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The group of non-steroidal anti-inflammatory drugs is widely used with many different dosage forms and routes of administration, of which the least mentioned are topical products such as Kefentech. So what is Kefentech and how does it work?
1. What is Kefentech?
Kefentech adhesive is a product of JEIL HEALTH SCIENCE INC Company, distributed in Vietnam through Cat Thanh Pharmaceutical Trading Company. The main active ingredient in Kefentech ointment is Ketoprofen (in the group of non-steroidal anti-inflammatory drugs).
Kefentech is used for the symptomatic treatment of conditions such as deforming arthritis, rheumatoid arthritis, periarthritis of the arm-shoulder joint (with symptoms such as pain, stiffness, and numbness of the shoulder), capsulitis. tendon or tendonitis and relieve muscle pain. In addition, Kefentech is also used to treat swelling and pain caused by trauma. Kefentech is prepared in the form of a topical paste, then the active ingredient Ketoprofen will be absorbed directly through the skin to reach the damaged musculoskeletal area and bring about pain relief, while limiting unwanted effects. desirable when systemic administration of Ketoprofen or other NSAIDs.
Each Kefentech patch measures 10x7cm and contains 30mg of Ketoprofen.
2. What is the effect of Kefentech adhesive?
The main active ingredient in Kefentech paste is Ketoprofen, which is essentially a non-steroidal anti-inflammatory drug. Chemically, Ketoprofen belongs to the propionic group and is a derivative of Aryl Carboxylic Acid. Like other non-steroidal anti-inflammatory drugs, Ketoprofen has main effects including anti-inflammatory, analgesic and antipyretic. Ketoprofen's anti-inflammatory mechanism is due to inhibition of the synthesis of proinflammatory substances, including Prostaglandins and Leukotrienes. The active ingredient Ketoprofen in Kefentech paste has analgesic effect from mild to moderate, the site of action is the peripheral pain receptors. Ketoprofen works well for all types of inflammatory pain. The analgesic mechanism of Ketoprofen is inhibition of prostaglandin F2 synthesis, reducing the pain sensitivity of sensory nerves to substances that cause inflammatory reactions such as Bradykinin, Serotonin...
When used topically in the form of a high Kefentech paste, Ketoprofen is absorbed very slowly and causes little accumulation in the body. The relative bioavailability between the topical and oral forms of Ketoprofen is only about 5%. Due to its low bioavailability, it allows Kefentech to be effective locally without systemic effects.
3. Indications, contraindications of Kefentech paste
Kefentech paste is indicated for use with the purpose of reducing symptoms in the following cases:
Deforming arthritis or rheumatoid arthritis; Reducing pain, stiffness, and numbness of the shoulder in patients with periarthritis of the humerus-shoulder joint; Tendonitis and tendinitis; Relieve muscle pain due to causes; Reduce swelling, joint pain caused by injury. Like any other preparation, Kefentech paste is also contraindicated in the following cases:
Patients with a history or local allergy to the active ingredient Ketoprofen or other non-steroidal anti-inflammatory drugs; People with a history of asthma attacks or signs of allergy when using Aspirin or other NSAIDs.
4. Instructions for using Kefentech paste
Patients with appropriate indications for use should stick Kefentech high products on the affected areas. The recommended dosage is 1 patch of Kefentech each time and 2 times per day.
5. Kefentech side effects
When using Kefentech paste, patients are still at risk of unwanted effects, but the rates are relatively rare, specifically as follows:
Allergic or anaphylactoid reactions with symptoms symptoms such as urticaria, dyspnea, facial edema; Side effects at the patch site, including dermatitis (causing itching, rash, blisters...) and dry skin. Patients experiencing any abnormal conditions during the use of Kefentech should stop using and promptly notify the doctor for instructions.
6. Be careful when using Kefentech
Kefentech topical paste is similar to other anti-inflammatory and pain-relieving drugs that are only used for the purpose of reducing symptoms, not specifically treating or treating the cause of the disease. In cases of painful arthritis accompanied by infection, patients using Kefentech paste should be closely monitored for drug use, and consider the combination of appropriate antibiotics and antifungal drugs. Patients using Kefentech patches should be aware of the risk and symptoms of infection. When using Kefentech paste in combination with systemic anti-inflammatory drugs for the treatment of chronic diseases (such as rheumatoid arthritis) needs to be carefully considered. If combined, the doctor needs to have a plan to closely monitor the patient, paying special attention to possible side effects. The safety of Ketoprofen paste in children has not been adequately studied to date. Patients should limit exposure to direct sunlight on the skin covered with Kefentech. Do not apply Kefentech to the skin near the eyes or directly to the eyes and mucous membranes. Kefentech should be used with caution in open wounds, as it may lead to temporary pain or skin irritation. Besides, when applying Kefentech, the patient should not cover the wound. The safety of Kefentech paste when used for pregnant women has not been fully studied, so it is best to ensure that pregnant patients do not use Kefentech or if using it. Do not stick it on the skin for a long time. In addition, there are no reports on the use of Kefentech paste during lactation. Kefentech is used for the symptomatic treatment of conditions such as deforming arthritis, rheumatoid arthritis, humeral-shoulder periarthritis (with pain, stiffness, and numbness in the shoulder), tendon sheath inflammation. or tendonitis and relieve muscle pain. In addition, Kefentech is also used to treat swelling and pain caused by trauma. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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