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Tydol 500mg is a product indicated in many diseases with analgesic and antipyretic effects. The drug when entering the body is distributed in most tissues with a half-life of 1-3 hours. Depending on the condition and nature of the disease, the doctor will prescribe the appropriate dose.1. What does Tydol 500 do?
Tydol 500 is indicated for use in cases of high fever with the antipyretic effect of Acetaminophen. In addition, the drug is also used to treat symptoms of mild to moderate pain caused by causes such as: Headache, pain from flu and cold, sore throat, toothache, menstrual pain, pain due to bone inflammation joint.2. Pharmacodynamics of the drug Tydol 500 Acetaminophen is an effective pain reliever and fever reducer used as an alternative in some patients with contraindications to Aspirin. At the same dose, acetaminophen has the same pain-reducing and fever-reducing effects as aspirin. Acetaminophen has the advantage of helping to lower body temperature in people with fever, but it rarely lowers body temperature in normal people. In addition, at appropriate therapeutic doses, the drug has little effect on the respiratory and cardiovascular systems, does not change the acid-base balance, does not cause irritation, ulceration or gastric bleeding as when taking Aspirin and Salicylates .
When overdose of Acetaminophen with a high dose of more than 10g, it will damage the liver because the metabolite N-acetyl-p-benzoquinoneimin is toxic to the liver.
3. Pharmacokinetics of Tydol 500
Acetaminophen when entering the body will be rapidly absorbed by the gastrointestinal tract and 10-60 minutes after ingestion, peak plasma concentrations will be reached.The drug when entering the body is distributed in most tissues with a half-life of 1-3 hours. At usual therapeutic doses, plasma protein binding is insignificant but may increase as drug concentrations increase.
4. How to use the drug Tydol 500mg The drug Tydol 500 mg is administered orally in different doses depending on age. For adults and children 12 years of age and older, take 1-2 tablets per time and do not take more than 8 tablets per day. In case of need, it can be taken 4-6 hours apart each time.
Do not use Acetaminophen for pain relief for more than 10 days for adults and 5 days for children unless directed by your doctor. If the patient has a high fever above 39.5oC for more than 3 days and does not respond to antipyretic drugs, it is necessary to see a doctor for an examination.
The above dosage is for reference only and is not applicable to all cases. Depending on the condition and nature of the disease, the doctor will make appropriate instructions.
5. Some notes when using Tydol 500
When using the drug overdose, the patient may appear symptoms such as: Nausea, loss of appetite, vomiting, abdominal pain, paleness. On the other hand, administration of more than 10 g in adults and over 150 mg/kg body weight in children can cause partial necrosis of hepatocytes and progress to irreversible necrosis, metabolic acidosis and hepatic encephalopathy causing coma. enchantment or even death.
For emergency treatment of Acetaminophen overdose, early diagnosis is very important. Patients with severe toxicity should be treated aggressively with gastric lavage and preferably within 4 hours after oral administration with a sulfhydryl compound. Alternatively, N-acetylcysteine can be administered orally or intravenously for less than 10 hours after acetaminophen ingestion.
Tydol 500 mg is contraindicated for patients with a history of hypersensitivity to Acetaminophen, patients with heart disease, lung disease, kidney disease, anemia, impaired liver function, G6PD deficiency.
Some cases need to be used with caution, including:
Patients with severe liver or kidney failure; Patients with phenylketonuria - urine, heavy use of alcohol; The safety of Acetaminophen for pregnant women is unclear. Therefore, use Acetaminophen during pregnancy only in cases where it is absolutely necessary. In short, Tydol 500mg is a product indicated in many diseases with analgesic and antipyretic effects. Depending on the condition and nature of the disease, the doctor will make appropriate instructions. Therefore, you need to use the drug exactly as prescribed by your doctor to promote the effectiveness of treatment and ensure safety for health.
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