Imipramine: Uses, indications and cautions when using

Imipramine is a commonly used antidepressant medication. In addition, in some cases, Imipramine is also used in combination with other therapies to treat nocturnal enuresis in children.

Imipramine is a medicine that comes in tablets and capsules and is used to treat depression. In addition, Imipramine is also used to prevent bedwetting in children.
Imipramine belongs to the group of tricyclic antidepressants, which treat depression by increasing the amount of natural chemicals in the brain to maintain mental balance. In particular, Imipramine can also help children control nighttime bedwetting, by blocking the effects of a natural chemical (acetylcholine) on the bladder.

When taking imipramine tablets or capsules to treat depression, people can take it one or more times per day, with or without food. When using imipramine tablets to prevent bedwetting in children, it should be taken 1 hour before bedtime. Children with early evening bedwetting may be given 1 dose in the mid-afternoon and another at bedtime.

Some common undesirable effects when taking imipramine are: Dry mouth, blurred vision, headache, drowsiness, dizziness, constipation, nausea, vomiting, loss of appetite, diarrhea, stomach cramps, increased or lose weight and increase sweating. If any of the above effects persist, inform your doctor or pharmacist immediately for appropriate treatment. Tell your doctor right away if other side effects occur while taking imipramine such as: Restlessness, ringing in the ears, sexual problems (reduced sex drive, changes in libido), tremors. , numbness/tingling of hands/feet, pain/redness/swelling of arms or legs, difficulty urinating.

Before taking medicine:
Tell your doctor and pharmacist if you are allergic to imipramine or other medicines. Tell your treating doctor if you are taking a monoamine oxidase (MAO) inhibitor or have stopped taking an MAO inhibitor within the past 14 days. In this case, your doctor will probably tell you not to take imipramine. Tell your doctor and pharmacist what prescription and over-the-counter medicines, vitamins, nutritional supplements and herbal products you are taking or plan to take. Especially drugs such as: Anticoagulants, antihistamines, methylphenidate, muscle relaxants, propafenone, quinidine, sedatives, selective serotonin reuptake inhibitors (SSRIs), and thyroid medications. Tell your doctor if you are being treated with electroconvulsive therapy (a procedure where an electric shock is given to the brain to treat certain psychiatric conditions), and if you have or have ever had an enlarged prostate (prostate gland). male fertility), difficulty urinating, seizures, overactive thyroid, liver, kidney, or heart disease. If you are pregnant, planning to become pregnant, or are breast-feeding, please inform your doctor for a suitable medication plan. If you are having surgery, including dental surgery, tell your doctor or dentist that you are taking imipramine. Prolonged or unnecessary exposure to sunlight should be avoided, and if you must go outside, wear protective clothing, sunglasses and sunscreen as Imipramine can make your skin more sensitive and sunburn. . Discuss with your doctor the risks and benefits of taking imipramine if you are 65 years of age or older. The recommended use of imipramine in the elderly is not as safe and effective as other medications. Imipramine can cause angle-closure glaucoma (a condition where fluid is suddenly blocked and cannot drain out of the eye, causing a rapid increase in intraocular pressure that can lead to vision loss). Therefore, have your eyes checked before you start taking this medicine. Imipramine is a prescription medication and should be taken as directed by your doctor. Patients should absolutely not self-medicate because doing so can increase the risk of experiencing side effects.

Reference source: webmd.com