What does Dogtapine treat?

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Dogtapine is a drug commonly used in the treatment of schizophrenia or behavioral disorders. The active ingredient of Dogtapine is Sulpirid 50mg. So the question is what does Dogtapine do?

1. What is Dogtapine?

Dogtapine is made in the form of 50mg capsules with the following ingredients:
The main active ingredient is Sulpirid 50mg; Excipients such as corn starch, magnesium stearate, corn starch.

2. What does Dogtapine do?

The ingredient Sulpiride in Dogtapine 50mg belongs to the group of psychotropic active ingredients of the benzamide group. This active ingredient has a selective inhibitory effect on Dopamine D2 receptors in the brain. Therefore, the drug Dogtapine offers antipsychotic effects and is indicated mainly for the treatment of schizophrenia.
Dogtapine when used in high doses has the ability to effectively treat schizophrenia with positive symptoms, while when used at low doses, it will be effective in treating schizophrenic patients with symptoms of depression Oh, not socializing.
Unlike other typical psychotropic drugs (such as Butyrophenon or Phenothiazine), the active ingredient Sulpiride in Dogtapine has the advantage of not causing emotional loss or drowsiness. In addition, some other characteristics of Sulpiride when compared with other schizophrenic drugs include: the drug does not act on the 5-HT/Noradrenalin sensitive Adenylcyclase system, does not cause postural symptoms, Does not affect GABA/Muscarin receptors and is not anticholinesterase.

3. What disease does Dogtapine treat?

Dogtapine 50mg is indicated in the following pathologies:
Chronic schizophrenia; Acute schizophrenia; Treatment of behavioral disorders; Short-term treatment of anxiety syndrome when other medications have not been effective.

4. Dosage of the drug Dogtapine

Dosage for children:
Children under 14 years old: Dogtapine is not recommended for this group of people; Children 14 years and older: Sulpiride dosage is 3-5 mg/kg per day. Dogtapine dosage for adults:
Treatment of negative symptoms in schizophrenia: Initial dose is 4 - 8 tablets/time, 2 times/day. Then gradually increase the dose to an effective therapeutic dose, up to 16 tablets/time, 2 times/day; Treatment of positive symptoms in schizophrenia: Initial dose of 8 tablets/time, 2 times/day. Then gradually increase until effective and maximum 24 tablets / time, 2 times / day; Treatment of combined negative and positive symptoms in schizophrenia: Use 8-12 tablets/time and 2 times/day. Dosage of the drug Dogtapine for the elderly: The initial oral dose is from 1-2 tablets / time, 2 times a day. Then gradually increase to an effective therapeutic dose, similar to that used in adults.
Dosage of Dogtapine in patients with impaired renal function: There should be a plan to adjust the dose or prolong the interval between doses depending on the creatinine clearance. Particularly, patients with moderate to severe renal impairment should not use Dogtapine 50mg when there are other alternative drugs.
Some notes on how to use Dogtapine 50mg:
Dogtapine is only made in the form of a round capsule, so it is indicated for oral use; When using, it is necessary to drink Dogtapine with a sufficient amount of water. Dogtapine can be used before or after meals. Although the symptoms of the disease improve or disappear, the patient must not stop taking the drug on his own, but must continue to take it for a full course of treatment.

5. Some contraindications of the drug Dogtapine

People with a history of allergy or hypersensitivity to the active ingredient Sulpiride or any other ingredient in the drug; Patients who are comatose, have neuroleptic drug poisoning, alcohol poisoning or diseases that cause central nervous system depression; People with acute porphyria or adrenal myeloma; Women who are pregnant, especially during the first 16 weeks of pregnancy because Dogtapine can cause adverse effects on the nerves of the fetus.

6. Side effects of the drug Dogtapine

Common undesirable effects:
Endocrine system: Menstrual disorders, amenorrhea, hyperprolactinemia, increased lactation; Nervous system: Insomnia, somnolence. Less common side effects:
Cardiovascular: QT interval prolongation; Nervous system: Parkinson's syndrome, extrapyramidal syndrome or excitability. Some rare side effects of the drug Dogtapine:
Tardive dyskinesia; Arrhythmia, bradycardia or orthostatic hypotension; Male gynecomastia syndrome. If the patient notices any unwanted effects during the use of Dogtapine, it is necessary to promptly notify the doctor and take timely intervention measures.

7. Dogtapine drug interactions

Concomitant use of Dogtapine 50mg with CNS depressants or antihypertensive drugs may lead to an increase in the effects of these drugs. Therefore, patients should be careful when using the two groups of drugs at the same time with Dogtapine 50mg; Dogtapine 50mg taken at the same time as lithium leads to an increased risk of extrapyramidal syndrome; Do not use the drug Dogtapine 50mg in combination with Levodopa because both occur competitive antagonism and thereby increase the sedative effect of the active ingredient Sulpiride.

8. Some notes when using and storing Dogtapine

Note and caution: When using Dogtapine 50mg for people with impaired renal function, it is necessary to adjust the dose and have a plan for close monitoring. In case of severe renal failure, the patient should be prescribed the drug in intervals.
The use of the drug Dogtapine 50mg should be closely monitored for the following cases:
Elderly people are at high risk of orthostatic hypotension; People with epilepsy because it can cause a decrease in the seizure threshold; People with mild mania taking the drug Dogtapine can make it worse; People who regularly drink alcohol or use products containing Ethanol because of the increased risk of drowsiness. In the process of using Dogtapine, if a high fever of unknown cause is found, the user should promptly stop the drug because this condition suggests neuroleptic malignant syndrome.
For women who are pregnant and breast-feeding: Women who are breastfeeding should not use or should stop taking Dogtapine because the active ingredient Sulpiride can be excreted in breast milk and harm the nursing infant.
Drivers and machine operators: Dogtapine 50mg drug has the effect of causing drowsiness, so it should not be used for driving vehicles or operating machinery.
Dogtapine 50mg should be stored in a cool, dry place, the room temperature is below 30 degrees Celsius and out of the reach of children.
Dogtapine is a drug commonly used in the treatment of schizophrenia or behavioral disorders. To be effective, patients need to take the drug according to the prescription and consult a doctor or pharmacist.
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