Aubagio drug: Uses, indications and precautions when using

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Aubagio is used in the treatment of multiple sclerosis (MS), which is thought to reduce certain immune system cells (lymphocytes) that can attack nerves in the body. brain and spinal cord. This helps reduce the number of flares of the disease and slows down the physical problems caused by multiple sclerosis.

1. What is Aubagio? Aubagio is used in the treatment of multiple sclerosis (MS), which is thought to work by reducing certain immune system cells (lymphocytes) that can attack nerves in the brain. and spinal cord. This helps reduce the number of flares (relapses) of the disease and helps slow down the physical problems caused by multiple sclerosis.
2. Indications of the drug Aubagio Aubagio drug is indicated in the following cases:
Relapsing episodes of multiple sclerosis Secondary progressive multiple sclerosis Besides, when taking multiple sclerosis drugs, patients should note , carefully read the instructions for use of the drug provided by your doctor before starting to take it. Take Aubagio on an empty stomach or on a full stomach as directed by your doctor, usually once a day. The dose is calculated by your doctor based on your medical condition and response to treatment. Take Aubagio regularly to get the most benefit.
To help remember and avoid forgetting to take a pill, take Aubagio at the same time each day. After you stop treatment with Aubagio, your doctor may prescribe another medicine (cholestyramine or activated charcoal powder) to help speed up the removal of teriflunomide (the main ingredient in Aubagio) from your body. This medicine may be used if you have serious side effects, or if you are a woman of childbearing age, or a man planning to father a child. Otherwise, teriflunomide can stay in your body for up to 2 years after stopping treatment.
Tell your doctor if your multiple sclerosis symptoms do not improve or if they worsen while using Aubagio. Tests such as TB skin test, kidney function, liver function, complete blood count, blood pressure, blood potassium level should be done before you start treatment and periodically rechecked to make sure Monitor progress or check for side effects. If you are prescribed another medicine to help speed up the elimination of teriflunomide after you stop treatment with Aubagio, your doctor may also do tests to check your blood levels of teriflunomide.
3 . Side effects of the drug Aubagio During the use of Aubagio medicine, symptoms such as diarrhea, nausea or a feeling of tingling, burning, numbness or stinging may appear on the skin. If any of these symptoms persist or worsen during use, tell your doctor immediately.
You may experience temporary hair loss while using Aubagio. However, the hair will grow back normally after the treatment with Aubagio is finished. Remember that your doctor has prescribed Aubagio because he or she has judged that the benefit to you outweighs the risk of side effects. Many people use Aubagio and don't have any serious side effects.
Tell your doctor if you have any serious side effects while using Aubagio, including:
Easy bruising or bleeding. New onset of dyspnea, or worsening of previous shortness of breath. Numbness or tingling in the hands or feet is new or has been and is now getting worse. Side pain Symptoms of high blood potassium levels such as muscle weakness, slow or irregular heartbeat. Unusual fatigue.

Aubagio may increase blood pressure, so check your blood pressure often and let your doctor know if the results are higher than normal.
Aubagio may decrease your ability to fight infections, which could make you more likely to get serious (rarely fatal) infections or make any infections you develop more likely. heavier. Get medical help right away if you have any signs of infection such as a sore throat that doesn't go away, fever, chills, cough, swollen lymph nodes.
Serious allergic reactions to Aubagio are very rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction while using Aubagio, including: rash, itching, or swelling anywhere on body, especially in the face, tongue, or throat, severe dizziness, trouble breathing.
Aubagio side effects by likelihood:
High level of Alanine transaminase Low blood phosphate level Flu, Common cold, Skin prickling, Peripheral neuropathy, Infections, Diarrhea, Hair loss, Headaches Nausea Upper abdominal pain Uncommon side effects of Aubagio include:
Abnormal liver function Acute kidney failure Thrombocytopenia in the blood High levels of potassium in the blood Low levels of neutrophils Levels of white blood cells Low Herpes Simplex infection of the skin, mouth, or genitals Toothache Stomach bloating Blurred vision Carpal tunnel syndrome Heart pounding or pounding High blood pressure Itching Muscle pain Weight loss Rare side effects of Aubagio include: Includes:
Anaphylaxis Stevens-Johnson syndrome is a skin disorder with blistering and peeling of the skin. Toxic epidermolysis bullosa is a type of skin disorder. Angioedema Leukopenia Interstitial pneumonia DRESS syndrome is a type of severe allergic skin reaction. Honeycomb Eosinophilia in the blood Hepatitis Kidney stones Liver failure Lung tissue problems Opportunistic fungal infections Pancreatitis Fungal pneumonia called Pneumocystis Jiroveci Psoriasis Swollen lymph nodes Very low levels of granulocytes Phat how are you?

This is not a complete list of possible Aubagio side effects. If you notice other effects of Aubagio medicine not listed above, contact your doctor for full advice.
5. Precautions for Aubagio Side Effects Before taking Aubagio, tell your doctor if you are allergic to it or to leflunomide. Aubagio may contain inactive ingredients that can cause allergic reactions or other problems.
Before using Aubagio, tell your doctor your medical history, especially of:
Bone marrow or blood disorders Immune system disorders such as cancer, HIV infection. Current or recent infection such as tuberculosis. High blood pressure Liver problems Lung disease . Do not get vaccinated without your doctor's consent while using Aubagio. Avoid contact with people who have recently received a live vaccine such as the nasal flu vaccine.
Before surgery, tell your doctor or dentist that you are taking Aubagio and all the products you use including prescription drugs, over-the-counter medicines and herbal products.
Teriflunomide can pass into the semen of men treated with Aubagio and it is not known how it affects sperm. Men should use reliable birth control such as condoms during treatment with Aubagio.
After stopping Aubagio, men who want to have children should take another medicine prescribed by their doctor to speed up the removal of teriflunomide from the body. Aubagio should not be used during pregnancy, as it may harm the unborn baby. Before starting Aubagio, women of childbearing age must have a negative pregnancy test. Discuss the use of reliable forms of birth control such as birth control pills, intrauterine device - IUD with your doctor during treatment with Aubagio. If you become pregnant or think you may be pregnant while using Aubagio, tell your doctor right away. Aubagio may pass into breast milk and may have undesirable effects on the infant. Therefore, doctors do not recommend breastfeeding while using Aubagio. Consult your doctor before breast-feeding while you are being treated with Aubagio.
6. Aubagio Drug Interactions Drug interactions can change the way Aubagio works or increase your risk of serious side effects. You need to make a list of all the products you use including prescription/over-the-counter drugs and herbal products and share that list with your doctor. Because leflunomide used to treat rheumatoid arthritis is very similar to the drug Aubagio, do not take it while you are taking Aubagio.
7. What to do when overdose and forget Aubagio pills? If you or someone else has overdosed on Aubagio and has severe symptoms such as fainting or difficulty breathing, call 911 or take the patient to the nearest hospital.
If you miss a dose of Aubagio, take it as soon as you remember. If you remember it is almost time for your next dose of Aubagio, skip the missed dose and continue taking your next dose as usual. Do not use a double dose of Aubagio to make up for a missed dose.

8. How to store Aubagio drugs Store Aubagio pills at room temperature, away from light and moisture. Do not store Aubagio pills in the bathroom. Keep Aubagio and all medications away from children and pets.
Do not flush Aubagio down the toilet or down the drain unless instructed to do so. Dispose of Aubagio medicine properly when it has expired or is no longer needed by you.
Currently MS cannot be completely cured, drug therapy and some medical interventions will help control symptoms and slow down the progression of the disease better.
Currently, Vinmec International General Hospital has used autologous hematopoietic stem cell infusion with the aim of alleviating autoimmune reactions and long-term recurrence of patients with multiple sclerosis. Up to now, the Hematology and Cell Therapy Unit at Vinmec Hospital has applied treatment to many cases and received positive reviews and the best improvement in patients' health.
The examination and treatment at the hospital is always done by a team of doctors and experts with many years of experience, well-trained in domestic and foreign environments. Therefore, patients can rest assured when choosing Vinmec hospital.

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Reference source: webmd.com