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Oral Agichymo is used to treat edema after trauma, surgery. Let's learn the information in the following article to understand more about Agichymo drug.
1. What is Agichymo?
Agichymo drug has the main active ingredient is Chymotrypsin (alpha chymotrypsin) and a sufficient amount of excipients including: Lactose, Disodium starch glycolate, Magnesium stearate, Microcrystalline cellulose. Chymotrypsin is an enzyme that breaks down proteins - enzymes are substances used to speed up certain chemical reactions in the body. Chymotrypsin contributes to the breakdown of fibrin fibers that are formed during inflammation. Chymotrypsin is also a substance produced by the body in the pancreas, so it is relatively safe to use in most cases. However, it can also be taken externally to improve another health condition or medical condition. Chymotrypsin breaks down proteins into amino acids, especially cutting chains of aromatic amino acids such as tyrosin, tryptophan, methionine, norleucin, phenylalamin and norvalin. This mechanism of Chymotrypsin has helped to dissolve the vitreous suspension fibers without seriously affecting other structures of the eye. Therefore, they have been used in the treatment of intracapsular cataract removal in patients aged 20 to 60 years. However, there are some risks associated with this method and more advanced methods have been developed for this procedure. Therefore, today, people do not use this method to surgically remove cataracts anymore. Chymotrypsin is also used to treat edema after surgery or trauma, in addition to other enzymes involved in the prevention of tissue damage during inflammation and fibrin formation.
2. What disease does Agichymo treat?
2.1. Indications for Burns: There is some evidence that taking a mixture of chymotrypsin and trypsin orally can reduce tissue destruction in burn patients. Chronic pain and swelling (inflammation) of the salivary glands (chronic obstructive parotid gland inflammation). There is some evidence that injecting chymotrypsin into the channels (ducts) in the salivary (parotid) glands can reduce pain and swelling in people with chronic obstructive parotiditis. Fractures: There is some evidence that taking a mixture of chymotrypsin and trypsin by mouth can reduce swelling in hand fractures. Asthma . Bronchitis . Sinus infection. Abscess or sores on the skin Heals the wound. Relieve pain, reduce edema after injury or after surgery. Used in cataract surgery (currently not applied) More evidence on the above effects of Chymotrypsin is needed, so the use of Agichymo should be under the guidance of a physician.
2.2. Drug interactions Alphachymotrypsin is often used in combination with other enzyme drugs to increase the effectiveness of treatment. In addition, a balanced diet or the use of vitamins and mineral salts are recommended to increase alphachymotrypsin activity. Some seeds such as jojoba beans (in the US), wild soybeans Tomato, a variety of proteins inhibit alphachymotrypsin activity. These proteins can be inactivated by boiling. Alphachymotrypsin should not be used with acetylcysteine, a medicine used to dissolve phlegm in the lungs. Alphachymotrypsin should not be combined with anticoagulants (blood thinners) as they increase their effectiveness.
3. How to use Agichymo effectively?
The drug is available in powder form for injection or in tablet form for oral administration, sublingually.
Dosage for oral: 2 tablets / day, from 3 to 4 times / day. Dosage for lozenges: take from 4 to 6 tablets / day at different times. Note that the drug must be gradually dissolved under the tongue. However, the dose depends on many other factors such as the user's age, health, and several other conditions. Follow the directions on the product label and your doctor's instructions.
4. Be careful when using Alphachymotrypsin
Alphachymotrypsin was generally well tolerated and did not cause significant side effects. Patients who should not be treated with enzymes include Patients with inherited and non-hereditary clotting disorders Those who have recently undergone or are about to undergo surgery Patients on anticoagulant therapy People are allergic to proteins Pregnant or breastfeeding women Patients with peptic ulcers. Used in cataract surgery in patients under 20 years of age. People with increased vitreous pressure People with congenital cataracts or open wounds in the eye.
5. Undesirable side effects of the drug Alphachymotrypsin
During the use of Alphachymotrypsin, the patient may experience allergic reactions - very rarely: itching, difficulty breathing, swelling of the lips or throat, fainting.
To use the drug safely, you should list the history of allergies to any of the ingredients of the drug with your doctor before treatment. Make sure you are not pregnant before taking the pill and if using it for a long time consider your plans to get pregnant. In addition, this drug may interact with anticoagulants causing side effects. Therefore, if you are taking anticoagulants, tell your doctor.
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