Uses of Inderal

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1. What is Inderal?

Propranolol Inderal drug is used in the treatment of cardiac arrhythmias, angina pectoris, frequency and severity of migraine, hyperthyroidism, tremors,... The drug has antihypertensive effect. , thereby helping to prevent strokes, heart attacks and some kidney problems.
Inderal is a non-selective beta-adrenergic blocker. It works by blocking certain natural substances in the body (such as epinephrine) from affecting blood vessels and the heart, reducing cardiac output, inhibiting the release of renin by the kidneys, and blocking sympathetic nerves from the heart. vasomotor centers in the brain come out. This helps lower blood pressure, lower heart rate, and reduce stress on the heart.
Inderal treats angina by reducing myocardial oxygen demand by blocking the effect of catecholamines in increasing heart rate, reducing systolic blood pressure, and decreasing the rate and extent of myocardial contraction. Inderal also works to reduce and prevent migraine by acting on beta-adrenergic receptors in vessels on the brain lining. Thus blocking the vasoconstriction of the cerebral arterioles. In hyperthyroidism, Inderal reduces T3 levels, and has no effect on T4. Inderal drugs also have the effect of reducing portal pressure, reducing the collateral-host blood flow in patients with cirrhosis. Inderal is effective in physiological tremor and essential tremor. Inderal is almost completely absorbed from the gastrointestinal tract. After taking 30 minutes appear in the blood plasma and after 60 - 90 minutes reach the maximum concentration. The drug readily crosses the blood-brain barrier, enters the placenta and is distributed in breast milk. Almost completely metabolized in the liver, excreted in the feces.

2. Indications and contraindications of the drug Inderal

2.1. Indications Inderal drug is indicated in the following cases: Hypertension, angina pectoris due to coronary atherosclerosis. Arrhythmia (suppressive supraventricular tachyarrhythmia). Half head pain. Essential tremor. Inferior aortic stenosis due to hypertrophy. Adrenal myeloma. Prevent sudden cardiac death, after acute myocardial infarction; adjuvant treatment of arrhythmias and tachycardia in patients with short-term hyperthyroidism (2-4 weeks). Prevention of recurrent bleeding in patients with portal hypertension and esophageal varices. 2.2. Inderal is contraindicated in the following patients:
Patients with asthma, heart failure, first and second degree atrioventricular block, bradycardia (less than 50 beats/min), shock heart. Right ventricular failure due to pulmonary hypertension Congestive heart failure. Peripheral circulatory disorders. Adrenal myeloma.

3. Be careful when using Inderal

During the use of Inderal, the patient should pay attention to the following issues:
Avoid using Inderal in case of obvious heart failure, but can be used when the signs of heart failure have been controlled. Due to the effect of slowing the heart rate, if the heart rate is too slow, the dose should be reduced. In patients with ischemic heart disease, the drug should not be stopped abruptly. Dosage reduction and monitoring of renal or hepatic function test results are required for long-term Inderal users. Caution should be taken when using Inderal for pregnant and lactating women, and should consult a doctor.

4. Dosage and how to take Inderal

The drug Inderal is taken orally. Dosage is based on the patient's medical condition. Refer to the dose of Inderal in the following article:
Increase BP 40 - 80 mg x 2 times/day. Angina 10 - 20 mg x 3-4 times / day, may increase every 3-7 days; Average: 160mg/day. Arrhythmia 10 - 30 mg x 3 - 4 times/day. Migraine 40mg x 2 times/day, average 80-160 mg/day. Inferior aortic stenosis due to hypertrophy 20-40 mg x 3 - 4 times/day. Adrenal myeloma 60mg/day, divided into several times before surgery. Malignant case: 30mg/day, divided into several times. Dosage for essential tremor: Initial dose: 40mg x 2 times/day. Usually a good effect is achieved with a dose of 120mg. Note: It should be noted that the above drug dosage is for reference only, so patients need to strictly follow the instructions and instructions of the doctor to achieve the highest treatment effect.

5. Side effects of the drug Inderal

During the use of Inderal, patients may experience some of the following side effects:
Cardiovascular:
Bradycardia, Congestive heart failure, atrioventricular block. Lower blood pressure. Thrombocytopenia purpura. Arterial hypoperfusion is usually Raynaud's. Nervous system:
When long-term treatment with high doses may experience: mild headache, dizziness, ataxia, excitability, hearing loss, visual disturbances, hallucinations, confusion, insomnia, fatigue, weakness, depression. Physical brain syndrome manifests as disorientation in time and space, decreased short-term memory, and emotionality. Paresthesias in the hands, peripheral neuropathy. Allergic: Pharyngitis, granulocytopenia, erythema, fever accompanied by sore throat, laryngospasm, acute respiratory failure.
Respiratory: Bronchospasm .
Blood: Agranulocytosis, thrombocytopenic purpura, or no thrombocytopenia.
Digestive: Nausea, vomiting, abdominal cramps, epigastric pain, diarrhea, constipation, flatulence.
In addition, there are some rare side effects such as: systemic lupus erythematosus, hair loss, dry eyes, impotence. Therefore, if you experience any unusual side effects, the patient should promptly notify the doctor or go to the medical center for examination and treatment.
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