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Tyracan 100 is a prescription medicine used to treat certain cancers. So what does Tyracan 100 do and how does it work?1. Uses of Tyracan 100
Tyracan 100 is formulated as a film-coated tablet with the main ingredient in each tablet being Erlotinib 100mg. Erlotinib binds to epidermal growth factor receptors, thereby inhibiting the intracellular phosphorylation of tyrosine kinase. This active ingredient is used for the local control of advanced or metastatic non-small cell lung cancer that has not responded to other treatments. Erlotinib is also used in combination with gemcitabine for the first-line treatment of patients with locally advanced, or metastatic, pancreatic cancer who cannot undergo surgical resection.In nonclinical experimental models, inhibition of EGFR (epidermal growth factor receptor) phosphotyrosine has been shown to inhibit and/or induce cell death.
Tyracan 100 is indicated in the following cases:
Advanced or metastatic non-small cell lung cancer in situ after failure of at least one prior chemotherapy regimen. Tyracan 100 in combination with gemcitabine for the first-line treatment of patients with locally advanced, unresectable, or metastatic pancreatic cancer. Tyracan 100 is contraindicated in the following cases:
People with hypersensitivity to erlotinib or to any of its ingredients.
2. Dosage and how to use Tyracan 100
How to use Tyracan 100 drug as follows:The drug is used orally, taking the tablet with a sufficient amount of water. Take the drug at least 1 hour before or 2 hours after eating.. Dosage of Tyracan 100 should be according to the prescription of a specialist, the reference dose is as follows:
Standard dose of Tyracan 100: Non-small cell lung cancer: Use 150mg/day. Pancreatic cancer: Use a dose of 100mg/day, in combination with gemcitabine. Special Tyracan 100 Dosage Instructions: Dosage adjustment of Tyracan 100 may be necessary when co-administered with substrates and regulators of the CYP3A4 system. Hepatic impairment: Dosage reduction or discontinuation of Tyracan 100 should be considered if severe adverse reactions occur. Renal impairment and use in children: The safety and efficacy of Tyracan 100 have not been studied in these patient populations. Smokers: Smoking can reduce the distribution of erlotinib by 50-60%. The maximum dose of Tyracan is 300mg/day. Do not exceed the prescribed dose of Tyracan 100. When you have unusual symptoms due to an overdose of Tyracan 100, you need to immediately contact your doctor or go to the nearest medical facility for timely treatment.
3. Side effects of Tyracan 100
In the process of using Tyracan 100, you may experience the following side effects:Whole body including: Fever, sweating, body aches and pains. Lungs include: New or worsening lung problems such as chest pain, dry cough with fever, wheezing, shortness of breath, shortness of breath, coughing up blood. Neurological include: Sudden headache, confusion, speech or balance, mood swings. Eyes include: Problems with vision, eye pain, red or itchy eyes. Gastrointestinal include: Nausea, vomiting, coffee-colored vomit, stomach pain, extreme thirst, rapid weight gain, severe or persistent diarrhea, or loss of appetite, black stools, blood, like tar. Urination includes: Urinating less than usual or not urinating at all, urine that is dark in color. Skin and subcutaneous tissue including: Pale or yellow skin, peeling and redness, skin that bruises easily, small purple or red spots underneath the skin, dry skin. Mouth includes: There are white patches inside the mouth or on the lips. Blood includes: Abnormal bleeding from the nose, mouth, vagina, or rectum. During the use of Tyracan 100, if you have any unusual symptoms, you should immediately notify your doctor or go to the nearest medical facility for timely treatment.
4. Tyracan 100 interactions with other drugs
Medicines that increase the risk of side effects when used with Tyracan 100 include: azole antifungals (such as ketoconazole, itraconazole, voriconazole), some calcium channel blockers (such as diltiazem, verapamil), fluoroquinolone antibiotics (such as ciprofloxacin), HIV protease inhibitors (such as atazanavir, ritonavir, indinavir, nelfinavir, saquinavir), macrolide antibiotics (such as clarithromycin), nefazodone, telithromycin, or troleandomycin. Drugs that reduce the effectiveness of Tyracan 100 when taken together, such as: Barbiturates (such as phenobarbital), efavirenz, carbamazepine, hydantoins (such as phenytoin), pioglitazone, nevirapine, PPIs (such as omeprazole), rifamycins (such as rifampin, rifabutin) , rifapentine) or the herb St. John's wort When Tyracan 100 is used with these medicines there may be an increased risk of stool problems, which include: Corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs), or certain medicines other. Using Tyracan 100 with anticoagulants (such as warfarin), may increase the risk of bleeding. Taking Tyracan 100 with HMG-CoA reductase inhibitors (statins) (such as simvastatin) increases the risk of muscle problems. There is an increased risk of liver or kidney side effects when Tyracan 100 is taken with drugs that can damage the kidneys such as aminoglycoside antibiotics, amphotericin B, cyclosporine, NSAIDs, tacrolimus, vancomycin; or harmful to the liver such as acetaminophen, some HIV medicines, ketoconazole, isoniazid, methotrexate. To avoid adverse drug interactions, before using Tyracan 100, you should tell your doctor about all the medications you are taking.Reference source: ungthutap.com
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