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Verapime is a broad-spectrum antibacterial antibiotic whose main ingredient is Cefepime, belonging to the antibiotic group. Fourth generation cephalosporin, strong bactericidal effect on both gram-negative and gram-positive bacteria. However, this is a prescription drug, so patients need to use it exactly as directed by a doctor or pharmacist.
1. What is Verapime?
Verapime drug is a broad-spectrum antibiotic, Betalactam family, belonging to the IV generation Cephalosporin group. The drug has the main ingredient Cefepime 1g vial or 2g vial, prepared in the form of Cefepime hydrochloride monohydrate, which is a powder for injection with a solvent for injection. The drug is prescribed by a doctor, you should not self-use without consulting a qualified doctor.
2. Uses - What is the indication for Verapime?
Verapime has antibacterial activity that is sensitive to strains of bacteria such as: Salmonella, Shigella, Escherichia coli, Streptococcus pneumonia, enterobacter, Clostridium perfringens,...
Verapime is indicated in the following cases: lower respiratory tract: pneumonia,... Urinary tract infection: urinary tract infection,... Abdominal infection: peritonitis, cholangitis,... Septicemia Gynecological infection Meningitis caused by bacteria
3. Usage and dosage of Verapime
How to use:
Verapime is prepared in the form of a powder for injection with solvent for injection.
Route of administration: Slow intravenous injection or deep intramuscular injection. Use the solvent for injection that has been mixed into the vial of Verapime, then shake well to completely dissolve the drug to create a homogeneous solvent.
Note: Mix immediately before injection to avoid infection.
Dosage:
The recommended dose of the drug is based on the patient's weight, age, and infection status as follows:
For adults and children weighing over 40kg
Urinary tract infection severity mild and moderate: dose from 0.5 to 1g/12 hours/time x 02 times/day. Intravenous or deep intramuscular injection. In case of other mild and moderate infections, excluding urinary tract infections: dose of 01 g / 12 hours / time x 2 times / day. Intravenous or deep intramuscular injection. Severe infections: dose of 02 g / 12 hours / time x 02 times / day. Intravenous injection. Very serious infections: dose of 02 g/ 08 hours/time x 03 times/day. Intravenous injection. Note: The duration of Verapime antibiotic treatment is usually 7-10 days depending on the patient's infection status, more severe infections may be indicated for longer duration of treatment. Example: Fever due to leukopenia, the duration of treatment is not less than 7 days. For children over 2 months old and patients weighing less than 40kg
Cases of pneumonia, urinary tract infections, skin - soft tissue infections: Dosage is based on weight, 50mg/kg/day every 12 hours. 12 hours/time x 02 times/day, treatment time 7-10 days. In case of severe infection, the interval between doses is 8 hours/time. Intravenous injection Sepsis, meningitis, fever due to leukopenia: dose 50mg/kg/ 8 hours x 03 times/day, duration of treatment for 7-10 days. Note: Verapime is not recommended for children under 2 months of age because there are not many studies on this subject. In special cases, it can be used with a reference dose of 30mg/kg/12 hours, intravenously. You need to consult with a qualified doctor for the most accurate advice.
4. In which cases is Verapime not used?
Contraindications of Verapime drug in the following cases:
The patient is hypersensitive to one or any of the ingredients of the drug. Patient has anaphylaxis to penicillin. Should not be used in patients with severe renal impairment. Not for use by pregnant women, lactating women and children under 2 months of age.
5. What are the side effects of Verapime?
When taking Verapime you may experience the following side effects:
Digestive disorders: vomiting, nausea, diarrhea, abdominal pain. Skin: rash, rash, itching, urticaria. Fever, headache. Anaphylaxis, leukopenia are rare. If you experience any unwanted side effects, immediately notify your doctor or health care professional for timely treatment.
6. Verapime drug interactions
Currently, there have not been many studies on drug interactions of Verapime (Cefepime) with other drugs or foods. Therefore, to ensure patient safety, you should inform your doctor about your medical history, allergy history, drugs you are using, herbs, functional foods, ..... so that the doctor can make appropriate considerations in treatment. However, it should not be mixed with other drugs in the same syringe or infusion to avoid side effects.
7. What to do when overdose or forget dose of Verapime?
When overdose, there is a risk of kidney toxicity, because the drug is excreted by the kidneys, so that kidney function will be affected. In this case, hemodialysis or peritoneal dialysis may be used to assist in removing Verapime from the blood.
When you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. You need to consult a professional doctor to get the best remedy.
8. What are the precautions when using Verapime?
For elderly patients, caution should be exercised when taking the drug: Clinical studies have shown that, because the drug is mainly excreted by the kidneys, the kidney function of the elderly often declines with age, so when using the drug for patients This condition requires control of renal function, creatinine clearance.
For patients with a history of asthma, allergies: You need to notify your doctor for close monitoring and appropriate medication adjustment.
In the injection process must be performed by medical staff, must ensure the correct aseptic procedure.
Do not mix with other drugs in the same syringe and infusion to avoid possible disadvantages.
In short, the drug Verapime has the main active ingredient Cefepime. This is a broad-spectrum antibiotic, bactericidal, treating infections caused by gram-negative and gram-positive bacteria. However, this is a prescription drug, so patients need to take it exactly as directed by a doctor or pharmacist.
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