Detrol: Uses, indications and notes when using

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Detrol is an antispasmodic drug used to treat overactive bladder. By relaxing the muscles in your bladder, Detrol improves your control of urination. It helps to reduce urine leakage, the feeling of needing to urinate right away, and frequent urination.

1. Indications and contraindications of Detrol

Detrol is indicated in the following cases:
Overactive bladder The condition in which you want to urinate leads to urine leakage. Increased need to urinate often Urgent or sudden urge to urinate Detrol is contraindicated in the following cases:
Dementia Myasthenia gravis, musculoskeletal disorders Angle-closure glaucoma Torsion glaucoma peak, a type of irregular heartbeat QT interval prolongation on ECG Abnormal ECG with QT changes at birth Narrowing of the opening between the stomach and small intestine Severe liver disease Severe kidney failure Bladder obstruction Incontinence Stomach emptying problems Poor metabolizer CYP2D6 2. How to take Detrol Read the leaflet from your doctor before you start using Detrol and each time you get a refill. If you have any questions about how to use Detrol, ask your doctor. Take Detrol by mouth on an empty stomach or on an empty stomach, as directed by your doctor, usually twice a day. Use Detrol regularly to get the most benefit from it. To help you remember and avoid forgetting to take a pill, take Detrol at the same times each day. The dose of Detrol is calculated based on your medical condition especially kidney and liver disease, response to treatment and other medicines you are taking. Be sure to tell your doctor about all the medicines you use including prescription drugs, over-the-counter medicines, and herbal products. Do not increase your dose or take Detrol more often than directed. Doing so will not help your condition improve faster, but it will also increase your risk of potentially serious side effects. Tell your doctor if your condition persists or worsens after using Detrol.

3. Side effects of Detrol While using Detrol, you may experience dry mouth, dry eyes, headache, constipation, stomach pain, dizziness, drowsiness, fatigue or blurred vision. If any of these effects persist or get worse, tell your doctor right away.
To relieve dry mouth while taking Detrol, suck on hard candy (sugar-free) or shaved ice, chew gum (sugar-free), drink water, or use a saliva substitute.
To prevent constipation, eat plenty of fiber, drink enough water and exercise, laxatives may also be necessary.
Remember that your doctor has prescribed Detrol because they have judged that its benefits outweigh the risk of side effects. Many people use Detrol without any serious side effects.
Tell your doctor right away if you have any serious effects of Detrol, including: Change in vision, heaviness or pain in the abdomen, difficulty urinating, signs of a kidney infection such as painful urination, pain back, fever.
Get medical help right away if you have any very serious side effects of Detrol medicine, including: Fast/slow/irregular heartbeat, severe dizziness, fainting.
A very serious allergic reaction to Detrol is very rare. However, if you notice any symptoms of a serious allergic reaction to Detrol, including: Rash, itching or swelling especially of the face/tongue/throat, severe dizziness, shortness of breath.
Here are the Detrol side effects by likelihood:
Common Detrol side effects include:
Urinary tract infections Dry mouth Constipation Headache Less common Detrol side effects include :
Change in vision Dry eyes Inflammation of the lining of the sinuses Indigestion Dry skin Drowsiness Dizziness Low energy Flu-like symptoms Weight gain Difficult or painful urination Incontinence Stomach cramps Anxiety Effects Effects Rare side effects of Detrol include:
QT interval prolongation on ECG Heart pounding Heart palpitations Anaphylactic shock Angioedema Heart palpitations Confusion Amnesia Dehydration Diarrhea This is not a complete list of side effects. possible side effects of Detrol. If you notice other effects of Detrol not listed above, contact your doctor.

4. Precautions for Detrol Side Effects Before taking Detrol, tell your doctor if you are allergic to it; or fesoterodine and any other allergies. Detrol medicinal products may contain inactive ingredients that can cause allergic reactions or other problems.
Before using Detrol, tell your doctor your medical history, especially of:
Bladder emptying problems such as urinary retention, bladder outlet obstruction. Severe stomach/intestinal obstruction (water retention). Glaucoma Stomach/intestinal diseases such as ulcerative colitis, slow movement of the stomach/intestines. Severe constipation Kidney disease Liver disease Myasthenia gravis Detrol may cause a condition that affects the heart rate (QT prolongation). QT prolongation can rarely cause a severe (rarely fatal) fast or irregular heartbeat and other symptoms such as fainting and severe dizziness that require immediate medical attention.
The risk of QT prolongation with Detrol may be increased if you have certain medical conditions or are taking other medicines that can prolong QT. Before using Detrol, tell your doctor both the medicines you are taking and if you have any of the following conditions: Certain heart problems (heart failure, slow heartbeat, QT prolongation in ECG), money family history of certain heart problems (electrocardiogram QT prolongation, sudden cardiac death).
Low blood levels of magnesium or potassium may also increase the risk of QT prolongation on the electrocardiogram. This risk may be increased if you use certain types of diuretics or if you have conditions such as excessive sweating, diarrhea, or vomiting.
Older adults may be more sensitive to the side effects of Detrol, especially QT prolongation, drowsiness, confusion, constipation or difficulty urinating. Drowsiness and confusion can increase the risk of falls.
Detrol can make you dizzy, drowsy, or blur your vision, and alcohol and marijuana can make you more dizzy or drowsy. Do not drive, use machines, or do anything that requires alertness or clear vision while using Detrol, until you can do so safely. Limit alcohol and absolutely do not use marijuana while being treated with Detrol.
Detrol can make you sweat less, making you more susceptible to heat stroke. Avoid doing activities that can make you too hot, like working out or exercising in hot weather, or using a hot tub. In hot weather, drink plenty of water and wear loose clothing. If you feel overheated, quickly find a way to cool down and rest. Get medical help right away if you have a fever that doesn't go away, mental or mood changes, headache, or dizziness.
Women during pregnancy, Detrol should only be used when absolutely necessary. Discuss the risks and benefits of the drug with your doctor. That is, we do not know if Detrol passes into breast milk. Therefore, women who are breastfeeding should consult their doctor when using Detrol.
5. Detrol Drug Interactions Drug interactions can change the way Detrol works or increase your risk of serious side effects. Make a list of all the medications you take including prescription/nonprescription drugs and herbal products and share it with your doctor. Do not start, stop, or change the dose of any medicine while you are using Detrol, without your doctor's approval. Some drugs that may interact with Detrol include: Anticholinergics (such as atropine, scopolamine), other antispasmodics (such as dicyclomine, propantheline), certain anti-Parkinsonian drugs (such as trihexyphenidyl), belladonna alkaloids, potassium tablets/capsules, pramlintide. Many drugs besides Detrol have may affect heart rhythm (QT prolongation), including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics such as erythromycin. Tell your doctor if you are taking other products that cause drowsiness including alcohol. , marijuana, antihistamines (such as cetirizine, diphenhydramine), sleeping or anti-anxiety medications (such as alprazolam, diazepam, zolpidem), muscle relaxants, and opioid pain relievers (such as codeine).

6. What to do when overdose or forget to use Detrol? If you or someone else has overdosed on Detrol and has serious symptoms such as fainting or difficulty breathing, call 911. Symptoms of a Detrol overdose may include a fast/slow/fast heartbeat/ irregularity, fainting, unusual excitement, mental/mood changes.
If you miss a dose of Detrol, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Use your next dose of Detrol at the usual time and do not take a double dose.
7. How to Store Detrol Store Detrol at room temperature, away from light and moisture. Do not store Detrol in the bathroom keep it away from children and pets.
Do not flush Detrol down the toilet or down the drain unless instructed to do so. Dispose of this medication appropriately when it has expired or is no longer needed.

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Reference source: webmd.com