This is an automatically translated article.
Tranoxel is one of the drugs indicated for use in the treatment of abnormal bleeding cases related to Fibrin factor. The drug contains Tranexamic acid with anti-allergic, anti-inflammatory, anti-plasmin, and hemostatic effects. In addition, the drug is very effective in treating melasma.
1. What is Tranoxel?
Tranoxel is one of the drugs that works well for the treatment of blood problems. The drug contains the main ingredient is Tranexamic acid 250mg/5ml.
Tranexamic acid is an active ingredient that inhibits the fibrinolysis system through inhibiting the activation of plasminogens to prevent the formation of plasmins. Tranexamic acid has two main forms of use: oral tablets and injections. Depending on the purpose of treatment and the condition of the patient to choose the appropriate form of use.
Effects of Tranoxel include:
Anti-plasmin: When entering the body, Tranexamic acid will bind to Lysine binding sites, this is the site with affinity for plasmin and plasminogen Fibrin fibers, thereby preventing the binding of plasmin and plasminogen to fibrin. Hemostasis: Excessive increase in plasmin will cause inhibition of platelet aggregation and breakdown of coagulation agents, and fibrin degradation occurs. Thanks to its ability to eliminate the breakdown of fibrin, Tranexamic acid helps to stop bleeding in cases of normal bleeding. Anti-allergic, anti-inflammatory: Tranexamic acid can inhibit the production of active peptides, inhibit kinin production, increase vascular permeability, reduce allergic reactions and inflammatory lesions. You may not know it, but today, Tranexamic acid is relatively common in topical creams or serums. After many studies on the effect of the active ingredient Tranexamic acid on the skin, scientists concluded that, in addition to the ability to stop bleeding, Tranexamic acid also has a very good effect in the treatment of melasma, improving the condition of the cheeks. dark spots and brighten, even skin tone. Tranexamic acid can be used alone or in combination with other active ingredients to increase the therapeutic effect.
Tranexamic acid is indicated in the treatment of:
Cases at risk of bleeding associated with increased fibrinolysis such as non-regenerative anemia, purpura or leukemia... Indications for hemostasis when there is abnormal bleeding before and during surgery. Abnormal bleeding in the genitals, kidneys, nose, lungs... is suspected to be related to increased fibrinolysis. Treatment of drug poisoning, allergies, urticaria, tonsillitis, laryngitis... In dermatology, Tranexamic acid is indicated in the treatment of melasma, freckles or skin pigmentation problems. Contraindicated to use the drug with:
People with a history of allergy or hypersensitivity to any ingredient of the drug. Because the main ingredient of the drug is Tranexamic acid, the drug should not be used if the patient is on coagulation therapy, has thrombosis or is at risk of thrombosis. Do not use the drug in patients with severe renal impairment because of the risk of drug accumulation.
2. Dosage and how to use Tranoxel
Tranoxel is produced as a solution for injection, packed in 10 ampoules, each containing 5ml of the drug equivalent to 250mg of Tranexamic acid.
The drug is administered in the form of intramuscular injection, intravenous injection or intravenous infusion.
Dosage of Tranoxel:
Intravenous (IV) or intramuscular (IM): 250 - 500mg/day divided 1-2 times. Intravenous infusion during and after surgery: 500 - 2500 mg/time. If used intravenously, use 500-1000 mg/time.
3. Side effects and notes when taking Tranoxel
Some possible side effects when taking Tranoxel:
Digestive disorders causing loss of appetite, fatigue, vomiting, nausea, diarrhea, or heartburn. Hypersensitivity reactions, drug allergies, and anaphylaxis may occur. Skin rash, urticaria. Rare side effects associated with Tranexamic acid: drowsiness, headache or short-term loss of color discrimination. To limit the risk of unwanted effects, when using it, it is necessary to note the following:
Use the drug strictly according to the instructions of the doctor, do not increase or decrease the dose of the drug without consulting the doctor. medical professionals or people with medical expertise. The drug is produced in the form of an infusion solution, absolutely not for oral use or other drug routes. Use caution when using the drug with the elderly, children under 15 years of age, people with thrombotic diseases or diseases related to coagulation destruction. For pregnant and lactating women, if it is necessary to take the drug, it is necessary to consult a specialist before using it. Do not use together with alcohol, tobacco or other stimulants. Although rare, there is a risk of a drowsy headache. For safety, use caution when driving or operating machinery. Store medications according to the manufacturer's instructions. Keep medicine out of reach of children, children can drink or break the tube and step on broken pieces. Not only Tranoxe l but any drug has both advantages and disadvantages when used. Therefore, it is very important not only for patients but also for medical professionals to understand how to use drugs correctly. Do not self-medicate, contact a specialist or the nearest medical facility if you need health advice for guidance on the best and safe treatment methods.
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