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Posted by Resident Doctor, Doctor Nguyen Thi Thuy Hang - Doctor of Microbiology - Laboratory Department - Vinmec Times City International Hospital
Filmarray system is a system based on real-time PCR technique, so it has similar sensitivity and specificity. However, in terms of total capacity, the FilmArray system is not as good as conventional PCR because it can only process one sample at a time.
Currently, under the development of science and technology, technological applications for laboratory diagnostic methods are also increasingly being developed. Many laboratories are using PCR (polymerase chain reaction) test technique, which is a technique with high sensitivity and specificity, helping to quickly diagnose pathogens (within 4-8 hours). However, the application of this technique requires many stages and depends a lot on human skill factors such as extraction, mixing, machine operation...
In the past few years, the company developed the FilmArray PCR system. This is a system that works on the principle of real-time PCR, so the sensitivity and specificity are equivalent to this PCR test technique.
The use of this system has many advantages over real time PCR:
First, it is a fully integrated closed-loop system that minimizes contamination concerns while providing the ability to full automation from sample extraction to results; Second, shortening the time to return results, the system works quickly and accurately with each patient sample, instead of the results being available after 4-8 hours like conventional PCR methods, with the FilmArray system, the results are available. after just over 1 hour from entering patient samples into the machine; Third, thanks to the integration of microorganisms into one panel, the FilmArray system can simultaneously diagnose multiple microorganisms (including bacteria, viruses, fungi and parasites) after more than 1 hour. Depending on the panel design, the number of microorganisms is different (can detect from 14-34 pathogens), but compared to the conventional multi-primer PCR test method, the number of microorganisms in a panel of the system FilmArray system is usually 3-4 times more. Therefore, instead of running 3-4 times of single panels with real-time PCR, we only need to run it once with this system.
Hệ thống Filmarray được ứng dụng các công nghệ hiện đại
Although the running time of an individual patient sample is very fast, in terms of total capacity, the FilmArray system is not as good as conventional PCR because it can only process one sample at a time. time. To overcome this drawback, it is necessary to add running modules depending on the needs of the laboratory.
In summary, although the overall capacity is not high, the FilmArray system is an advanced system that enables fast, accurate, simultaneous diagnosis of many types of microorganisms. Currently, Vinmec Times City International Hospital has deployed the FilmArray system with a number of panels within 60 that can simultaneously detect many bacterial pathogens, viruses, fungi, and drug-resistant bacteria such as the 37-germ detection panel. lower respiratory tract infections; panel detects 14 pathogens causing meningitis , panel detects 22 pathogens causing gastrointestinal inflammation...
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