What is Orenko 200mg?

Orenko is a medicine used to fight infections, fungi, viruses and parasites. The drug is often indicated for the treatment of uncomplicated urinary tract infections, gonorrhea, pharyngitis, tonsillitis, otitis media,...

The active ingredient Orenko is Cefixime trihydrate. Active ingredient Cefixim has effects on gram-negative and gram-positive bacteria such as: Streptococcus pneumoniae S.pneumoniae, Escherichia coli (E. coli), H.influenzae (Hib), Neisseria gonorrhoeae,... making bacteria unable to divide and die.
Orenko Cefixim 200mg is indicated in the following cases:
Uncomplicated gonorrhea caused by gonorrhea N.gonorrhoeae; Tonsillitis and pharyngitis caused by S. pyogenes ; Urinary tract infections (nephritis, acute pyelonephritis, acute cystitis); otitis media ; Tonsillitis and pharyngitis are caused by bacteria sensitive to the drug.

Orenko drug is taken directly orally. The patient swallows the tablet directly with water without breaking, crushing or dissolving the tablet.
For adults, the recommended dose is 400mg/day, taken once or in two divided doses. Time to take each dose 12 hours apart; For children, the recommended dose for children 6 months - 12 years old (weighing less than 50kg) is 8mg/kg, given once or divided into 2 oral doses. For children over 12 years old (weighing over 50kg) the dose and duration are similar to adults. Treatment of uncomplicated gonorrhea: Take 400mg/time, use a single dose. Treatment of disseminated gonorrhea: Inject antibiotics (Cefotaxim, Ceftriaxon, Spectinomycin,...) then use Orenko at a dose of 400mg/divide 2 times/day and treat for 1 week. If during treatment, the patient finds that the usual dose does not respond to symptoms, it is necessary to talk to the doctor to have the dose adjusted or to review the original diagnosis.

In some cases, Orenko Cefixim 200mg can cause some side effects during use. If side effects arise, the patient should actively report to the doctor for professional advice:
Digestive disorders:
Abdominal pain; Diarrhea; Passing rotten stools; Nausea and vomiting; Dry mouth ; Not eating well; Bloating. Usually, digestive disorders only occur within 1-2 days of taking the drug. Therefore, the patient does not need to treat the above symptoms.
Other common side effects:
Headache, dizziness; Jitter; Insomnia; Tired.

Uncommon side effects:
Severe diarrhea; Lyell's syndrome (Toxic epidermal necrolysis); Steven-Johnson syndrome ; Erythema multiforme; Angioedema; Anaphylactic reactions; Decrease in white blood cells, platelets, decrease in hematocrit and hemoglobin levels; Inflammation and yeast infection (Candida); Acute renal failure; Liver damage causes jaundice.

Orenko is contraindicated in the following cases:
Hypersensitivity to Cephalosporin antibiotics, Penicillin antibiotics and drug components; Children under 6 months old; Pregnant and lactating women; Some cautions when taking Orenko:
Patients with renal failure need to adjust the dose to avoid damage and impaired renal function. Use caution when using Orenko for people with a history of gastrointestinal problems. The active ingredient Cefixime in the medicine may increase the risk of overgrowth of resistant bacteria – especially Clostridium difficile in the intestinal tract. When the amount of Clostridium difficile bacteria in the body increases rapidly, a person can develop severe diarrhea. In this case, it is necessary to stop taking the drug and switch to other antibiotics such as vancomycin. However, if the diarrhea only lasts for about 2 days, this is probably a common side effect of Orenko and you don't need treatment.

Orenko Cefixim 200mg drug may interact with the following drugs:
Probenecid: Reduces renal clearance and volume of distribution of Cefixime, thereby increasing the effect of Orenko drug. Carbamazepine: Cefixime increases the concentration of Carbamazepine in the blood; Warfarin Anticoagulants: Increases prothrombin time and may or may not be accompanied by bleeding symptoms. Nifedipine: Increases the bioavailability of the active substance Cefixime. Above, full information about Orenko medicine has been shared by Vinmec International General Hospital. If you have any questions about Orenko medicine, please ask your doctor directly for quick and timely answers. The above information is for reference only and is not intended to replace the instructions of a qualified medical practitioner.