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For millions of women who are having trouble conceiving, fertility drugs are the first step in treatment, they promote ovulation. Depending on the cause of infertility, women can take a number of drugs to overcome this condition.
1. Popular fertility drugs for infertile women
Every month, follicle stimulating hormone in the female pituitary gland will be secreted. As a result, one follicle of the ovary matures gradually until one or two follicles reach maturity. At that time, in order for the largest and most "ripe" follicle to burst, releasing the ovule (usually called an egg), the pituitary gland secretes the hormone LH. The egg will move into the fallopian tube. In order to conceive, the sperm must fuse with the egg here. Ovulation disorders, including menstrual irregularities or amenorrhea due to deficiency or imbalance in hormones are the cause of infertility in women. Today, many fertility drugs have successfully treated these cases.
Fertility drugs for women that often stimulate ovulation by simulating the effects of natural FSH and LH include:
Clomiphene works by stimulating hormones in your brain, stimulating a (or several) eggs develop and are released from your ovaries. The drug blocks the effects of the hormone estrogen in order to trick the body into increasing levels of two hormones needed for ovulation. These two hormones are: Follicle Stimulating Hormone (FSH) and Luteinising Hormone (LH). FSH makes the eggs mature and ready to be released. LH triggers the release of one or more mature eggs, which, after ovulation, travel down the fallopian tubes ready to be fertilized by sperm. Usually, clomiphene is taken as a pill for the first 5 days of your cycle and for up to 6 months.
Rối loạn phóng noãn là một trong những nguyên nhân gây hiếm muộn ở phụ nữ
Gonadotropins stimulate your ovaries directly to produce (or several) eggs. Luteinising hormone (LH) and follicle-stimulating hormone (FSH) are the hormones that gonadotropins act on. FSH and LH directly stimulate the ovaries to produce and ripen eggs. Gonadotropins are often used for women with PCOS who have not responded to other medications or for women who are using in vitro fertilization (IVF). FSH and LH injections can be given over 10 to 12 days. This causes the ovaries to begin to develop and mature the follicles.
Your doctor will give you a gonadotropin injection after the last shot of another hormone called human chorionic gonadotropin (hCG).
HCG will make the newly developed eggs ripen quickly. Ripe eggs will be released from the body or separated from the ovaries with a minor procedure if the mother is using IVF.
Lh stimulates follicles to release eggs. HCG ensures that the follicles are in the most suitable condition for ovulation and the production of progesterone needed to sustain a pregnancy.
Some women need to combine these drugs with intrauterine insemination (IUI) or assisted reproductive technology (ART), such as in vitro fertilization (IVF). People who are undergoing IVF can also take other fertility drugs to help form the lining of the uterus during pregnancy and prevent the ovaries from releasing an egg prematurely.
2. Reproductive drugs promote different effectiveness depending on each subject
This depends on the body and cause of the woman having difficulty getting pregnant. For example, women with polycystic ovary syndrome (PCOS) usually respond well to clomiphene, but women without PCOS must take the prescription drug Metformin to help with ovulation.
Thuốc hỗ trợ sinh sản phát huy hiệu quả khác nhau tùy vào từng đối tượng
3. Risks of using fertility drugs
Many of these drugs have been used safely and successfully for over 40 years. But like other fertility treatments, these drugs can double your chances of conceiving — and women carrying multiples are at greater risk of complications, including miscarriage and preterm labor. . About 10% of women taking clomiphene have multiple pregnancies (mostly twins), and about 30% of women taking gonadotropins have multiples (mostly twins).
Besides, like other drugs besides the main effect, both Clomiphene and Gonadotropin drugs have some unwanted side effects that may occur.
Most women respond well to Clomiphene. But in some cases, there may be some side effects such as:
Restless mood, hot flushes Thick and dry cervical mucus Pelvic pain Light breast, Ovarian cyst Nausea, headache Deep Mild sensitivity Blurred or double vision (this is less common).
Sử dụng thuốc có thể xảy ra một số tác dụng phụ không mong muốn
Some unwanted effects may be encountered when using Gonadotropin drugs such as:
Severe pelvic pain Swelling of the legs and arms Abdominal pain, diarrhea, difficulty breathing Nausea or vomiting Urinating less than usual Headache , feeling restless or irritable Mild swelling, pain or swelling of the breast Weight gain, depression Pain, swelling or irritation at the injection site Customers can come to the Fertility Center - Vinmec International General Hospital . This is the leading center in Vietnam, which has developed and applied a comprehensive medical examination and treatment process, combining both gynecology and obstetrics and gynecology to provide the optimal method for each patient's case.
Advantages when customers choose Vinmec fertility center:
Equipped with modern equipment, clean air system according to international standards to ensure lab quality, single cabinet system to optimize quality embryo, improving the success rate for each cycle of artificial insemination. Implement most advanced assisted reproductive techniques in the world: ICSI (injection of sperm into the oocyte cytoplasm); support embryo escape membrane; Reproductive reserve: embryo freezing, sperm freezing, oocyte freezing to help customers take the initiative in giving birth at will, transferring embryos on day 5, minimizing pregnancy; male infertility techniques (PESA, MESA, TEFNA, TESE) Besides advanced reproductive support methods, a team of excellent doctors in the country and the world, with prestige and long-term experience in the field of infertility .
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
Reference source: babycenter.com
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