What is Choline Alfoscerate 400mg?

Choline alfoscerate 400mg has the main active ingredient is choline alfoscerate with 400mg content. The drug is often used in the treatment of dementia, memory loss, Alzheimer's disease, rehabilitation after stroke, traumatic brain injury, ...

What is Choline alfoscerate 400mg? Choline alfoscerate 400mg has the main active ingredient is choline alfoscerate with a strength of 400mg. The drug has the effect of inhibiting acetylcholinesterase, which enhances the synthesis of acetylcholine and phospholipids of neuronal membranes. The drug helps support the treatment of dementia, helps improve memory, restores nerve function due to age-related brain damage, chronic vascular disease, stroke, after traumatic brain injury or Stroke .
Choline is rapidly absorbed and distributed throughout the body, peak concentrations are reached about 1 hour after oral administration. Choline alfoscerate is extensively metabolized. Part of the drug is absorbed across the blood-brain barrier and aids in the synthesis of acetylcholine. Choline alfoscerate reaches high concentrations in breast milk. Choline alfoscerate is eliminated mainly in the urine as metabolites, only about 4% is eliminated as unchanged drug.

Choline alfoscerate 400mg drug is indicated in the following cases:
Decreased concentration and dementia due to diseases such as acute cerebrovascular disease, Alzheimer's disease, memory loss in the elderly. Rehabilitation after stroke Traumatic brain injury, support for recovery after trauma, neurosurgery Memory impairment Apathy, disorientation Decreased ability to function, movement Brain impairment Headache, dizziness , dizzy Confusion

Choline alfoscerate is contraindicated in the following cases:
Hypersensitivity to any ingredient of the drug Pregnant women Lactating women.

Adults take 1 tablet / time, take 2-3 times a day and use for 4 weeks. The duration of use of the drug may be prolonged depending on the clinical response of the patient or as directed by the physician.

Common side effects when using Choline alfoscerate are rash, hives, headache, insomnia, heartburn.

During the use of Choline alfoscerate, patients should pay attention to the following issues:
The following subjects need to be cautious when using Choline alfoscerate: Patients with intestinal or urinary tract obstruction, asthma and obstructive airway disease, cardiovascular disorders including bradycardia or myocardial infarction, hypotension, hyperthyroidism, peptic ulcer disease. Note when driving and operating machinery: Because Choline alfoscerate has side effects such as headache, insomnia. Therefore, patients should be cautious when operating machinery or driving while taking the drug. Overdose and treatment: There is no information on overdosage of Choline alfoscerate with long-term use. In case the patient takes the wrong drug with a high dose, nausea, vomiting, diarrhea or difficulty breathing may occur. Management includes: immediate gastric lavage and symptomatic treatment, possibly with atropine 0.5 - 1 mg or epinephrine 0.1 - 1 mg intravenously or subcutaneously. Missed dose and treatment: If you forget to take a dose of Choline alfoscerate, take it as soon as you remember. However, it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. In summary, Choline alfoscerate has the role of inhibiting acetylcholinesterase, helping to enhance the synthesis of acetylcholine and phospholipids of neuronal membranes. The drug is used in the treatment of dementia, memory enhancement, neurological rehabilitation due to age-related brain damage, chronic vascular disease, stroke, post-traumatic brain injury or brain accident. Patients should not self-medicate, but should consult a specialist before using.
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