Scrub-typhus is endemic in many parts of the world, but is more common in countries in the Asia-Pacific region. The disease is caused by an agent called Orientia tsutsugamushi, which has a natural outbreak and is transmitted randomly to humans when bitten by mite larvae.

Scrub typhus originates from a bacterium called Orientalis tsutsugamushi, belonging to the Rickettsia family. The vector is the larva of the tick. In recent years, scrub typhus has tended to appear more frequently after a long period of inactivity. If not treated properly, scrub typhus can cause quite dangerous complications, which can cause liver poisoning or multiple organ damage, even death.