Answer: Is basedow's disease cancer?

This is an automatically translated article.

Graves' disease is an autoimmune disorder caused by stimulation of thyroid hormone (TSH) receptors on thyroid follicular cells. Basedow's disease is not cancer, but depending on the form of the disease, complications of thyroid cancer and breast cancer can appear.

1. What kind of disease is cancer?

Cells are the basic units that make up the human body. Cells grow and divide to make new cells when the body needs them (usually cells run out when they are too old or damaged and they are replaced with new cells). Cancer begins when genetic changes interfere with this orderly process. Cells begin to grow uncontrollably. These cells can form a mass (tumour). A tumor can be benign (it can grow but not spread) or malignant (it can grow and spread to other parts of the body).
The main types of cancer include:
Carcinoma: Carcinoma that starts in the skin or tissue that covers the surface of internal organs and glands. It often forms solid tumors such as prostate cancer, breast cancer, lung cancer... Connective tissue cancer: The disease begins in the tissues that support and connect the body. It usually develops in fat, muscle, nerves, tendons, joints, blood vessels, lymph vessels, cartilage, or bone. Leukemia (blood cancer): A disease that begins when healthy blood cells change and grow out of control. Lymphoma: Lymphoma is cancer that begins in the lymphatic system, which is the network of blood vessels and the thyroid gland that fights infection. Metastasis is when a cancerous tumor grows, the blood and lymph systems can carry cancer cells to other parts of the body and grow into new tumors.

2. What is basedow's disease?

Graves' disease, also known as Graves' disease, is an immune system disorder that leads to overproduction of thyroid hormone. Basedow's disease is one of the most common forms of hyperthyroidism.
Symptoms of basedow's disease include: weight loss despite increased appetite, fast heart rate, high blood pressure, profuse sweating, increased sensitivity to heat, bowel movements, weak muscles or tremors, lumps neck development, bulging eyes, dark skin, change in menstrual cycle in women, ...
In case the patient has signs such as fever, agitation, delirium, and rapid pulse, emergency care is needed. timely. It is possible that the patient has a complication with thyrotoxic that affects the thyroid hormone, which is life-threatening.

3. Is basedow's disease cancer?

Several studies have examined the possible association of basedow's disease with subsequent cancers. These cancers are caused by the immunity of basedow's disease. Cancer can occur as a result of tolerance by an abnormal host immune system. Other studies have also shown a higher incidence of subsequent cancer in people with basedow's disease than in those with autoimmune thyroid disease. At the same time, being hyperthyroid will not protect a patient from thyroid cancer.
The increased risk of thyroid cancer in people with Graves' disease was observed in a Swiss cohort study showing that thyroid hormone affects both normal breast cell differentiation and cancer cell proliferation breast as well as stimulate the disease formation of some other types of cancer.
May explain more about the increased risk of thyroid cancer in people with basedow's disease. Graves' hyperthyroidism is caused by thyroid-stimulating antibodies (TSAb), which bind to and activate thyrotropin receptors on thyroid cells. Thyroid-stimulating antibody (TSAb) may play a role in determining the aggressiveness of thyroid cancer in patients with basedow. In addition, thyroid carcinoma can also be associated with other types of hyperthyroidism.
Breast cancer is the most common disease in women. Thyroid follicular cells and mammary cells accumulate iodine by basal membrane indirect transport by the sodium iodide regulator (NIS) and iodine oxidation in mammary follicular cells, similar to thyroperoxidase of the thyroid gland. Several studies have also demonstrated an increased incidence of breast cancer from patients with autoimmune thyroid disease.
Thyroid-mammary gland cross-relation mainly involves the triiodothyronine (T3) and thyroxine (T4) pathways as well as the activation of thyroid hormone receptors of the mammary gland inducing differentiation and growth-like growth. like estrogen. High levels of T3, T4 are significantly associated with a high risk of breast cancer. However, this mechanism still needs further elucidation.
These results show that people with basedow's disease have a higher risk of thyroid cancer and breast cancer.
Although basedow's disease is not cancerous, some forms of the disease can increase the risk of breast cancer and thyroid cancer. Therefore, for subjects with thyroid diseases, especially basedow's disease, it is recommended to perform thyroid disease tests, periodically visit, and perform thyroid cancer screening and breast cancer screening. Because if these two cancers are detected early, the chances of cure are very high.

Vinmec International General Hospital is a hospital specializing in the diagnosis and treatment of thyroid diseases. It has all the necessary medical equipment to perform simple to complex treatments such as medical treatment, intensive treatment, examination, diagnosis and testing of diseases. Thyroid.
Accordingly, the examination and treatment of thyroid diseases at Vinmec are performed by a team of highly qualified medical professionals who have undergone training and are granted technical certificates. handle quickly and effectively, especially in cases of urgent emergency. Therefore, patients with thyroid diseases can rest assured with a strict, methodical and effective treatment process at Vinmec.
For detailed advice on diagnosis and treatment of thyroid diseases as well as effective treatment methods at Vinmec, please go directly to Vinmec health system nationwide or register. Check online HERE.
References: cancer.net, ncbi.nlm.nih.gov, thyroid.org, webmd.com