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Tizanad 2mg is a prescribed muscle relaxant with the main ingredient being 2mg Tizanidin in the form of Tizanidin HCl. The drug is used in the treatment of certain medical conditions. So what is Tizanad 2mg drug and how to use this medicine?1. What is Tizanad 2mg?
What is Tizanad 2mg? The drug Tizanad 2mg is a muscle relaxant, the drug is made in the form of tablets with the main ingredient in each tablet is 2mg Tizanidin in the form of Tizanidin HCl. Tizanidine is a muscle relaxant that acts on the central nervous system. The main site of action of this active ingredient is in the spinal cord, it stimulates the a2 receptor in the presynaptic region, inhibiting the release of amino acids that stimulate the N-methyl-D-aspartate receptor.
This active ingredient inhibits multi-synaptic nerve transmission in the spinal cord, which is a transmission pathway that increases muscle tone, so Tizanad 2mg has an inhibitory effect and reduces muscle tone. In addition, active ingredient Tizanidine also has moderate central analgesic effect. Tizanidine is effective in acute painful muscle spasms as well as chronic spasticity originating in the brain and spinal cord. Tizanidine reduces resistance to passive movements, reduces convulsions and tremors, and helps to improve active muscle movements.
2. Indications and contraindications Tizanad 2mg
2.1. Indications Tizanad 2mg is indicated in the following cases of painful muscle spasms:
Disorders of balance and function in the spine area such as neck or lumbar syndrome, torticollis or back pain. After surgery: surgery for herniated disc or osteoarthritis in the hip. Nervous spasticity: Multiple sclerosis Chronic spinal disease Chronic spinal degenerative disease Cerebrovascular accident Cerebral palsy. 2.2. Contraindications Tizanad 2mg is contraindicated in the following cases:
People with hypersensitivity to the drug Severe liver failure.
3. Dosage and how to use Tizanad 2mg
Tizanad 2mg drug is used orally, the patient should take the drug with a sufficient amount of water. Dosage should follow the doctor's prescription, reference dose for specific cases as follows:
Soothe painful muscle spasms: Use dose 1-2 tablets/time, 3 times/day. In severe cases, you can take 1-2 more pills before going to bed at night. Treatment of spasticity, the consequences of neurological disorders: Use the starting dose ≤ 3 tablets/day, divided into 2-3 oral doses. The dose can then be increased by 1-2 tablets every fortnight or week. The optimal therapeutic effect of the drug Tizanad 2mg is recorded with a daily dose of usually 6-12 tablets, divided into 3 or 4 oral doses. It should be noted, do not use more than 18 tablets (36 mg)/day. There have been a number of cases of overdose of Tizanad 2mg drug reported, the results showed that the patient recovered completely even in the case of taking 400mg. Symptoms of an overdose of Tizanad 2mg include:
Vomiting Low blood pressure Dizziness Mydriasis Respiratory failure Coma. Currently, there is no specific antidote for Tizanad 2mg in overdose. Treatment for drug overdose is as follows:
Wash the intestines, then use activated charcoal. Increased diuresis Respiratory and cardiovascular support.
3. Side effects of the drug Tizanad 2mg
If Tizanad 2mg is used at the recommended dose in the treatment of painful muscle spasms, side effects are very rare and if they do occur, they are only mild and transient, for example:
Drowsiness Fatigue Dizziness face Dry mouth Slight drop in blood pressure. Rare side effects include:
Vomiting Gastrointestinal disturbances Transaminase elevations. When Tizanad 2mg is used at doses higher than those recommended for the treatment of tremor, these side effects are more frequent and may be severe. However, it is rarely necessary to discontinue treatment with Tizanad 2mg. It can sometimes cause hypotension and bradycardia.
During the use of Tizanad 2mg, if the patient shows any unusual symptoms, they should immediately notify the doctor or go to the nearest medical facility for timely treatment.
4. Interaction of Tizanad 2mg with other drugs
If Tizanad 2mg is used concurrently with antihypertensive drugs or diuretics, it may cause hypotension and bradycardia. Alcohol and sedatives used with Tizanad 2mg may increase the sedative effect of Tizanidine.
5. Be careful when taking Tizanad 2mg
Currently, liver failure has been reported when tizanidine is used at a dose of 12 mg, so it is recommended to monitor the patient's liver function during the first 4 months of using a dose of ≥ 12 mg. Accordingly, when patients have symptoms suggestive of liver function impairment such as nausea, anorexia, fatigue, Tizanad 2mg should be discontinued when SGOT and SGPT indexes are 3 times higher than normal. In patients with renal impairment with creatinine clearance < 25 ml/min, tizanad 2 mg should be used with an initial dose of 2 mg/day. Increase dose gradually, depending on tolerability and effectiveness. If symptoms improve, Tizanad 2mg once a day should be used before increasing it to several times a day. Patients who feel drowsy when starting Tizanad 2mg should not perform tasks requiring alertness such as driving or operating machinery. In studies, Tizanidine was not teratogenic in animals. However, the safety of Tizanad 2mg when used in pregnant women has not been established, so you should not take this medicine if you are pregnant. The current knowledge of scientists about the excretion of Tizanad 2mg in breast milk is limited, so it is not recommended for use in lactating women. Tizanad 2mg is a prescription muscle relaxant with the main ingredient being 2mg Tizanidin as Tizanidin HCl. The drug is used in the treatment of certain medical conditions. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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