doctor or seek medical attention if you have any of the following signs or symptoms:
Rash, hives, itching; Red, swollen, blistering, or peeling skin with or without fever; Wheezing, tightness in the chest or throat; Difficulty breathing, swallowing, or talking; Unusual hoarseness; Swelling of the mouth, face, lips, tongue, or throat. 4. Gastylstad Drug Interactions Concomitant use of Gastylstad or antacid preparations may decrease the oral bioavailability of Thyroid Hormone. The pharmacological effects of thyroid hormone may be reduced. The exact mechanism of interaction is unknown but may involve nonspecific adsorption of Thyroid Hormone to multivalent cations, resulting in an insoluble complex that is poorly absorbed from the gastrointestinal tract. In addition, because stomach acid is required for adequate absorption of Thyroid Hormone, agents that affect pH in the stomach can decrease thyroid hormone absorption. There have been case reports showing decreased effectiveness of Thyroid Hormone when taken with antacids containing aluminum and magnesium, as well as other products containing polyvalent cations such as calcium and iron.
In one report, a healthy man with levothyroxine 150mcg/day had significantly increased serum thyrotropin (thyroid-stimulating hormone, or TSH) levels while taking aluminum and magnesium hydroxide antacids. Obvious interactions were also observed on the next 2 refinements. Other case reports have described an increase in levothyroxine dosing requirements during antacid use.
5. How to use Gastrylstad effectively How to use Gastylstad:
Use Gastrylstad suspension as prescribed by your doctor. Read all the information provided to you. Follow all instructions closely; Take Gastrylstad suspension after meals and at bedtime or as directed by your doctor; Measure the liquid dosage carefully. Use the measuring device supplied with the Gastylstad suspension; This medication may be given directly into the oral cavity toward the cheek or mixed with formula, water, or other liquid. Shake before using. Dosage of Gastylstad:
Adults and children over 12 years old: 0.6 ml - 1.8 ml x 4 times / day, the total dose should not exceed 7.5 ml / day; Children 2 - 12 years old: 0.6 ml x 4 times/day (maximum dose in self-treatment is 3.6 ml/day); Children under 2 years: 0.3 ml x 4 times / day (maximum dose in self-treatment is 1.8 ml / day). Note: The above dosage is for reference only. The specific dose depends on the condition and the progression of the disease. To get the right dose, you need to consult your doctor or healthcare professional.
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