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Vitamin PP 50 is a water-soluble B group vitamin that plays an important biochemical role in cellular metabolism. Vitamin PP is abundant in liver, kidney, fish meat, yeast, cereals and green vegetables. In the body, intestinal microorganisms synthesize small amounts of vitamin PP.1. What are the uses of Vitamin PP 50?
Vitamin PP 50 is prepared in the form of tablets with the main ingredient is Nicotinamide (vitamin PP) 50mg.
In the body, nicotinamide is converted to nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). NAD and NADP act as coenzymes essential for cellular respiration, glycogenolysis, and lipid metabolism.
These two types of coenzymes participate in the transport of hydrogen and electrons in redox reactions. Therefore, it plays an important role in the metabolism of fatty acids, cholesterol and creates ATP energy for the cellular respiratory chain.
When taking high doses of vitamin PP has the effect of reducing LDL and increasing HDL, causing peripheral vasodilation.
Vitamin PP deficiency will cause symptoms such as:
Anorexia; Attenuate ; Jittery; Glossitis; Stomatitis; Dermatitis, especially inflammation of the skin in open areas such as the face, feet, hands. Severe vitamin PP deficiency will cause typical symptoms that are dermatitis, diarrhea and neurological and mental disorders.
The effect of Vitamin PP 50 is evident in the following cases:
Prevention of nicotinamide deficiency; Prevention and treatment of pellagra with manifestations such as: Skin lesions, especially in places exposed to sunlight. Glossitis, stomatitis. Dyslipidemia - blood . Vitamin PP 50 is contraindicated in the following cases:
People who are allergic to nicotinamide; Severe liver disease; Gastric ulcers; Arterial hemorrhage; Severe hypotension. Caution should be exercised when used in patients with a history of:
Stomach ulcer; Diabetes mellitus; Gout ; Liver failure.
2. Dosage and usage of Vitamin PP 50
Vitamin PP 50 is used orally. Dosage should follow the doctor's instructions, the reference dose is as follows:
Adults: Use dose 1 - 2 tablets/time, 3 times a day; Children over 5 years: Use half the adult dose. When an overdose of Vitamin PP 50 occurs, there is no specific antidote. It is necessary to use measures to induce vomiting, gastric lavage, treatment of acquired symptoms and supportive treatment.
3. Side effects of Vitamin PP 50
Small doses of Vitamin PP 50 are not usually toxic. However, using high doses of Vitamin PP 50 may occur some of the following side effects:
Common side effects of Vitamin PP 50 include:
Nausea; Facial flushing; Itching and burning sensation in the skin. Less common side effects of Vitamin PP 50 include:
Progressive gastric ulcer; Vomit; Anorexia ; Flatulence; Diarrhea; Dry skin; Hyperpigmentation; Jaundice; Liver failure; Reduced glucose tolerance; Increased secretion of sebaceous glands; Make gout worse; Increased blood sugar; Hyperuricemia ; Headache; Blurred vision; Lower blood pressure; Dizzy ; heart palpitations; Faint. Very rare side effects of Vitamin PP 50 include:
Anxiety; Alarm; Urinary glucose ; Abnormal liver function; Abnormal prothrombin time; Hypoalbuminemia; Anaphylaxis. If you experience any side effects of Vitamin PP 50, inform your doctor or go to a medical facility for timely assistance.
4. Interaction of Vitamin PP 50 with other drugs
Taking Vitamin PP 50 with HMG-CoA reductase inhibitors may increase the risk of rhabdomyolysis; Taking Vitamin PP 50 together with alpha-adrenergic blockers may cause excessive hypotension; Diet and/or dosage of oral hypoglycemic agents or insulin may need to be adjusted when used concomitantly with Vitamin PP 50; Taking Vitamin PP 50 together with hepatotoxic drugs may lead to increased hepatotoxicity; Vitamin PP 50 should not be used concomitantly with carbamazepine because it will increase plasma carbamazepine concentrations leading to increased toxicity. The above is information about Vitamin PP 50. Patients need to carefully read the instructions for use, strictly follow the indications and doses, and consult a doctor to achieve the best treatment effect.
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