Tolazamide: Uses, indications and cautions when using

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Tolazamide is used with an appropriate diet and exercise program to control blood sugar in patients with type 2 diabetes. Tolazamide belongs to the group of drugs called sulfonylureas. It works to lower blood sugar by releasing your body's natural insulin.

1. Indications and contraindications of Tolazamide

Tolazamide is indicated in the treatment of:
Type 2 diabetes Tolazamide is contraindicated in the following cases:
Low blood sugar Pituitary hormone deficiency Addison's disease Acidosis, high acid levels in the blood Metabolism disorder Liver porphyrias Alcoholism Liver disease Accumulation of toxins in the blood due to kidney failure called urethritis Decreased kidney function Fever above 38.5 degrees C Severe nausea and vomiting for a long time Weak patient.

2. How to use Tolazamide

Take Tolazamide by mouth with the first breakfast or meal of the day as directed by your doctor, usually once a day. Some patients, especially those taking higher doses, may be directed to take Tolazamide twice a day in the morning and evening. The dose of Tolazamide is calculated by your doctor based on your medical condition and response to treatment. Use Tolazamide regularly to get the most benefit from it. To help you remember to take your medication, take it at the same time(s) each day, Lab tests or medical tests (such as liver and kidney function tests, fasting blood sugar, hemoglobin A1c, complete blood count) should be performed periodically to monitor your progress or check for side effects while you are on Tolazamide treatment. Tell your doctor if your condition does not occur. improves or if it worsens (your blood sugar is too high or too low) after using Tolazamide.

3. Tolazamide side effects

Tolazamide side effects are listed below by likelihood.
Common side effects of Tolazamide include:
Low blood sugar Weight gain Excessive urination Constipation Drowsiness Dizziness Decreased appetite Decreased appetite Increased hunger Headache Nausea Vomiting heartburn Diarrhea Co stomach tightening. Uncommon side effects of Tolazamide include:
Erythema multiforme Skin rash with peeling. Rare side effects of Tolazamide include:
Endocrine and metabolic disorders Liver Porphyrin metabolism disorders Hemolytic anemia Thrombocytopenia Low blood count due to myelosuppression Thrombocytopenia Low white blood cell count Eosinophils acidosis Blood disorders Hepatitis Bile duct obstruction Skin increased sensitivity to sunlight Itching, skin rash. This is not a complete list of Tolazamide possible side effects. If you notice other side effects of the medicine not listed above, contact your doctor immediately.

4. Measures to prevent side effects of Tolazamide

Before taking Tolazamide, tell your doctor if you are allergic to this medicine and any other allergies you may have. Tolazamide products may contain ineffective ingredients that may cause allergic reactions or other problems. Tell your doctor your medical history, especially of: Kidney disease, liver disease, thyroid problems, certain hormone conditions (adrenal or pituitary insufficiency, antiretroviral syndrome) inappropriate urination - SIADH ), electrolyte imbalance (low blood sodium levels). You may experience blurred vision, dizziness, or drowsiness while using Tolazamide because your blood sugar is too low or too high. Therefore, you should not drive, use machines, or perform any activity that requires alertness or clear vision while being treated with Tolazamide, until you are sure you can do it. these operations safely. Limit alcohol while taking e-drugs, as it may increase the risk of developing complications of hypoglycemia. It can be harder to control blood sugar when your body has another illness like a fever, infection, injury, or surgery. You then need to consult your doctor as this may require a change in your diabetes treatment plan. Tolazamide may make you more sensitive to the sun. Limit your time in the sun, use sunscreen, and wear protective clothing when out in the sun. Before surgery, tell your doctor or dentist that you are treating your diabetes with Tolazamide. Older adults may be more sensitive to the side effects of tolazamide, especially those with low blood sugar. Tolazamide should be used during pregnancy only when clearly needed. Discuss the risks and benefits of Tolazamide with your doctor. Your doctor may change your diabetes treatment during pregnancy. Currently, it is not known whether Tolazamide passes into breast milk. However, drugs similar to Tolazamide do pass into breast milk, so women who are breastfeeding should consult their doctor before using this medicine.

5. Tolazamide drug interactions

Drug interactions can change the way Tolazamide works or increase your risk of serious side effects. Tell your doctor about all prescription drugs, over-the-counter medicines, and herbal products you are using. Do not start, stop, or change the dose of any medicine while being treated with Tolazamide, without your doctor's approval.
Beta blockers (like Metoprolol, Propranolol, glaucoma eye drops like Timolol)

6. What to do if you overdose or forget to take Tolazamide?

Tolazamide overdose symptoms may include: Tremor, heart palpitations, sweating, loss of consciousness, seizures. If you or someone else has overdosed on Tolazamide and has severe symptoms such as fainting or difficulty breathing, call 911 right away.
If you miss a dose of Tolazamide, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose, take your next dose of Tolazamide at the usual time, and do not take a double dose.

7. How to store Tolazamide

Store Tolazamide at room temperature, away from light and moisture, do not store in the bathroom, keep it away from children and pets. Dispose of the Tolazamide product appropriately when it has expired or is no longer needed by you.

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Reference source: Webmd.com