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Pizar 6 contains the main ingredient ivermectin. The drug is used to treat worm disease caused by the filariasis Onchocerca.
1. What is Pizar 6?
Pizar 6mg medicine is used in the treatment of worms with the main ingredient being ivermectin. In addition to treating Onchocerca filariasis, the drug is also effective in treating intestinal strongyloidiasis caused by Strongyloides stercoralis.
The drug is indicated in the treatment of Onchocerca filariasis and roundworms such as pinworms, strongyloides, hookworms, whipworms, roundworms. However, ivermectin has no effect on tapeworms or liver flukes. The effect of the drug is up to 12 months after taking it.
The drug has a direct effect on the neuromuscular system, causing the worms to be paralyzed and the larvae to be eliminated through the lymphatic system. Ivermectin does not cross the blood-brain barrier and is therefore unlikely to affect the human nervous system.
2. Pharmacodynamics
Ivermectin is a semi-synthetic substance of the avermectin group. This group is characterized by being isolated from the fermentation of Streptomyces avermitilis and having a large cyclic lactone structure. The spectrum of activity of this ingredient is wide on nematodes and worms of cattle, so it is also widely used in veterinary medicine.
Currently, ivermectin is the first choice drug for the treatment of filariasis Onchocerca volvulus with very strong larval killing effect but little effect on adult parasites. The larvae of filariasis in the skin disappear rapidly after taking the drug for 2 to 3 days, while the larvae in the cornea and anterior chamber of the eye are slower.
The drug lasts up to 12 months, so it is very useful in stopping the way the disease spreads. After one month of use, the larvae of the worms degenerate and die because the adult filariasis cannot escape.
3. How to use Pizar 6mg
Pizar 6 is administered orally. The effective time to take the drug is in the early morning when you have not eaten anything or another time. However, avoid eating within 2 hours before and after taking the medicine.
Dosage of the drug is determined for children over 5 years old and adults. The age of under 5 years old has not been determined to be safe.
Adults and children over 5 years old can take a single dose of 0.15mg/kg. Every year, the drug should be used at the same dose as above to prevent the return and be able to completely destroy the larvae of Onchocerca filariasis. For people with severe infection of the larvae in the eye, the reuse time can be shorter at about 6 months.
Dosage of ivermectin to treat Onchocerca infection is as follows:
| Cân nặng (kg) | Liều uống duy nhất |
| 15 - 25 | 3mg |
| 26 - 44 | 6mg |
| 45 - 64 | 9mg |
| 65 - 84 | 12mg |
| ≥ 85 | 0,15mg/kg |
4. Some notes when using Pizar 6mg
Pizar 6 has some contraindications for the following cases:
Patients with a history of hypersensitivity to ivermctin or any of its ingredients. The patient has a blood-brain barrier disorder such as meningitis or African Trypanosoma. Care should be taken when using the drug in the following cases:
Do not use the drug for children under 5 years old because there are no reports of safety in this age group. People with blood-brain barrier damage should be cautious because the drug increases GABA. When treating dermatitis caused by Onchocerca filariasis with ivermectin, more serious adverse reactions, especially edema and exacerbation of the disease, may occur. Above is the important information about Pizar 6, you need to pay attention to the use of the drug to achieve better results.
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Reference source: nhathuoclongchau.com
