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Donamkit is used to relieve symptoms of discomfort, loss of appetite, abdominal pain, indigestion caused by peptic ulcer disease, gastroesophageal reflux disease. Learn some information about uses, doses and precautions when using Donamkit to help patients use the drug safely and effectively.
1. Ingredients of the drug Donamkit
Donamkit medicine is made in the form of tablets, containing the following ingredients:
Pantoprazol 40mg. Clarithromycin 500mg; Tinidazole 500mg.
2. What is the effect of the drug Donamkit?
Donamkit is used in the treatment of the following diseases:
Peptic ulcer; Gastroesophageal reflux ; Combination with 2 appropriate antibiotics to eradicate Helicobacter pylori in patients with peptic ulcer, heal ulcer and prevent recurrence.
3. Contraindications to taking the drug Donamkit
Donamkit drug should not be used in the following cases:
Patients with hypersensitivity to antibiotics of the Macrolide group or components and excipients of Donamkit. Persons being treated with Terfenadine with a history of heart disease or electrolyte disturbances. Patients who are taking derivatives such as Ergotamine, Cisaprid and Pimoside.. Contraindication is understood as an absolute contraindication, which means that for any reason, the contraindication is flexible enough to use Donamkit. .
4. Dosage, how to use the drug Donamkit
Dosage of Donamkit:
Recommended dose in patients with peptic ulcer disease, Helicobacter pylori infection, eradication of bacteria by combination therapy. Depending on the type of drug resistance, the following combination scheme can be used to kill Helicobacter pylori bacteria: Treatment regimen 1: Take 2 times daily x (1 tablet of Pantoprazole + 1000mg of Amoxicillin + 500mg of Clarithromycin) for 7 days. Treatment regimen 2: Take 2 times a day x (1 tablet of Pantoprazole + 500mg of Metronidazol + 500mg of Clarithromycin) for 7 days. Treatment regimen 3: Take 2 times a day x (1 tablet of Pantoprazole + 1000mg of Amoxicillin + 500mg of Metronidazol) for 7 days. Gastroesophageal reflux disease (GERD): Take 1 tablet of Donamkit 40mg/day. For patients with severe liver failure, the dose of Donamkit should be reduced to 1 tablet x 2 days/time. If liver enzymes are elevated, pantoprazole should be discontinued. Do not exceed a dose of 40 mg Pantoprazole per day in the elderly or in renal impairment. The exception is combination therapy for the eradication of Helicobacter pylori, in which the elderly must also receive the usual dose of Pantoprazole (2 x 40 mg/day) for 1 week of treatment. How to take Donamkit:
Take Donamkit whole tablets with water 1 hour before breakfast. In combination therapy for the eradication of Helicobacter pylori, the 2nd Donamkit tablet should be taken before dinner. If you forget to take Donamkit on time, do not take the make up dose later in the day, continue taking the usual dose the next day in the course. Combination therapy requires only 7 days of treatment to eradicate Helicobacter pylori and heal ulcers. Note: The above dose of Donamkit is for reference only. The specific dose of Donamkit will depend on the condition and the progression of the disease. To have the right dose of Donamkit, patients need to consult their doctor/pharmacist.
5. Be careful when using the drug Donamkit
Donamkit should be used with caution in the following patients:
The elderly, pregnant and lactating women; Children under 15 years old; People with liver failure, kidney failure; People with myasthenia gravis, hepatic coma, stomach ulcers; Caution should be exercised when using Donamkit when driving a vehicle and operating machinery.
6. Side effects of the drug Donamkit
During the use of Donamkit, patients may still experience side effects such as:
Headache, mild diarrhea; Nausea, upper abdominal pain, bloating; Skin rash, itching ; Dizzy; Edema, fever; Thrombophlebitis. If there are any abnormal symptoms suspected of using Donamkit, the patient should notify the treating doctor/pharmacist for timely treatment.
7. Interactions with other drugs
Active ingredient Clarithromycin in the drug Donamkit interacts with alkaloid derivatives causing vasoconstriction of ergot and increases the toxicity of these substances, so it should not be used concurrently. Clarithromycin can also increase the concentration of drugs such as Warfarin, Triazolam, Lovastatin, Disopyramid, Phenytoin and Cylosporin... Therefore, caution should be exercised when combining them. Clarithromycin increases the concentration of Theophyllin in the blood. Clarithromycin may increase the potency of Carbamazepine by decreasing the rate of excretion. Clarithromycin should not be given to patients taking terfenadine or any related non-sedating antihistamines. Decreased steady-state zidovudine concentrations in HIV-infected subjects when co-administered with clarithromycin. To avoid this interaction, it is recommended that the dose of clarithromycin and zidovudine be crossed by approximately 1-2 hours. In order to avoid unwanted interactions when using Donamkit, patients should inform their doctor/pharmacist of all medicines, dietary supplements and herbs... they are taking.
The above is important information about the drug Donamkit, patients should carefully read the instructions for use and use according to the dose prescribed by the doctor to achieve the best effect. Store Donamkit at a temperature of 15-30 degrees Celsius, out of reach of children and pets.
