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Tufsine Cap 200 is a drug in the form of hard capsules, used in the treatment of acute and chronic bronchopulmonary diseases accompanied by mucus secretion. Complying with the indications, the dose of Tufsine Cap 200 will help patients improve the effectiveness of treatment and avoid unwanted side effects.
1. What is Tufsine 200 Cap?
Tufsine 200 Cap belongs to the group of drugs acting on the respiratory tract. The drug is prepared in the form of hard capsules, containing the main ingredient is Acetylcysteine 200mg.
2. What are the uses of Tufsine 200 Cap?
The main use of Tufsine 200 Cap is to remove phlegm and mucus in respiratory diseases.
The main ingredient of Tufsine 200 Cap is Acetylcysteine (N - acetylcysteine), a N - acetyl derivative of L - cysteine, a natural amino - acid, which reduces the viscosity of sputum in the respiratory tract with or without hat by cleaving disulfide bonds in mucoproteins, facilitating expulsion of sputum, orthostatic or mechanical drainage.
In some cases, Acetylcysteine is also used to detoxify the liver in case of paracetamol overdose. Acetylcysteine is responsible for maintaining or restoring hepatic glutathione levels (essential to inactivate the hepatotoxic intermediate metabolite of Paracetamol). Specifically, in overdose of Paracetamol, when using Acetylcysteine, it will convert to cysteine, which helps the liver to stimulate the synthesis of glutathione concentration, inactivate the metabolism of Paracetamol, and reduce symptoms of poisoning. Then, Aacetylcysteine can protect the liver for 12 hours after paracetamol overdose.
3. Indications for use of Tufsine 200 Cap
Mucus in acute and chronic bronchopulmonary diseases accompanied by increased mucus secretion. Treatment of cystic fibrosis of the pancreas. Routine cleaning in tracheostomy. Detoxification of Paracetamol overdose.
4. Contraindications to taking Tufsine 200 Cap
Do not use Tufsine 200 Cap for patients with hypersensitivity to Acetylcysteine, for example asthma or a history of asthma.
5. Dosage of Tufsine 200 Cap
Tufsine 200 Cap for oral use. For adults and children over 7 years old: 200mg/dose, 2-3 times a day. Children 2-7 years old: 200mg/time, 2 times a day. Children under 2 years old: 100mg/time, twice a day. Using Tufsine 200 Cap for patients with Paracetamol overdose: When a Paracetamol overdose is diagnosed, Tufsine 200 Cap must be given to the patient immediately, within less than 36 hours of taking Paracetamol. Treatment with Tufsine 200 cap is most effective in less than 10 hours after the patient overdose Paracetamol. The dose of Tufsine 200 Cap for patients with Paracetamol overdose is 140mg/kg for the first dose. After the first dose, another 17 doses of 70 mg/kg should be continued at least every 4 hours. Plasma Paracetamol test showed low risk of hepatotoxicity, then discontinue use of Tufsine 200 Cap.
6. Notes when using Tufsine 200 Cap
If Acetylcysteine is used in combination with Tetracycline, it must be taken at least 2 hours apart. Acetylcysteine should not be used concurrently with other cough suppressants because there is a risk of serious mucus congestion due to the patient's decreased cough reflex. Acetylcysteine is a reducing agent – should not be combined with oxidizing compounds. Management of missed dose of Tufsine 200 cap: In case the patient misses a dose of Tufsine 200 cap, just take the next dose. Never take a double dose to replace a previously missed dose. Treatment of Tufsine 200 Cap overdose: If an overdose of Tufsine 200 Cap occurs, you should immediately report it to your doctor or if you see any abnormal symptoms, you need to go to the hospital for timely treatment.
7. Side effects when using Tufsine 200 Cap
Tufsine 200 Cap is safe for both pregnant and lactating women. However, side effects of Tufsine 200 Cap also include nausea, headache and tinnitus, stomatitis, and mild urticaria.
Rare cases of serious side effects such as gastrointestinal disturbances, bronchospasm, systemic anaphylactic reactions, fever and chills.
Other undesirable effects: Flushing, syncope, sweating, joint pain, blurred vision, liver dysfunction, acidosis, convulsions, respiratory arrest.
Tufsine 200 Cap is a medicine that thins mucus to circulate through the lungs and ease the passage of mucus (phlegm) through the respiratory tract. The drug is in the form of hard capsules and is easily absorbed orally. Patients should carefully read the instructions for use, consult a doctor / pharmacist before using to ensure safety for health.
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