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Xitoran belongs to the group of antibiotics, used in the treatment of urinary tract infections, nephritis, and upper respiratory tract infections. Before using Xitoran, you should consult a pharmacist or specialist. Here are some information to help you better understand what Xitoran does?1. What is Xitoran?
Xitoran belongs to the group of antibiotics, drugs that are effective in the treatment of urinary tract infections, respiratory tract, skin and soft tissue infections, arthritis.
Prepared in capsule form, Xitoran drug has the active ingredient Cefadroxil 500mg in each tablet. The main active ingredient Cefadroxil of Xitoran belongs to the first generation Cephalosporin antibiotic group. The first generation Cephalosporin antibiotics have been evaluated for their antibacterial effects by inhibiting bacterial cell wall synthesis, preventing bacteria from dividing and multiplying in numbers.
According to in vitro tests, Xitoran has antibacterial spectrum on many Gram-positive and Gram-negative strains.
Gram-positive bacteria sensitive to Xitoran include: penicillinase-producing and non-penicillinase-secreting Staphylococcus, beta-hemolytic Streptococcus strains, Streptococcus pyogenes and Streptococcus pneumoniae. Gram-negative bacteria sensitive to Xitoran include: Kleb-siella pneumoniae, Escherichia coli, Moraxella catarrhalis.
2. Uses of the drug Xitoran
With a relatively limited antibacterial spectrum, Xitoran antibiotic has the effect of inhibiting the growth and killing of bacteria in mild and moderate infections. In infections caused by Gram-positive bacteria, penicillin is still preferred over 1st generation Cephalosporins.
3. Pharmacokinetics of Xitoran
With active ingredient Cefadroxil well absorbed in the gastrointestinal tract and not affected by food, bioavailability, Xitoran is made in capsule form for patients to use orally. A dose of 500 mg of Cefadroxil in each Xitoran tablet will result in peak plasma concentrations of 30 micrograms/ml 1 hour 30 minutes to 2 hours after oral administration. Compared with Cefalexin, Xitoran has a longer lasting plasma concentration of Cefadroxil. There is 20% of Cefadroxil bound to plasma proteins, the half-life of the drug in plasma in normal people is 1 hour 30 minutes and in people with renal failure is 14 - 20 hours.According to specific studies, Xitoran is evenly distributed in tissues and fluids throughout the body, the drug can cross the placenta and is excreted in breast milk.
The metabolism of Xitoran in the body is not much, so up to 90% of the drug is excreted in the urine as unchanged drug within 1 day through glomerular filtration and tubular secretion.
4. Indications for taking the drug Xitoran
Xitoran with active ingredient Cefadroxil 500mg is used in the treatment of mild and moderate bacterial infections, specifically as follows:
Urinary tract infections: Nephritis - pyelonephritis, cystitis, gynecological infections, childbirth sex, urethritis. Respiratory infections: Pharyngitis, tonsillitis, acute - chronic bronchitis, lung abscess, laryngitis, sinusitis, empyema, otitis media. Lymphadenopathy, skin abscess, ulceration in patients lying for a long time immobile, erysipelas, mastitis. Osteomyelitis, inflammatory arthritis.
5. Contraindications to taking Xitoran
According to the records of contraindications of Xitoran to the present time, the drug is not used for cases with a history of hypersensitivity to the Cephalosporin antibiotic group.
6. Dosage and how to use Xitoran
How to use: Xitoran is made in capsule form, so users only need to take Xitoran with a full glass of water.
Dosage of Xitoran:
Adults: 500mg-1g/dose, 1 or 2 times a day depending on the severity of the infection; Children from 1-6 years old: 250mg/time, 2 times a day; Children over 6 years old: 500mg/time, twice a day.
7. Side effects of the drug Xitoran
Xitoran is used in the treatment of mild to moderate infections, so the side effects of this antibiotic are also assessed as mild, including:
Headache; Nausea, vomiting; Mild gastrointestinal upset, diarrhea. The side effects of Xitoran are also easy to treat if they are encountered while taking the drug. Patients should discuss with their doctor, do not stop taking the drug on their own if they experience the above side effects.
8. Notes when using the drug Xitoran
Care should be taken when using Xitoran in patients with a history of allergy, hypersensitivity to Cephalosporins and penicillins In patients with renal failure, gastrointestinal diseases (stomach pain, digestive disorders, etc.). .) requires careful monitoring as side effects may be more severe when used in these subjects. In the case of long-term use of Cefadroxil, it is necessary to monitor for signs of infection because it is possible to develop non-susceptible strains of bacteria causing superinfection. If there is a case of superinfection, must stop using the drug and notify the specialist. Xitoran is an antibiotic belonging to the first generation Cephalosporin group. Xitoran is effective in the treatment of mild and moderate bacterial infections, prescribed by a doctor, patients do not arbitrarily take the drug and change the dose under any circumstances. any form.
