Are beta HCG levels different when you're pregnant with twins?

This is an automatically translated article.

The article was professionally consulted by Specialist Doctor I Nguyen Thi Man - Department of Obstetrics and Gynecology - Vinmec Danang International General Hospital. The doctor has more than 10 years of experience in diagnosing, consulting and treating in the field of Obstetrics and Gynecology.
HCG is a hormone produced during pregnancy, hCG hormone has many important roles in the development of the fetus. In addition, because hCG levels increase rapidly after conception, hCG testing helps in early diagnosis and monitoring of pregnancy status.

1. What is hCG hormone?

hCG stands for Human chorionic Gonadotropin, which is a hormone of sialoglycoprotein nature, with a molecular weight of about 46,000 daltons. hCG consists of two subunits, alpha and beta, in which only the beta subunit is specific for hCG hormone because the alpha subunit has the same amino acid sequence as many other hormones in the body.
hCG is made up of placental cells, has an important role in helping to nourish the mature embryo, stimulating the production of the hormones oestrogen and progesterol to help thicken the uterine lining to supply blood for development. It also sends a signal to the brain to temporarily stop the menstrual cycle. In addition, monitoring hCG levels helps in early detection of pregnancy and helps to monitor the condition periodically.

HCG được tạo thành từ các tế bào nhau thai giúp nuôi dưỡng phôi thai trưởng thành
HCG được tạo thành từ các tế bào nhau thai giúp nuôi dưỡng phôi thai trưởng thành

2. Changes of hCG levels during pregnancy

In healthy, non-pregnant women, hCG levels are usually less than 5mUI/ml. In pregnant women, hCG levels will be higher than 25mUI/ml. If the hCG level is in the range of 6-24mUI/ml, pregnancy has not yet been determined and needs further testing and monitoring. After delivery or miscarriage, after 4-6 weeks hCG levels will return to normal <5mUI/ml.

Trắc nghiệm: Sự thay đổi nồng độ beta HCG thay đổi theo tuổi thai

hCG là một hormon quan trọng được tiết ra khi phụ nữ mang thai. Nồng độ beta hCG được tính theo đơn vị mUI/ml. Hãy cùng theo dõi bài trắc nghiệm sau đây để biết được Nồng độ beta HCG thay đổi theo tuổi thai như thế nào?

hCG is produced very early, right after the egg is fertilized into an embryo that attaches to the lining of a woman's uterus. When a new baby is born, the level of hCG in the blood is quite low, but they increase very quickly, usually doubling every 48-72 hours. hCG levels will peak between weeks 8 and 11 of pregnancy, then gradually decrease and level off for the rest of the pregnancy. The hCG level of a woman's body will change with gestational age as follows:
3 tuần 5-50 mUI/ml 9-12 tuần 25700-288000 mUI/ml
4 tuần 5-426 mUI/ml 13-16 tuần 13300-254000 mUI/ml
5 tuần 18-7340 mUI/ml 17-24 tuần 4060-165400 mUI/ml
6 tuần 1080- 56.500 mUI/ml Từ tuần 25 đến ngày sinh 3.640-117.000 mUI/ml
7-8 tuần 7650-229000 mUI/ml 4-6 tuần sau sinh <5mUI/ml
hCG levels vary greatly between pregnant women and in each woman, the variability of hCG levels at different times during pregnancy is also very large, it is important to note that the results hCG is in the common average range and is the increase and decrease in hCG levels consistent with each stage of pregnancy.
When hCG levels are too high or too low for the normal physiological curve, abnormalities in pregnancy may have occurred. If hCG levels are too low, there is a chance of miscarriage, stillbirth, or an ectopic pregnancy. If the hCG level is too high, it may be a phenomenon of placental disease, ovulatory, trophoblastic disease, multiple pregnancy,...

3. Is the beta hCG index of a twin pregnancy different from that of a normal singleton?

Women carrying twins often have higher hCG levels than singleton pregnancies, and the beta hCG test results for twins are often 30-50% higher than normal pregnancies. However, this difference is not apparent until later in pregnancy.
The difference in hCG levels between pregnant women with each other and in the same woman pregnant at different times is very different. There is no specific number for hCG levels at one point in time, but rather a range of numbers. Therefore, the results of beta hCG should not be used to diagnose a twin pregnancy because the accuracy is not high.

Phụ nữ mang song thai thường có nồng độ hCG cao hơn so với người mang thai đơn
Phụ nữ mang song thai thường có nồng độ hCG cao hơn so với người mang thai đơn
Not all women who are pregnant with twins have elevated hCG levels, and there are also women who, despite their very high hCG levels, actually give birth to only one baby. Doctors can only accurately diagnose twin pregnancy or not after conducting an ultrasound, the ultrasound technique also helps to accurately assess the gestational age and level of fetal development.
If the doctor does not appoint a regular hCG level test to monitor and treat some diseases during pregnancy, pregnant women do not need to test hCG levels many times. Pregnancy monitoring can rely on many other means of greater stability and accuracy.
Vinmec International General Hospital is one of the hospitals that not only ensures professional quality with a team of leading medical doctors, modern equipment and technology, but also stands out for its examination and consultation services. comprehensive and professional medical consultation and treatment; civilized, polite, safe and sterile medical examination and treatment space. Customers when choosing to perform tests here can be completely assured of the accuracy of test results.

Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.

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