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Lansolek medicine has the main active ingredient Lansoprazole with a content of 30mg in the form of Lansoprazole microparticles that are coated in the intestine. The dosage form of the drug is a hard capsule containing lansoprazole microparticles coated in the intestine, suitable for direct oral use. Packing is a box of 10 blisters and each blister contains 10 hard capsules. Lansolek belongs to the group of drugs that treat diseases of the gastrointestinal tract.
1. What is Lansolek?
Lansolek medicine has the main active ingredient Lansoprazole with a content of 30mg in the form of Lansoprazole microparticles that are coated in the intestine. The dosage form of the drug is a hard capsule containing lansoprazole microparticles coated in the intestine, suitable for direct oral use. Packing is a box of 10 blisters and each blister contains 10 hard capsules. Lansolek belongs to the group of drugs that treat diseases of the gastrointestinal tract.
1.1. Pharmacodynamics of the main active ingredient Lansoprazole's main active ingredient is a benzimidazole derivative with anti-secretory effects on gastric acid. The mechanism of action of the drug Lansoprazole is to inhibit the proton pump of the gastric mucosa, so this drug is used to treat peptic ulcers and long-term treatment of hypersecretion. pathological digestion. The main active ingredient Lansoprazole has the effect of inhibiting gastric acid secretion mainly and when stimulated by any stimulant. The degree of inhibition of gastric acid secretion depends on the dose and duration of treatment. However, the active ingredient Lansoprazole inhibits acid secretion better than H2-receptor antagonists. Lansoprazole is also used to treat gastritis caused by Helicobacter pylori infection when combined with one or more anti-infective drugs. If combined with one or more anti-infective drugs, specifically Amoxicillin, Clarithromycin, Lansoprazole-containing drugs can be effective in eradicating stomach infections caused by H.pylori. 1.2. Pharmacokinetics of the active ingredient Lansoprazole Active ingredient Lansoprazole is rapidly absorbed from the gastrointestinal tract, bioavailability is about 80%. Taking Lansoprazole after a meal reduces the concentration of the drug in the blood by 50%. Active ingredient Lansoprazole is about 97% bound to plasma proteins. Peak plasma concentrations are reached approximately 1.7 hours after oral administration. Lansoprazole is extensively metabolised in the liver to two major metabolites, the sulfone of lansoprazole and the hydroxy lansoprazole. These two metabolites have little or no anti-acid effect. About 20% of the active substance Lansoprazole is excreted in bile and urine. The mean elimination half-life in healthy subjects is approximately 1.5 hours, and the elimination of lansoprazole is prolonged in subjects with severe liver disease but is unchanged in those with severe renal impairment.
2. What disease does Lansolek treat?
What disease does Lansolek treat? Lansolek medicine 30mg is used in the treatment of specific diseases as follows:
Treatment of erosive esophagitis in people with gastroesophageal reflux disease. Treat heartburn regularly. Treatment of acute gastric and duodenal ulcers caused by infection with or without infection with H.pylori bacteria. Treatment of specific pathological hypersecretory conditions such as Zollinger-Ellison syndrome, polyendocrine tumors, systemic mastocytosis. Treatment of peptic ulcers caused by the use of non-steroidal anti-inflammatory drugs or NSAIDs.
3. Usage and dosage of the drug Lansolek
3.1. How to use Lansolek Lansolek drug is prepared in the form of hard capsules containing Lansoprazole microparticles coated in the intestine, suitable for direct oral use. You should take the pill in the morning before eating, do not break or chew the tablet when using. 3.2. Dosage of the drug Lansolek Dosage to treat ulcerative esophagitis: Adults take 30mg / time / day, for a period of 4 to 8 weeks and can be used for another 8 weeks, if not cured. Maintenance dose 15mg/day. Dosage for treatment of gastric ulcers is 15-30mg/time/day, used for 4 to 8 weeks. Dosage for duodenal ulcer treatment is 15mg/time/day, used for 4 weeks or until the disease is cured. Dosage to treat other hypersecretory such as Zollinger - Ellison syndrome needs to be used 60mg / time / day. It should be noted: The above drug dosage is for reference only, patients need to take the drug exactly as prescribed by the doctor to improve its effectiveness and avoid unwanted side effects.
4. Unwanted effects of the drug Lansolek
During the use of Lansolek, users may experience some undesirable effects, specifically as follows:
The most common reactions to drugs containing Lansoprazole active ingredient are in the gastrointestinal tract such as disturbances. digestion, diarrhea, abdominal pain. In addition, some patients have headache and dizziness. Other common reactions include nausea, vomiting, constipation, dyspepsia, rash. Other rare reactions include fatigue, increased serum gastrin, liver enzymes, hematocrit, hemoglobin, uric acid and proteinuria.
5. Lansolek . drug interactions
Lansoprazole's interactions with other drugs are similar to those of Omeprazole (Prilosec, Zegerid). The absorption of some drugs may be affected by stomach acid levels; The main active ingredient Lansoprazole reduces stomach acid, also reduces the absorption and blood concentration of Ketoconazole (Nizoral) and increases the absorption and blood concentration of Digoxin (Lanoxin). This can lead to decreased effectiveness of Ketoconazole or Digoxin toxicity. Main active ingredient Lansoprazole may increase blood levels of Methotrexate (Trexall) and Tacrolimus (Prograf). The main ingredient Lansoprazole in Lansolek may also increase the effects of Warfarin (Coumadin), leading to an increased risk of bleeding.
6. Some notes when using Lansolek
During the use of Lansolek, patients should pay attention to the following issues:
6.1. Contraindications of the drug Lansolek Contraindicated for people with severe allergies to any of the ingredients of the drug. Persons with a history of hypersensitivity reactions that may include anaphylaxis, anaphylaxis, angioedema, bronchospasm, acute interstitial nephritis, and skin urticaria. 6.2. Precautions while using Lansolek Before using Lansolek, you need to carefully inform your doctor or pharmacist:
If you are allergic to the ingredients of the drug or if you have ever had any reaction any other allergies. This medicinal product may contain inactive ingredients, which could cause allergic reactions or other problems. Medications you are taking include prescription and nonprescription drugs, vitamins, dietary supplements and herbal products. Your medical history if you have had seizures, tumors, heart disease, an overactive or underactive thyroid gland, high blood pressure, liver disease, or if you have a history of abusing alcohol contain alcohol like alcohol. Store Lansolek in a dry place, away from direct light. In addition, it is necessary to keep Lansolek out of the reach of children and family pets. Absolutely do not use the drug Lansolek after the expiry date.
Lansolek medicine has the main active ingredient Lansoprazole with a content of 30mg in the form of Lansoprazole microparticles that are coated in the intestine. Lansolek belongs to the group of drugs for the treatment of diseases of the gastrointestinal tract. Patients should carefully read the instructions for use, consult a doctor / pharmacist before using the drug. Absolutely do not arbitrarily buy Lansolek to treat diseases at home, because there may be unwanted side effects on health.
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