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Yesom medicine 40mg is often used in the treatment of some cases such as peptic ulcer disease, gastroesophageal reflux disease, ... So how to use this drug effectively?
1. What is Yesom 40mg?
The drug is in the form of enteric coated tablets, the main ingredient in each tablet is Esomeprazole Magnesium dihydrate equivalent to Esomeprazole 40mg. Esomeprazole is an isomer of Omeprazole, used in the treatment of peptic ulcers, gastroesophageal reflux disease. This active ingredient has the effect of inhibiting the proton pump, preventing the secretion of acid into the stomach.
Yesom medicine 40mg is indicated in the following cases:
Zollinger-Ellison syndrome Peptic ulcer disease Severe gastroesophageal reflux disease Prevention and treatment of peptic ulcers caused by the use of non-steroidal anti-inflammatory drugs (NSAIDs). Yesom 40mg drug is contraindicated in the following cases:
People with hypersensitivity to the components of the drug or to Benzimidazole substitutes. People who are using Nelfinavir. Children under 18.
2. Dosage and how to use Yesom 40mg
How to use Yesom 40mg drug:
Yesom 40mg drug is reduced when taken with food, so it is necessary to take the medicine at least 1 hour before eating. Swallow the Yesom 40mg tablet whole, do not chew or crush it to increase bioavailability and prevent absorption in the stomach. The dosage of Yesom 40mg drug should be according to the doctor's prescription. The recommended dosage of Yesom 40mg drug is given to adults as follows:
Prophylaxis or treatment of peptic ulcers in NSAID users: Use a dose of 20mg/time/day for 4-8 weeks. Peptic ulcer with HP bacteria: Use dose 20mg/time, twice daily for 1 week or dose 40mg/time/day for 10 days in combination with Amoxicillin 1g and Clarithromycin 500mg twice/day for 7 days . Severe gastroesophageal reflux with esophagitis: The starting dose is 20-40mg / time for 4-8 weeks, can be taken for another 4-8 weeks if symptoms persist. Maintenance dose is 20mg / time / day, can be taken for 6 months. Gastroesophageal reflux disease has been cured: Use a dose of 20mg / time / day for 4 weeks, can be taken for another 4 weeks if needed. Zollinger-Ellison syndrome use Yesom medicine 40mg as prescribed by the doctor. People with severe liver failure: Use Yesom 40mg with a maximum dose of 20mg/day. Patients with mild and moderate hepatic impairment, renal failure and the elderly do not need to adjust the dose of Yesom 40mg. Yesom 40mg is not recommended for children because safety and efficacy have not been established. Minimizing missed dose, overdosage of Yesom 40mg drug affects the effectiveness of treatment. If you miss a dose of Yesom 40mg, take the replacement dose as soon as you remember. If you remember when it is almost time for your next dose, skip the missed dose. Do not take twice the usual dose to make up for the risk of a dangerous overdose.
When using an overdose of Yesom 40mg you may have symptoms such as confusion, lethargy, fast heartbeat, blurred vision, nausea, headache... At this point, you need to go to a medical facility immediately. nearest hospital for symptomatic and supportive treatment.
3. Side effects of Yesom 40mg
Possible side effects when taking Yesom 40mg with the corresponding frequencies are as follows:
Common side effects include: Headache, dizziness, dry mouth, abdominal pain, nausea, vomiting, fullness gas, constipation, diarrhea, skin rash. Less common side effects include: Fatigue, insomnia or somnolence, visual disturbances, itching, rash. Rare side effects include:
Photosensitivity, angioedema, urticaria, bronchospasm, anaphylaxis. Fever, sweating, peripheral edema. Agitation, depression, hallucinations, confusion. Agranulocytosis, leukopenia, thrombocytopenia. Jaundice, increased liver enzymes, hepatitis, liver failure. Taste disorder. Arthralgia, myalgia, interstitial nephritis. Dermatitis, bullous rash, epidermal necrolysis, Stevens-Johnson syndrome. Inform the doctor about the side effects encountered when using Yesom 40mg for timely handling.
4. Interaction of Yesom 40mg with other drugs
Do not combine Yesom 40mg with Atazanavir. If used concurrently, the dose of Atazanavir 400mg/time will need to be increased with Ritonavir 100mg and not more than 20mg of Esomeprazole. Yesom 40mg drug increases the risk of bleeding when used with Warfarin, which can even lead to death. Yesom 40mg also reduces the clearance of Diazepam, increasing the plasma concentration of Diazepam. Clarithromycin, Amoxicillin, Esomeprazole, when used concurrently, will increase plasma concentrations of Esomeprazole and 14-Hydroxy-clarithromycin.
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