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Asmin contains the main ingredients are Theophylline anhydrous, Phenobarbital, Ephedrine hydrochloride and excipients just enough for one pill. The drug is used in the treatment of bronchial asthma, shortness of breath caused by asthma.
1. What is Asmin?
Asmin medicine contains the main ingredients:
Theophylline 109 mg, this active ingredient belongs to the group of bronchodilators. Phenobarbital 8mg, this active ingredient belongs to the group of Barbiturates. Ephedrine hydrochloride 25mg, this active ingredient belongs to the sympathomimetic group. Asmin medicine combines the above 3 ingredients and excipients just enough for one pill, helping to treat bronchial asthma, shortness of breath due to asthma thanks to the following mechanism of action:
Relaxing bronchial smooth muscle. Sedative effect, relieves muscle spasms, reduces anxiety. Bronchiectasis, increased air flow through the bronchi, alveoli, stimulation of the respiratory center.
2. In what cases is Asmin indicated?
Asmin is indicated for use in the following cases:
Paroxysmal bronchial asthma. Bronchial asthma with persistent difficulty breathing. Bronchospasm . The spastic form of chronic obstructive pulmonary disease (COPD).
3. Contraindications of Asmin
Asmin drugs are not used in the following cases:
Patients with hypersensitivity to any ingredient of Asmin medicine. Patients with Porphyria Metabolism Disorders. Patients with respiratory failure, severe liver failure. Patients with peptic ulcer disease, convulsions, uncontrolled epilepsy. Patients with high blood pressure, hyperthyroidism, hypokalemia or being treated with antidepressants (monoamine oxidase inhibitors). Drug addicts, alcoholics.
4. Dosage and usage of Asmin
Asmin drug use as prescribed by the doctor and the instructions for use on the package. Asmin medicine is prepared in the form of tablets, used orally, when swallowed whole, do not crush the drug. Asmin should be taken with a glass of water on an empty stomach 1 hour before a meal or 2 hours after a meal. Patients take Asmin at the same time to ensure the correct dose and effectiveness.
As soon as the symptoms are relieved, the patient must not stop taking the drug on their own, but must follow the doctor's instructions.
Dosage of Asmin:
Adults: 1 tablet x 3 times/day 4 hours apart. Reduce dose in patients with angina pectoris, heart failure, viral infections, cirrhosis or liver failure, elderly. Children: No dose studies have been performed.
5. Undesirable effects of Asmin
When using Asmin, patients may experience the following undesirable effects:
Cardiovascular system: Tachycardia, palpitations. Nervous system: Dizziness, headache, sweating, agitation, seizures, somnolence, nystagmus. Musculoskeletal system: Ataxia, osteomalacia, muscular dystrophy, arthralgia. Digestive system: Nausea, vomiting. Skin: Erythema, Lyell's syndrome (maculopapular, diffuse erythema on the skin), allergic reactions. Blood: Macrocytic anemia. Other side effects not listed may also occur in some patients taking Asmin. If the patient experiences any other side effects, contact the doctor immediately for appropriate treatment.
6. Some notes when using Asmin
Patients taking Asmin should be cautious of the following:
Use Asmin with caution in people with peptic ulcer, hyperthyroidism, glaucoma, diabetes, decreased blood oxygen levels, hypertension, epilepsy, people with angina or damage to the heart muscle, patients taking cardiovascular drugs Digitalis. Theophylline should not be administered intravenously to patients taking Asmin, and should not be used concurrently with other xanthine bronchodilators. Patients need to inform the doctor about the drugs they are using (if any) to avoid drug interactions causing unwanted effects. Asmin may cause difficulty urinating in an enlarged prostate. Asmin should not be used for children < 3 years old, not more than 7 days in a row. Pregnancy and lactation: Asmin crosses the placenta and is excreted in breast milk, so it is not recommended for pregnant and lactating women. For people who are driving and operating machinery: Because the drug can cause headaches and dizziness, people who are driving and operating machinery using the drug should be careful.
7. Asmin can interact with which drugs?
Asmin can interact with some drug groups causing decreased effectiveness as well as increased side effects of the drug. Therefore, the patient needs to inform the treating doctor about the medical history, the drugs being used to have the appropriate treatment method.
Asmin drug interactions include:
Cimetidine, high doses of Allopurinol, oral contraceptives, Propranolol and some antibiotics (Ciprofloxacin, Erythromycin, Fluvoxamine and Troleandomycin) can increase the concentration of Asmin in the blood, increase the effect. unwanted use. Rifampicin may decrease blood levels of Asmin. Concomitant administration of Asmin with Phenytoin, Carbamazepine or Barbiturates may result in decreased efficacy of one or two drugs. Methotrexate may decrease the clearance of Asmin, may reduce effectiveness, increase undesirable effects of the drug. Concomitant use of Asmin with Dexamethasone increases the elimination of Dexamethasone, reducing the effectiveness of the drug. Taking Asmin with sodium bicarbonate or other urine alkalinizers can lead to Ephedrine toxicity. Concomitant use of Asmin with antidepressants (non-selective mono amino oxidase inhibitors) is associated with a risk of paroxysmal hypertension, hyperthermia, and possibly death. Asmin reduces the concentration, reduces the effectiveness of some antibiotics, systemic corticosteroids, heart arrhythmia drugs (Quinidin), thyroid hormone drugs, immune drugs, high blood pressure drugs, anti-dynamic drugs. menstruation, oral anticoagulants. The use of Asmin is to relax bronchial smooth muscle, reduce bronchospasm in the prevention and control of bronchial asthma as well as some other chronic lung diseases. Patients need to know the information about the drug, discuss with the specialist to get better treatment effect.
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