What diseases does the Synflorix pneumococcal vaccine prevent?

This is an automatically translated article.

The article is professionally consulted by Master, Doctor Nguyen Hai Ha - Pediatric Center - Vinmec Times City International Hospital
Pneumococcal infections can range from serious life-threatening illnesses such as meningitis, pneumonia, and sepsis to less serious but much more frequent illnesses such as sinusitis or otitis media. Therefore, vaccination against pneumococcal disease is considered an effective preventive measure.
Previously, in Vietnam, there was only the French pneumococcal vaccine, Pneumo 23, which is a polysaccharide shell of bacteria, so the time to vaccinate was later (after 2 years of age). Currently, we have Synflorix vaccine which is a conjugate vaccine of bacterial polysaccharide envelope and protein D of Hemophilus Influenza unspecified type. This vaccine is indicated earlier, possibly between 6 weeks and 5 years of age.

1. What is pneumococcal disease?

Pneumococcal disease is the term used to describe a number of infections caused by the bacteria Streptococcus pneumoniae, and it is estimated that nearly half a million children die each year worldwide from pneumococcal disease. Therefore, early childhood vaccination will help reduce the harmful effects of pneumococcal diseases.
Pneumococcal (Streptococcus pneumoniae) infection can cause serious life-threatening illnesses such as meningitis (inflammation of the membrane surrounding the brain), pneumonia (a respiratory infection) and sepsis (with bacteria present). abnormality in the blood) to less serious diseases with a much higher incidence such as sinusitis or otitis media, so vaccination against pneumococcal disease is considered a proactive, economical and effective measure. important role in the prevention of these diseases.

2. What vaccines are used to prevent pneumococcal disease?

Synflorix pneumococcal vaccine is a pneumococcal vaccine containing the 10 most common antigens of Streptococcus pneumoniae bacteria including 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F , 23F. The vaccine will stimulate the body's immune response to produce antibodies against the above types of pneumococcus, so when the pneumococcus enters the body, it will be protected by the antibodies produced by the vaccine, not causing any damage. disease for the body.


When the body is exposed to foreign organisms, such as bacteria and viruses, the immune system creates antibodies against them. Antibodies help the body recognize and destroy foreign organisms. They then remain in the body to help protect against infections caused by the foreign organism itself. This is called active immunity. The body's immune system makes different antibodies for each foreign organism it encounters. Therefore, vaccine-induced immunity is specific active immunity, when vaccinated against any disease, the body will produce antibodies against the bacteria and viruses that cause that disease.
Synflorix contains 10 common pathogenic pneumococcal serotypes. The vaccine will stimulate the immune system to create antibodies against pneumococcal bacteria when the bacteria actually enter the body, thereby protecting the body from pneumonia, meningitis, ear infections. In between, bacteremia caused by these types of pneumococci.
Synflorix pneumococcal vaccine is used for babies 6 weeks - 5 years old. The injection regimen depends on the age at which your child starts his or her first Synflorix injection. However, getting the vaccine as early in the age as possible is recommended because it helps the child's body to form antibodies to protect the body when pneumococcal enters the body. Synflorix vaccine is administered intramuscularly and the appropriate site is the anterolateral aspect of the thigh in young children or the brachial deltoid muscle in older children.

The Synflorix vaccine is generally safe. However, some common side effects may still occur after the injection. Common side effects when injecting Synflorix vaccine are loss of appetite, pain, redness, swelling at the injection site; There may be stiffness at the injection site and fever. Side effects are usually transient and go away in 1-2 days. For very rare manifestations such as unusual fussiness, diarrhea, vomiting, rash, hematoma at the injection site, high fever ≥ 390 C, no improvement in antipyretic drugs or other signs (erythema on the skin) , rapid breathing, difficulty breathing, cyanosis, poor feeding, aborting, convulsions, lethargy...) then parents need to take the child to the nearest medical center for timely intervention.

3. Where to get Synflorix vaccine against pneumococcal?

Vinmec International General Hospital provides the Synflorix vaccination service produced by GlaxoSmithKline (GSK) - Belgium.
The advantages of vaccination at Vinmec include:
Children will be examined by specialist doctors, fully screened for physical and health problems, and advised on vaccines and injection regimens. , possible reactions, how to monitor and care for children after vaccination before giving the indication for vaccination to ensure the best effectiveness and safety for the child. A team of experienced and professional pediatric doctors and nurses, understand children's psychology and apply effective pain relief methods for children during the vaccination process. 100% of vaccinated children were monitored for 30 minutes after vaccination and reassessed before leaving. Post-vaccination monitoring room is fully equipped with emergency facilities; the team of doctors - nurses are trained in anaphylaxis emergency management to ensure timely and correct treatment when an incident occurs. In addition, Vinmec Hospital system always has an emergency team ready to coordinate with the vaccination room to handle cases of anaphylaxis, respiratory failure - circulatory arrest to ensure the safest vaccination for children. . The vaccination room is airy, with a play area, helping children feel comfortable as if they are walking and have a good mentality before and after vaccination.

Vinmec International General Hospital is currently providing a Package Immunization Program with a variety of vaccines for different audiences, from infants, young children, adults, and women before and during pregnancy pregnant. Particularly in December 2019, Vinmec will give you free newborn Hepatitis B Vaccine (immunization immediately after birth) when you sign up for a Package Immunization Package for children aged 0-1 or 0-2 years old. .

Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.

Source: According to the information approved by the Drug Administration.