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Drug Modium belongs to the group of gastrointestinal drugs. So what is the use of Modium, and in what cases is it indicated?
1. What is Modium?
Modium medicine has the main ingredient containing the active ingredient Loperamide, which is made in the form of a syrup, packed in a box of 1 bottle with a capacity of 100ml.
2. Effects of the drug Modium
2.1. The effect of the drug Modium Active ingredient Loperamide in Modium is a medicine used to treat acute diarrhea of unknown etiology and some chronic diarrhea conditions. Loperamide is a synthetic opiate that, when used in normal doses, has little or no effect on the central nervous system. Active ingredient Loperamide helps reduce secretions in the digestive tract, reduces intestinal motility, increases the tone of the anal sphincter. In addition, the drug Modium also works to increase the transport of fluids and electrolytes, prolong the transit time through the intestines, and reduce the amount of stool. The decrease in prostaglandin and acetylcholine release is probably related to the above effects of the drug.
2.2. Indications for the drug Modium Modium is indicated for use in the following cases:
Modium is indicated for the relief of symptoms of acute nonspecific diarrhea in adults and children > 12 years of age, chronic diarrhea of primary origin. caused by intestinal inflammation. In patients undergoing ileostomy, use of Modium helps to reduce stool volume, decrease frequency of bowel movements, and increase stool consistency. For episodes of acute diarrhea associated with irritable bowel syndrome in adults > 18 years of age with a preliminary diagnosis by a physician, use Modium for symptomatic treatment. 2.3. Contraindications to the drug Modium The drug Modium is contraindicated in the following cases:
Modium is not used in young people and children under 12 years of age. The drug will be accumulated and not eliminated through the liver in subjects with impaired liver function, so do not use Modium in this subject because it will lead to an overdose. Active ingredient Loperamide is only used to treat symptoms, so it should not be used in dysentery syndrome. Do not use Modium in patients with invasive bacterial enteritis, acute ulcerative colitis, acute dysentery characterized by high fever and blood in the stools, pseudomembranous colitis or acute antibiotic-associated ulcerative colitis. caused by broad spectrum. Modium is contraindicated for use in patients who need to avoid inhibition of intestinal motility. Subjects are hypersensitive to any of the ingredients of Modium. The drug must be discontinued immediately when symptoms such as abdominal distension, constipation, semi-obstruction progress.
3. Usage and dosage of the drug Modium
3.1. How to use Modium is taken orally, shake the bottle well to mix the active ingredients and excipients in the solution.
3.2. Dosage For acute diarrhea:
Adults: The starting dose is 4mg, the patient can use each 2mg after each loose stool, the maximum dose in 1 day is 16mg. Children: from 6 to 8 years old: use 2 times a day, 2mg each time, children from 8 to 12 years old, use 3 times a day, 1 time 2mg, from day 2 use 1mg/10kg of body weight after each bowel loose stools, the maximum total dose of 1 day should not exceed the dose of the first day. For chronic diarrhea:
Adults: can be taken once a day or divided into several times, the dose is from 4 to 8 mg/day. Children: no research data available.
4. Undesirable effects of using the drug Modium
Common side effects when using Modium such as: abdominal distension, constipation, epigastric pain, dry mouth, fatigue, dizziness, insomnia. These symptoms will often be difficult to distinguish from those associated with the diarrheal syndrome. -The rarer side effects such as intestinal obstruction mostly occur because the patient does not follow the instructions for use. Hypersensitivity reactions such as: urticaria, skin rash, anaphylaxis, toxic epidermal necrolysis.
5. Pay attention to the use of the drug Modium
Do not use for lactating women and children under 12 years old.
Dehydration and electrolyte loss can occur in patients with diarrhea, so in these cases, appropriate rehydration therapy is most important.
When the patient has been treated with Modium, but clinically the symptoms of acute diarrhea do not improve within 48 hours, the use of Modium should be stopped to review and find the cause of the diarrhea.
Modium can cause CNS toxicity, because of the phase 1 metabolism, patients with liver dysfunction need to be closely monitored for these signs of toxicity.
The use of Modium should be discontinued when treating acute diarrhea in AIDS patients when early symptoms such as abdominal distension appear.
Hopefully with the sharing of Modium medicine, it will help you know how to use and use the drug to achieve effectiveness in treatment and cure.
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