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Vacoacilis 20 is a prescription medicine with the main ingredient Tadalafil, used in the treatment of erectile dysfunction in men. To ensure effective use, users need to strictly follow the instructions of the doctor or pharmacist.1. Uses of Vacoacilis 20
Vacoacilis 20 is made in the form of film coated tablets with the main ingredient in each tablet is Tadalafil 20mg.
Penile erection in men is due to increased blood volume here from dilation of penile arteries and cavernous smooth muscle. This response is mediated by the release of nitric oxide at the nerve terminals and epithelial cells, which stimulates increased synthesis of cyclic GMP in smooth muscle cells. Ring GMP has the effect of relaxing smooth muscle and increasing blood flow to the corpus cavernosum, thereby making the penis erect. Tadalafil has the effect of inhibiting phosphodiesterase type 5 (PDE5), thereby increasing the amount of cyclic GMP, so it helps to improve erection in men. However, sexual stimulation is still required during use to initiate the release of nitric oxide, so tadalafil is ineffective in the absence of sexual stimulation.
2. Indications and contraindications for the use of Vacoacilis 20
Vacoacilis 20 is indicated for erectile dysfunction in men.
Vacoacilis 20 is contraindicated in the following cases:
Vacoacilis 20 should not be used concurrently with any organic nitrate compounds. Patients with hypersensitivity to any ingredient of the drug. Precautions when using Vacoacilis 20:
People with cardiovascular disease: Doctors need to consider the patient's cardiovascular status carefully before using Vacoacilis 20. Patients with congenital retinopathy. Patients including retinitis pigmentosa should not use Vacoacilis 20. If you experience penile pain continuously for more than 4 hours, you need to tell your doctor. The safety and effectiveness of the combination of Vacoacilis 20 and other erectile dysfunction drugs have not been evaluated. Keep Vacoacilis 20 out of the reach of children.
3. Dosage and how to use Vacoacilis 20
Vacoacilis 20 is used orally, you should take the drug with a sufficient amount of water, take the drug before sexual activity.
Dosage of Vacoacilis 20 should be according to the prescription of a specialist. The recommended dose is as follows:
The usual starting dose is 10 mg. The dose can be increased to 20 mg or decreased to 5 mg depending on the tolerability and effectiveness of the drug for each person. The maximum dose of Vacoacilis 20 is once a day. The active ingredient Tadalafil in Vacoacilis 20 is effective up to 36 hours after taking the drug. Therefore, you should consider to use the right dose of the drug. Renal Impairment: No dose adjustment of Vacoacilis 20 is necessary in patients with mild renal impairment. Patients with moderate renal impairment should be started at 5 mg, with a maximum dose of 10 mg every 48 hours. Patients with severe renal impairment use a maximum dose of 5 mg. Hepatic impairment: In patients with mild and moderate hepatic impairment, Vacoacilis 20 should not be used more than 10mg/day. Patients with severe liver failure should not use Vacoacilis 20. For healthy people, tadalafil can be used in single doses up to 500mg. Accordingly, using multiple doses of 100mg, the rate of unwanted effects is still similar to that of low doses.
In case you overdose on Vacoacilis 20, appropriate symptomatic and supportive measures should be applied. Please notify your doctor immediately for advice and treatment as soon as possible, to avoid side effects.
4. Side effects of Vacoacilis 20
In the process of using Vacoacilis 20, you may experience some side effects, including:
Headache Digestive disorders Back pain Muscle pain Nasal congestion Flushing face Hand leg pain Angina pectoris Low blood pressure Myocardial infarction Tachycardia Palpitations. If you experience any side effects while using Vacoacilis 20, please inform your doctor, or immediately go to the nearest medical facility for timely treatment.
5. Interaction of Vacoacilis 20 with other drugs
Co-administration of Vacoacilis 20 with cytochrome P450 inhibitors (eg, ketoconazole, erythromycin, ritonavir, itraconazole) increases tadalafil exposure. Co-administration of Vacoacilis 20 with cytochrome P450 inducers (eg, rifampin, phenytoin, carbamazepine, phenobarbital) reduces tadalafil exposure. To avoid drug interactions, tell your doctor about the drugs, herbs and supplements you are taking. Vacoacilis 20 is a prescription medicine with the main ingredient Tadalafil, used in the treatment of erectile dysfunction in men. To ensure effective use, users need to strictly follow the instructions of the doctor or pharmacist.
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