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Venlafaxine 75mg medicine is commonly used in the brand name Venlafaxine Stada, belongs to the group of central nervous system drugs in the antidepressant drug subgroup. Let's find out more details about the uses, usage and notes when using Venlafaxine through the following article.1. What is Venlafaxine 75mg?
What is Venlafaxine 75mg? Venlafaxine 75mg belongs to the group of psychotropic drugs with the use to treat mental disorders and to prevent and treat depression and anxiety disorders.
The drug has the main ingredient Venlafaxin in the form of venlafaxin HCl 75 mg. Researched and manufactured at Stada-Vietnam - VIETNAM Joint Venture Company. Venlafaxine 75mg is available as an extended release film coated tablet in a box of 2 blisters x 14 tablets.
2. What are the effects of Venlafaxine 75mg?
Venlafaxine is used in the following cases:
Treatment of depression in inpatients and outpatients including depression with anxiety. Helps prevent recurrence and onset of major depressive episodes. Treatment of anxiety, generalized anxiety disorder, social anxiety disorder including long-term treatment. Treatment of panic disorders, phobias, impulses, post-traumatic stress, agoraphobia with or without.
3. Dosage and how to take Venlafaxine 75mg
The information provided below is not intended to replace medication leaflets or advice from a doctor or pharmacist. Patients should always consult a qualified medical professional before deciding to take Venlafaxine 75mg.
3.1. Venlafaxine 75mg is prepared in the form of capsules and is used orally.
3.2. Dosage The appropriate dose of the drug will depend on the medical condition and the person using the drug. Patients can refer to the following dose of Venlafaxine:
Treatment of major depressive disorder or generalized anxiety disorder:
Initial dose is 75mg Venlafaxine / 1 time / day. After more than 2 weeks of treatment, if there is no response to the drug, the dose can be increased to 75mg Venlafaxin/day, the dose interval is not less than 4 days and the maximum dose is 225mg/day. Treatment of social anxiety disorder:
Start with 75mg Venlafaxin / 1 time / day. Panic Disorder:
Initial dose of Venlafaxin 37.5 mg/day for 7 days, then increased by 75 mg/day after about 2 weeks or more of non-response drug therapy, at intervals of not less than 4 days and the maximum dose is 225mg/day. Elderly:
Use Venlafaxin with caution in the elderly. If used, consider starting from the lowest effective dose and be closely monitored by a doctor or pharmacist when increasing the dose. Patients with hepatic impairment:
Patients with mild to moderate hepatic impairment: The dose should be reduced by 50% of the total daily dose. hemodialysis. Patients with severe hepatic impairment: It is necessary to carefully consider the benefits and risks when using, weighing the potential benefits against the risks of Venlafaxine 75mg treatment.
4. What to do when overdose, forget dose Venlafaxine 75mg?
Venlafaxine 75mg overdose is usually very rare if the patient adheres to the correct dose from the doctor, pharmacist. Cases of overdose occur when taking the drug in combination with alcohol and other drugs. It has been reported that in overdose with Venlafaxin, bradycardia, rhabdomyolysis, QT interval prolongation, bundle branch blockade, prolongation of the QRS interval, sinus and ventricular tachycardia, hypotension, and somnolence have been reported. constipation, seizures, dizziness, liver necrosis and death.
In case of overdose the patient will be managed by ensuring airway clearance, oxygen supply and adequate ventilation. In addition, it is necessary to check the heart rate, treat symptomatically and supportively, possibly using activated charcoal, gastric lavage or induce vomiting. Hemodialysis is not effective in this case, because the hemodialysis clearance of venlafaxine and O-desmethyl venlafaxine are both low.
In case the patient forgets to take a dose of Venlafaxine, take it as soon as you remember, if it is close to the next dose, skip the make up dose and take the next dose as usual. Never double the prescribed dose of Venlafaxine for the purpose of making up for a missed dose.
5. Contraindications to taking Venlafaxine 75mg
Venlafaxine 75mg should not be used in the following cases:
Do not take it at the same time or within 2 weeks after stopping the monoamine oxidase inhibitor. Venlafaxin should be administered at least 7 days prior to treatment with a monoamine oxidase inhibitor. Patients with hypersensitivity to Venlafaxin or any ingredient of the drug. Patients with high cardiovascular risk such as: hypertension, ventricular arrhythmia, ... Children < 18 years old.
6. Venlafaxine 75mg drug interactions with other drugs
Venlafaxine 75mg combined with some other drugs may have drug interactions such as:
Do not combine Venlafaxine with Monoamine oxidase inhibitors (MAOIs) within 14 days of stopping the MAO drug. Possible reactions with the combination of these two drugs have been reported, such as muscle tremors, nausea/vomiting, sweating, flushing, dizziness, and hyperthermia with sedation-like features. malignancies, seizures, and death. Concomitant administration of Venlafaxine with CYP3A4 inhibitors such as Atazanavir, Indinavir, Clarithromycin, Itraconazole, Ritonavir, Voriconazole, Posaconazole, Ketoconazole, Nelfinavir, Saquinavir and Telithromycin may increase the concentration of Venlafaxine and O-desmethylvenlafaxine with caution. Lithium (Treatment of Serotonin Syndrome) with Venlafaxine. Care should be taken when combining Venlafaxine 75mg with other CNS stimulants.
7. Side effects when taking Venlafaxine 75mg
In the process of using Venlafaxine 75mg, patients may experience some unwanted side effects such as:
Mood, behavior changes Anxiety Panic Difficulty sleeping Working in a hurry is difficult to do slowly Easy agitated, hostile, restless, aggressive, depressed Thoughts of suicide, self-harm. Severe:
Convulsions Very stiff muscles, high fever, tremors, sweating, confusion, fast or irregular heartbeat, feeling of fainting. Agitation, tachycardia, hallucinations, fever, overactive reflexes, diarrhea, nausea, vomiting, loss of coordination. Headache, trouble concentrating, weakness, memory problems, feeling unsteady, fainting, confusion, hallucinations, shallow breathing or stopping breathing. Cough, chest tightness, trouble breathing Easy bruising. Less severe:
Feelings of anxiety, restlessness, dizziness, drowsiness. Having strange dreams Increased sweating Blurred vision Dry mouth Appetite, Weight change Mild nausea, constipation Decreased libido, impotence, or difficulty reaching orgasm. However, not all patients experience these side effects. In the process of use may encounter other effects not mentioned. If the patient has any questions about side effects, consult a qualified medical professional.
8. Precautions when using Venlafaxine 75mg
Caution should be exercised in patients with depression, as there may be a risk of suicide. Only prescribe Venlafaxin in small amounts to keep the patient well controlled and reduce the chance of an overdose. Care should be taken to use in patients with a history of myocardial infarction, increased heart rate. Due to the risk of hypertension with Venlafaxine dosing and treatment monitoring is required. During long-term Venlafaxine 75mg treatment, serum cholesterol should be checked. Venlafaxin should be used with caution in patients with moderate to severe hepatic and renal impairment, and the dose should be adjusted accordingly. Venlafaxine should be used with caution in patients with a history of seizures. The drug should be discontinued in any patient who develops seizures, with an increase in seizure frequency. Patients with a history of bleeding disorders, hypomanic or manic episodes, glaucoma or at risk for angle-closure glaucoma should be closely monitored. If manifestations of allergic reactions, rash, urticaria related to Venlafaxine appear, the drug should be discontinued. Use caution when administering Venlafaxine to elderly patients. In addition, caution should be exercised with the possible risk of dizziness, unsteadiness due to orthostatic hypotension. Venlafaxine can occur symptoms of headache, dizziness, so it can reduce the ability to work. Therefore, patients should not drive or operate machinery. There have been reports of studies in rats showing weight loss and mortality in pups or death in the first 5 days of suckling. However, there are not enough data on pregnant women, so it should be used with caution, only used when absolutely necessary. Venlafaxine is excreted in breast milk and may be harmful to a nursing infant. Patients should discontinue use due to the risk of serious adverse effects in breastfed infants. A decision should be made whether to discontinue nursing or discontinue the drug. Venlafaxine 75mg medicine is commonly used in the brand name Venlafaxine Stada, belongs to the group of central nervous system drugs in the antidepressant drug subgroup. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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