Motegrity: Uses, indications and precautions when using

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Motegrity is used to treat chronic constipation. This medication is usually used when other constipation medications (such as laxatives) don't work. Motegrity works by improving how well your stomach and intestines move food through the intestines during digestion.

1. Indications and contraindications of Motegrity

Motegrity is indicated for the treatment of:
Chronic idiopathic constipation Motegrity is contraindicated in the following cases:
Suicidal thoughts Depression Crohn's disease Toxic ulcerative colitis Megacolon Intestinal obstruction due to decreased peristaltic movement Stomach or intestinal obstruction Women who are breast-feeding Stomach or intestinal wall rupture Chronic kidney disease stage 4, 5. Renal disease with potential for impaired kidney function. 2. How to take Motegrity Read your doctor's instructions carefully before you start taking Motegrity and each time you get a supplement. If you have any questions about how to use Motegrity, ask your doctor.
Motegrity is to be taken by mouth with or without food as directed by your doctor, usually once a day. Dosage is based on your age, medical condition, and response to treatment. The usual Motegrity dose is 2 milligrams per day.
Use Motegrity pills regularly to get the most benefit from it. To avoid forgetting to take your medicine, take it at the same time each day.
Tell your doctor if your constipation does not improve after 3 to 4 days. Your doctor may recommend that you temporarily take another supplement (such as a stimulant laxative) along with Motegrity for quick relief from constipation. If a supplement is recommended, carefully follow your doctor's instructions for use. Ask your doctor for how long you should continue to take this and/or other constipation medicines.

3. Side effects of Motegrity

During the use of Motegrity, you may experience nausea, abdominal pain, diarrhea or headache which usually occurs during the first 1 to 2 days of treatment. Dizziness or fatigue may also occur. If any of these side effects persist or get worse, tell your doctor right away.
Remember that your doctor has prescribed this medicine for you because they have judged that the benefit to you is greater than the risk of side effects. Many people use Motegrity and no serious side effects occur.
Tell your doctor right away if you have any serious side effects of Motegrity, including: Fast/irregular heartbeat.
Stop using Motegrity and get medical help right away if you have any very serious side effects of the medicine, including: Severe/persistent stomach pain, bloody diarrhea, rectal bleeding mental changes (such as depression, thoughts of suicide or hurting yourself).
A very serious allergic reaction to Motegrity is very rare. However, if you notice any symptoms of a serious allergic reaction to Motegrity, including: Hives, itching/swelling (especially of the face/tongue/throat), trouble breathing, severe dizziness important, get medical help right away.
Below are Motegrity side effects by likelihood.
Common side effects of Motegrity include:
Dizziness Low Energy Headache Nausea Vomiting Vomiting Stomach bloating Diarrhea Severe abdominal pain Rare side effects of Motegrity include:
Spontaneous behavior Suicidal thoughts Self-harming thoughts Nightmares Migraines Itching Difficulty sleeping Skin rashes Puffy face due to water retention Decreased appetite Increased need to urinate often Anxiety This is not a name Full list of possible side effects of Motegrity. If you notice other side effects of the medicine not listed above, contact your doctor immediately.

4. Measures to prevent side effects of the drug Motegrity

Before taking Motegrity, tell your doctor if you are allergic to this medicine and any other allergies you may have. Motegrity products may contain ingredients that do not work (such as lactose ) and these may cause allergic reactions or other problems.
Before using Motegrity, tell your doctor your medical history, especially of: Diabetes, heart problems (such as irregular heartbeat, previous heart attack), kidney problems , liver disease, mental/mood problems, other stomach/abdominal disorders (such as bowel perforation, bowel obstruction, Crohn's disease, ulcerative colitis).
Motegrity can make you dizzy and alcohol and marijuana can make you more dizzy. Do not drive, use machines, or do anything that requires alertness while using Motegrity, until you can do so safely.
Before surgery, tell your doctor or dentist that you are being treated with Motegrity.
Women who take oral contraceptives should use another method of birth control if severe diarrhea occurs, because then your body may not be able to fully absorb the Pill.
During pregnancy, women use this medicine only when clearly needed. Talk to your doctor about the risks and benefits of the drug for you. Motegrity passes into breast milk therefore women who are breastfeeding should consult their doctor before use.

5. Interactions of drugs Motegrity

Drug interactions can change the way Motegrity works or increase your risk of serious side effects. Tell your doctor about all the medicines you use (including prescription/nonprescription drugs and herbal products). Do not start, stop, or change the dose of any medicine while using Motegrity, without your doctor's approval.
One product that may interact with Motegrity is: Pramlintide.

6. What to do when overdose or forget to take Motegrity?

If you or someone else has overdosed on Motegrity and has severe symptoms such as fainting or difficulty breathing, call 911.
If you miss a dose of Motegrity, take it as soon as you remember. If you remember when it is almost time for your next dose, skip the missed dose. Take your next dose of Motegrity at the usual time, do not double the usual dose.

7. How to store the drug Motegrity

Store Motegrity in its original packaging at room temperature away from light and moisture, do not store in the bathroom, and keep it away from children and pets. Dispose of the Motegrity product appropriately when it has expired or is no longer needed.

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Reference source: webmd.com