Gastrointestinal stromal tumors (GISTs) are uncommon mesenchymal tumors of the gastrointestinal tract, originating from the interstitial cells of Cajal. GISTs can arise anywhere along the gastrointestinal tract, most commonly in the stomach (50%-60% of cases) or the small intestine (30%-40%), while they are rarely observed in the gastrointestinal tract. esophagus and colon.