Risk of osteoporosis in patients with psoriasis

Psoriasis is an autoimmune disease, which is a skin condition where patches of red and scaly skin appear. In addition, psoriasis increases the risk of osteoporosis.
Researchers from Rome's Sapienza University looked for signs of osteoporosis in 43 patients with psoriasis. According to the results, 60% of the patients developed osteoporosis, while 18% of these progressed to osteoporosis.
Among the patients participating in the study, the risk of osteoporosis and osteoporosis increased the longer someone had psoriasis, specifically by 5% per year since diagnosis.
Although osteoporosis is generally considered to affect women more than men. However, researchers determined that men are more likely to develop osteoporosis than women. Patients with psoriasis, especially if they have had psoriasis for a long time, appear to be at increased risk of developing osteoporosis. Therefore, patients with psoriasis, especially those with a long history of the disease, should have a bone density test to evaluate for osteoporosis.

The researchers also note that the inflammation caused by psoriasis may be one reason patients are at higher risk for osteoporosis. Certain inflammatory cytokines or proteins associated with psoriasis have also been implicated in osteoporosis.
Osteoporosis is more common in people with psoriatic arthritis than in people with psoriasis alone. This is due to increased joint pain and inflammation.

Even if psoriasis patients already have osteoporosis, there are many ways that can help prevent osteoporosis and rebuild bone.
2.1. Medications Drugs that prevent or reduce fractures such as:
Bisphosphonates: These drugs can reduce osteoporosis-related fractures, but the effectiveness of each varies. Certain drugs are better at preventing broken bones. Alendronate (Binosto, Fosamax) Ibandronate (Boniva) Risedronate (Actonel, Atelvia) Zoledronic acid (Reclast, Zometa)

2.2. Estrogen therapy This estrogen therapy for osteoporosis works well in reducing bone loss, fractures in the hip and spine. However, this therapy also has many disadvantages. Although it replaces the plummeting estrogen levels during menopause, it can also increase the risk of blood clot formation, heart attack, breast cancer, and stroke. Therefore, when using the patient should consult a doctor.
2.3. SERMs (Selective Estrogen Receptor Modulators) These drugs provide patients with the benefits of estrogen therapy without many of the downsides. Raloxifene (Evista) is the only SERM approved for the treatment of osteoporosis. It can reduce the risk of spinal fractures.
2.4 Bone growth Abaloparatide (Tymlos) and teriparatide (Forteo) are drugs that help with bone growth. In women, they help reduce fractures of the spine, arms, and legs. This medication is also used for men with low testosterone levels and steroid-induced osteoporosis. With either drug, the patient has to inject it every day, making the treatment very expensive.
Also, the drugs Miacalcin and Fortica have been around since the 1980s. They help prevent osteoporosis and reduce spine fractures.

There are different options for the treatment and prevention of osteoporosis. However, patients should consult their doctor about using any medication to avoid unwanted side effects.
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Articles refer to sources: psoriasis.org, webmd.com